Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76128	Vx-745	GSE92742	MCF10A	Human	24h	0.08uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	99	TTF2; ATF2; NR0B2; BRIP1; ETV4; ZNF195; TFAM; RNF111; TP63; TMF1; YEATS4; MLXIPL; MAML1; RFX7; EWSR1; ILF2; CHD9; SAP30; FOXA2; FLI1; ZBED4; E2F8; PRKDC; VEZF1; ATF1; KLF7; ZKSCAN1; TRIM29; ETV1; ZNF12; ZNF143; HOXA5; ACTL6A; MED1; PMF1; SREBF1; RYBP; MMS19; CUX1; VPS72; USP22; RNF6; SP2; SSRP1; KAT8; HOXA7; MED14; RBBP5; ZNF232; ZFX; SOX15; MDFI; MLXIP; MED27; STAT1; FOXO1; MITF; VGLL4; JUP; MED23; IFI16; PSMD9; PROX1; CBFB; MED13; DPF2; RAD21; ARID4B; MDM2; TSC22D2; PAXBP1; ARNTL2; SFPQ; CRK; RB1; TBP; SNAI2; LITAF; PBX3; TSC22D3; LEF1; ZNF593; SUZ12; FOSL1; ID3; PPRC1; TP53; TAF1D; VDR; TRIM22; TCERG1; ZNF281; SCAND1; TLE1; IKBKAP; ZBTB18; ATF3; MEIS2; CEBPB
Down-regulation	137	HOXC10; NFE2L2; ID4; ZNF329; EYA1; CREM; ZNF331; ESR1; NFKB2; TBL1X; PHF1; TEAD3; LIN28A; SP3; ZNF571; PRRX2; SSBP3; ZNF415; FOXF2; SALL1; SIAH2; ZSCAN18; PHIP; OSR2; HEY2; XBP1; E2F2; CREB3L1; ZNF536; HOXC11; HDAC4; NR4A2; ZNF211; ZNF606; CDYL; MXI1; RORA; KDM5D; URI1; FOXE1; ZNF180; FOSL2; TFDP2; TGIF1; CBX7; TCF7L1; DDX17; ZNF665; IRX5; RARG; FOXF1; ELF3; ZNF274; ZNF419; MAF; PBXIP1; HOXC6; IRF7; ING2; SMARCA1; ZNF580; ZNF148; NKX2-1; BCL3; KLF10; TBX3; BHLHE40; HOXB2; ZSCAN31; NCOA2; ZNF423; SMARCA4; HLF; HMGN3; NR3C2; CARM1; BATF; BHLHE41; SPEN; ZNF134; IRF3; CALR; ZNF586; ZIC1; STAT4; ERBB4; SATB1; ATF4; RBBP7; NR1H2; DNAJC1; CENPB; TRPS1; PSIP1; NR0B1; BASP1; CD3D; ZNF512B; TCEA1; ZFPM2; ZNF266; KLF4; HEY1; BBX; WT1; KAT6B; GRHL2; ZNF217; NCOA1; REL; IKZF1; DLX2; TCF4; HOXC4; TOX; DAXX; TXNIP; NR2F1; TFAP2C; ATF5; NR2F2; ZNF264; MEIS1; TLE4; MAFB; GATA6; ZBTB38; JUND; TGFB1; GATA3; TGFB1I1; HIC2; GATA2; HHEX; FOXG1; POU2AF1; IRF4