Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76147	Azd-8330	GSE92742	MCF10A	Human	24h	0.08uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	151	HDAC9; TAF10; SSBP2; HDAC6; NCOR2; LEF1; TSC22D3; PRKDC; INSM1; HOXA6; PCBD1; ADRB2; SOX17; ZNF224; ZFP36L2; DMRT1; MDM4; RFX7; HIVEP2; JUNB; PHF8; HEY1; TADA3; ZNF669; FOXN2; TTF2; MED1; MED13; SMARCA2; CERS4; AATF; BAZ2A; ANKRD1; ZMYM2; SIRT2; CREB3; ERF; MBD2; TWIST1; DDIT3; FOXO4; POU3F2; RELA; SOX15; COPS5; GATAD2A; FOSB; ZNF155; TDRD3; MAFF; RFXANK; KLF9; NCOA3; MNT; MAZ; ZNF302; TRIM29; BRD2; MED24; NFE2L1; RFX5; ZNF532; CHD4; AES; SNAI2; DACH1; ELF1; FOXO3; NCOA2; LDB1; CITED1; SREBF1; NFKBIA; HOXA5; RNF6; TCF12; MTDH; KLF5; ZNF165; TAF7; RB1; ECD; TLE1; WNT4; NHLH2; PBXIP1; XRCC6; ATF1; HMBOX1; SAP18; BRD4; HTATIP2; USF2; ZNF394; HOXB13; BTG1; USP22; HDAC1; BAZ2B; BCL6; TRIM22; CUX2; RUNX1; KAT2A; ID3; ZIC1; SCAND1; UBE2I; JUND; VGLL4; PMF1; TRIM16; TCEA1; SND1; ATF3; MLX; ZNF83; PBX3; KAT8; FOSL2; ZNF652; ZHX2; FOXA2; ID1; ZNF274; PNRC1; AIP; CRK; NEDD8; STAT6; KLF7; CUX1; ARID5B; ZNF131; TAF1D; HES1; ZNF91; PDLIM1; BIRC2; ASH2L; MEIS1; EMX2; PFDN5; TCEB2; TSC22D1; AEBP1; ACTL6A; MTF2; IKBKAP; TOX3; CEBPB
Down-regulation	193	CCNA2; FOXM1; HMGB2; PCGF3; RFC1; ZFP36L1; CENPF; SMARCA1; NFKB2; ZNF282; DNMT3B; SNAPC4; TAF1A; RORA; RNF4; SP3; WWTR1; TBL1X; GCFC2; PHIP; CHAF1B; GTF2A2; RBPJ; CBX3; TRIM32; HLF; ARNTL2; ARID4A; WHSC1; BACH1; FOXC1; E2F1; ZBTB39; SUMO1; E2F2; HOXC10; FHL2; ZNF180; PAX6; HMGA2; RBL1; BATF3; DAXX; SKI; ENO1; ZNF671; MED7; E2F8; BCLAF1; DR1; SALL1; ID4; NOC2L; ZBTB20; GTF2I; MNDA; ING1; MYBL2; HMGXB4; ZNF329; HLTF; NFE2L2; RERE; ZZZ3; KDM5D; DNAJC2; RREB1; ZNF211; TAF9B; EZH2; FOXF1; ZBED1; IRF4; HOXC11; TEAD3; ZNF264; SIAH2; LIMD1; BANP; XBP1; VGLL1; SERTAD2; CARHSP1; TGIF1; PLAGL1; FOXF2; CDYL; SAP130; ZNF253; CCNE1; CARM1; CTBP1; TTF1; ZNF200; ZNF148; ZNF184; PKNOX1; NFATC3; CREB3L2; BRD3; TULP4; BHLHE40; TAF5; ERCC3; CENPB; CITED2; GRHL2; NKX2-2; MAF; ITGB3BP; AR; SUV39H1; ZNF586; NR1H3; ZNF43; SMARCA4; ZNF134; ELK3; MYCL; URI1; HSBP1; SOX11; CBX6; NR0B1; HOXB2; ZNF273; ZNF512B; BLM; TCF4; ING2; MGA; ZNF217; NFIB; PSMD9; NPM1; HHEX; NELFB; RBPMS; YWHAB; IKZF1; PITX1; HDGF; TCF21; NKX2-1; KAT6A; SATB1; RUNX3; AGO2; AHR; CREB1; PTTG1; ZNF304; TRPS1; EGR3; KLF11; ETV5; MECP2; MYB; NFKB1; MYCBP; NR2F2; HMGB3; ERBB4; FOSL1; NR2F1; TGFB1I1; BHLHE41; GATA2; ESR1; EGR2; SOX10; SPEN; ZSCAN18; NR4A2; SATB2; ATF5; OSR2; TXNIP; ELF5; IRX5; POU2AF1; SMAD1; MEIS2; ZBTB38; IRF8; BRCA1; HOXB7; GATA3; TCFL5; PARP1; PEG3; KAT6B; WT1