Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76149	Olaparib	GSE92742	MCF10A	Human	24h	2uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	125	KLF9; HDAC9; FOXA1; HDAC6; CREB5; EWSR1; DDX5; RYBP; SMAD2; BRIP1; NCOR2; SREBF1; TRIP6; ATF2; TFAM; POLR3F; CBFB; FOXN3; RBBP5; ERG; RNF138; FOXN2; MDM4; PMF1; SIX6; MAFF; ZMYM2; MEN1; TDRD3; ZNF529; NANOG; TGS1; HLX; SIRT2; CBFA2T3; HES1; YEATS4; RFX7; TFEC; ZHX2; ZNF135; ZNF532; NKX3-1; ETV4; SALL2; SSRP1; NR4A1; CCDC59; HMGB1; CRY1; PRKDC; CTBP2; ETS2; MEOX2; HOXB2; RARA; ATF1; CCNT1; CRYM; ZNF195; TSC22D1; MED24; NLK; MEOX1; MEF2D; PSMD9; RBPMS; TRRAP; HMBOX1; RB1; ZBTB20; FLI1; ZMIZ1; MED17; SAP18; HOXB6; ECD; HEY1; CLOCK; CUX2; MED4; MAGED1; HLF; PRPF6; PBX3; YWHAB; FOSL1; INSR; TERF1; SUZ12; CRK; TCF21; KAT6A; HOXB13; HOXD1; CHD1; TSC22D2; TLE4; TCF7; HOXA5; PCGF2; PBX1; TRIM29; ZNF274; C1D; SPDEF; MYRF; TSC22D3; ST18; ZBTB18; ACTL6A; PPRC1; JUND; ZNF302; EGR3; ATF3; AEBP1; SNAI2; SOX11; ZIC1; ZNF91; RUNX3; STAT6; BHLHE41; HOXB7
Down-regulation	164	PCGF3; NFKBIA; TRIM32; RFC1; CALCOCO1; FOXF2; NEUROD1; ZXDC; OSR2; PRRX2; NFKB2; MBD3; SOHLH2; TRIM25; ATF4; MLLT10; RNF4; ID4; MXI1; JAK2; VGLL1; RBPJ; SIAH2; RNF14; TRAK1; FOXM1; TFDP2; SATB2; MYOD1; TBL1X; ZSCAN32; ZNF16; HLTF; ZBTB1; ZNF7; LPIN2; DAXX; RBBP7; SP140; TAF12; NFRKB; ARNTL2; WHSC1; ZNF250; DLX5; GATA6; UBP1; PAX6; RXRA; E2F2; PHIP; TBX21; ELF5; IRF3; KDM2A; URI1; HSF1; KLF10; NFATC3; ZNF629; ELF2; SRCAP; PPARD; TCF3; HOXC11; DACH1; OVOL2; RERE; ZNF44; CSDE1; PKNOX1; TCERG1; SPIB; ZNF217; KAT2B; MZF1; FLNA; NR1D2; ELF4; SP100; ZNF419; CARHSP1; CIZ1; CNBP; RBFOX2; EDF1; POU4F1; ZFPM2; SERTAD2; HDAC1; ZNF816; RARG; ZNF426; CREB3L1; EYA2; SALL1; SATB1; BHLHE40; BRD3; GRHL2; ELF3; WWTR1; DDX17; SREBF2; HMGA1; BRD7; MSX1; ZNF665; STAT3; RBBP4; TLE2; CARM1; ZNF148; MECOM; PSIP1; XBP1; DBP; MYCL; ZFHX3; ZNF580; KDM5A; ARID3A; CHD3; IRF5; ZNF264; AFF1; FOXF1; CITED2; ZEB2; YBX1; E2F5; KLF11; TLE1; WNT4; HOXC4; MEIS1; ESR1; CREB1; MNDA; GATA2; REL; BASP1; CBX6; TGIF1; ATF5; HIRA; MEIS2; IKZF1; ABL1; PAWR; SOX10; VDR; TGFB1I1; NR2F2; ZBTB38; BIRC2; MAF; TCFL5; ZNF586; NUP62; GATA3; PEG3; TRPS1; TXNIP