Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76144	Azd-8330	GSE92742	MCF10A	Human	24h	10uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	161	INSM1; HDAC6; ADRB2; TSC22D3; TAF10; TRIM16; MED1; TSC22D4; TTF2; CSDE1; BARX2; ZFHX2; LITAF; ZNF205; TRIM29; ZNF652; TSC22D2; SOX15; TRIP6; FOSB; NR4A3; HOXA6; PPARGC1A; JUNB; SETD3; CEBPE; RYBP; ZNF165; SF1; PCGF2; FOXO4; KLF9; MED24; SMARCD2; CREG1; PRKDC; ZMYM2; SMARCA2; HIVEP2; LEF1; ZNF224; RNF141; RSF1; SIRT2; FOXN3; HTATIP2; ZNF768; FOXO3; MLXIPL; AATF; BCL11A; SIM2; RELA; SMARCD3; NCOR2; SOX9; MED13; UBE2L3; ARID4B; TP63; CREB3; NR0B2; ZNF669; NCOA3; HOXA5; ZHX2; RFX5; MEF2D; ID3; TAF11; HDAC1; PBXIP1; DDIT3; THRA; CHD9; UBE3A; TAF7; SNAI2; ZNF430; CITED1; CTBP1; KLF4; MAFF; NFKBIA; TLE1; SMARCC2; POU5F1B; RUNX1; EP400; SAFB2; DACH1; MLX; HSBP1; ETS2; ZFP36L2; ATF3; STAT6; MAZ; ZNF140; HBP1; TRAK1; TWIST1; ATF1; USF2; BAZ2A; IRX4; ZNF394; VGLL4; USP22; HIPK1; LOXL2; ARID5B; MMS19; IRF6; NR0B1; ZKSCAN1; MAF; CRK; TFCP2; DLX2; KLF5; RBBP4; BAZ1A; KLF2; KAT2A; ZNF107; TBP; RFXANK; WNT4; KAT8; PNRC1; CTBP2; TCEB2; PBX3; EHF; BIRC2; ZNF532; MED23; SHOX2; UBE2B; SREBF1; EDF1; NEDD8; CBFB; JUND; ASH2L; SAP18; ZEB2; EMX2; BMI1; ZIC1; ACTL6A; TP53; ATF5; PPRC1; NR4A2; NFATC3; ZBTB18; TOX3; CEBPB; HOXC6
Down-regulation	176	CCNA2; FOXM1; EYA1; SP3; CENPF; NR2F6; TRIM32; SOHLH2; GTF2A2; TEAD4; HMGB2; TBL1X; MEOX2; RFC1; SAP30; NFKB2; HOXB2; WT1; CBX3; SUMO1; KAT2B; HMGXB4; TAF1A; PCGF3; WWTR1; RXRG; SNAPC4; CHAF1B; MED21; USP21; ZNF180; BCLAF1; E2F2; NKX3-2; ZNF711; DAXX; BACH1; ARNTL2; TGFB1I1; SSBP2; HOXD11; NFIB; DNAJC2; ZNF654; RORA; PHF20; DR1; HDAC4; SOX11; HOXD10; ID4; ELF2; ZFP30; TAF9B; SIAH2; SP100; GCFC2; ZNF148; URI1; ZNF239; ZNF329; SAP130; GTF3A; ZNF45; CBX5; ELK4; ELK3; ZXDC; BHLHE40; NFIC; TCEA1; TOPORS; ASXL1; SPEN; SUPT6H; MYT1L; CDYL; ZNF134; SALL1; HOXD3; SP140L; HLF; ZNF3; HOXB7; VGLL1; ZNF8; SUV39H1; TULP4; SCAND1; NCOA6; RREB1; BRD4; NKX2-2; CARM1; PLAGL2; POU2AF1; TOX; PDLIM1; MED12; MAFG; ZFPM2; ZNF211; HDGF; BANP; NR2F2; HOXD1; ZNF22; IRF4; HIRA; TCF7L1; EN1; ZEB1; ZMYND8; WWP1; KLF10; AGO2; POU2F1; AR; ZNF324; OVOL2; SIN3B; PLAGL1; PHOX2B; MLXIP; C1D; CHD1; CBX6; KDM5D; SMARCA1; SMAD1; ESR1; ZNF586; FOXF2; MNDA; ELF5; HMGA2; ZNF266; TCF21; SOX2; IKZF1; ZNF423; TRIM28; ZNF415; ING2; RBBP7; ZNF580; KLF13; ERBB4; ENY2; CBX4; ZNF443; ZNF562; PAWR; PEG3; GRHL2; TRPS1; KDM5A; IL16; E2F6; PSIP1; HMGB3; PRRX1; MEIS2; ZNF264; TGIF1; HOXB6; SATB1; HIC2; GATA6; BHLHE41; HHEX; GATA3; ZNF512B; AEBP1; FOXG1; NUP62