Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76146	Azd-8330	GSE92742	MCF10A	Human	24h	0.4uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	139	HDAC9; TSC22D3; ADRB2; TAF10; RSF1; SIRT7; NCOR2; CRYM; ZNF430; INSM1; ATF2; BTG1; FOXO4; MED13; HDAC5; PRKDC; ZNF140; SNAI2; FOXI1; ZKSCAN1; CREG1; MED1; TRIP11; CSDE1; CHD8; ZNF611; TRIM16; TEAD1; MAZ; SIRT2; ZMYM2; LITAF; ZNF195; ZFP36L2; PBXIP1; TAF5L; ZNF224; BLZF1; PPARGC1A; DDIT3; TRIM29; BAZ1A; CDK8; SREBF1; FOXK2; RB1; MITF; TLE1; NCOA2; SP110; TRIM22; TCF25; BRD2; GTF2F1; ZNF669; SIX2; BCL11A; CUX2; CTBP2; RBBP5; MKL2; ZNF665; FOSB; CERS6; ZNF160; ZFX; PFDN5; NFKBIA; ASCL1; TTF2; FOXO1; ZNF93; PBX1; ISL1; ZNF468; HTATIP2; RXRA; HBP1; SREBF2; BACH2; NFE2L1; FOXO3; KLF5; ZNF426; ZNF652; IFI16; SFPQ; ARID4B; ZNF274; ZNF721; EYA2; STAT6; RNF6; STAT1; TSC22D2; TWIST1; MMS19; PDLIM1; CRK; MED24; RNF10; ZNF394; REL; RLF; TCF12; SPDEF; VGLL4; BPTF; BCL10; IRF9; IRF7; KDM5B; ZNF302; ETS2; ZNF85; RUNX1; YEATS2; JUNB; BBX; MDM2; ZNF146; ATF1; PNRC1; ATF3; ZNF91; EHF; TCEB2; ELF1; ID1; ATF5; ZBTB18; NRIP1; CCNH; TCERG1; SMAD3; TSC22D1; JUP; IRF8; CEBPB
Down-regulation	165	CCNA2; FOXM1; NR2F6; HMGB2; WWTR1; TFAP2A; PAX6; CHAF1B; ZNF282; ZNF711; POLR2A; CBX3; TEAD4; TULP4; GTF2I; SOHLH2; FOXF2; SAP30; PCGF3; CAMTA1; RNF4; SMARCD1; BCLAF1; HOXC10; SERTAD2; ZBTB20; RORA; NFIB; WHSC1; BACH1; ENO1; TBL1X; E2F2; ZFPM2; BLM; MYBL2; HOXA1; FOXJ2; BHLHE40; CENPF; HMGA2; KAT2B; CD3D; NFKB2; NR1D2; KDM5D; MEOX2; HOXB7; CNBP; CREM; ZNF329; CARM1; DLX2; NKX2-2; ZNF133; ETV4; FOXL2; VGLL1; DNAJC2; ARNTL2; FHL2; CTCF; DAXX; ZNF248; ARL2BP; HHEX; MED21; CDYL; WT1; ZXDC; CTBP1; ING1; HOXD11; HOXB2; CCNE1; RBM14; NFRKB; FOXC1; ID4; EZH2; HNRNPD; HOXC4; ZNF175; SMARCA1; SIM2; MED12; NCOA6; TLE2; SUV39H1; SMAD6; MNDA; ELK3; ZNF180; HLTF; TAF9B; SPEN; KLF3; BRD7; HLF; FOSL1; IRX5; XBP1; BHLHE41; PTTG1; NR2F1; HOXD3; NFATC3; POU4F1; YWHAB; SOX10; KMT5A; TGFB1I1; SIAH2; NFKB1; TCF21; IKZF1; HOXA5; HES1; SATB1; BRD3; CENPB; URI1; TLE4; EGR2; FOXF1; EN1; HOXC6; TGIF1; TCF4; CREB3L2; CBFB; CBX6; ERBB4; MYBL1; ZNF443; DMTF1; POU2AF1; IRF4; ELF5; ZNF586; PSIP1; PAXBP1; ING2; TRIM28; TOX; RBPMS; TBX2; BRCA1; AHR; IL16; PURA; TCFL5; RUNX3; ZNF131; SUB1; NR4A2; SALL1; GATA3; NR2F2; AEBP1; PARP1; HIC2; GATA2; PEG3; CITED2