Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76148	Olaparib	GSE92742	MCF10A	Human	24h	10uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	125	KDM5A; ZNF226; TOPORS; CREB3; EHF; TRIP6; MAFF; HSF2; ZNF143; BRIP1; ITGB3BP; YEATS4; MNAT1; VEZF1; SKI; SMAD5; SMARCA2; CSDE1; LITAF; BLZF1; CRY1; HMGA1; ELK3; TTF2; SKIL; RRN3; RELA; ZFX; STAT4; CBFB; IKZF5; BAZ1A; RBL2; MED7; ETV5; NFYA; MED4; EGR4; TFAM; PHF2; TEAD1; RSF1; ZNF432; ZNF32; C1D; RBBP5; ZHX2; OLIG2; SFPQ; THAP1; SOX9; FOXA1; HOXA5; RFX7; PTTG1; MED6; ARID4B; BMI1; ATF1; L3MBTL1; ELK4; NCOR1; MED1; SUB1; HMGB1; FOSL1; HIVEP2; WWC1; CCDC59; MED17; ZBTB38; RB1; CUX2; ZMYND11; ZNF274; KAT5; TCF7L2; TBP; NFAT5; ASCL1; STAT6; PBX1; ABL1; HIPK3; AFF1; PMF1; RFX5; HTATIP2; BBX; TAF9B; ID3; BIRC2; CRYM; SAP18; TBL1XR1; EGR3; ASH2L; LOXL2; UBE2I; ZBTB18; RFXANK; SATB2; MYCBP; PRKDC; UBE2B; ACTL6A; CRK; YAP1; TSC22D3; MYBL1; PCGF2; FOXD1; EDF1; CREG1; TSC22D1; PSIP1; TGFB1; HLX; PFDN5; TOX3; ETS2; JUND; TCERG1; CEBPB; BASP1
Down-regulation	135	OSR2; LMCD1; ZNF711; TFDP2; PAX6; CNBP; TULP4; ZFP36L2; SALL1; NFE2L2; ZNF611; HMGN3; ZNF688; ZXDC; MNT; LEF1; TCF4; GATA6; HDAC4; FOXF2; BHLHE40; IRF6; EN2; TCF7L1; ZIC1; NFKB2; PRDM4; DACH1; HEY1; EYA1; ZNF816; TBL1X; HOXC6; SSBP3; BACH1; ZNF665; MAF; ESR1; KLF4; HIC2; ZNF444; ERG; ZMYND8; TRAK1; ZNF44; NR2F6; SMAD1; PRDM2; HOXB7; MNDA; DAXX; ZNF211; CUX1; NCOA1; NCOR2; VPS72; KLF7; RARG; MAGED1; RREB1; ZNF264; LIN28A; KLF11; WNT4; HIRA; IRF5; OVOL2; ZNF423; SERTAD2; TBX3; MEF2A; PSMD9; CBX4; DLX5; HOXD1; EP300; KLF3; HOXD3; NR2C1; ZFHX3; ZSCAN18; CD3D; CEBPG; ZNF160; HOXB6; GRHL2; DBP; NKX2-1; KDM5D; E2F5; ZNF586; HOXC4; CREB1; CARHSP1; JUP; CREBL2; SIAH2; MLXIP; TRPS1; NR4A2; MYB; HMGB2; ARID5B; SPEN; TCF7; SMARCA1; XBP1; DMTF1; ZNF544; STAT5A; THAP11; TOX; ERBB4; PAWR; SOX11; HMGA2; ID4; AEBP1; ZNF580; TGFB1I1; GATA3; CBX6; ATF5; ZNF512B; ZNF331; ZEB1; IRF4; EGR2; GATA2; IKZF1; KAT6B; TCFL5; TLE1; MEIS2; POU2AF1