Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76126	Vx-745	GSE92742	MCF10A	Human	24h	2uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	196	PHF8; TAF10; HDAC6; SAP30; SMARCA2; CREB3; TSC22D2; DMRT1; TRAF6; MNAT1; TFAM; EED; TTF2; CCDC59; BRIP1; MED1; HSF2; SAFB2; MLXIPL; BAZ1A; ERG; PCBD1; ZNF189; PHF2; ETV1; AATF; RBM14; YAF2; ID3; HCFC2; LEF1; POU3F2; TERF2; ATF1; WDHD1; HES1; BATF3; NFKBIB; KAT8; MED27; MLX; UBE3A; PIAS2; TADA3; PDLIM1; ERBB2; INSM1; SNW1; SMARCA5; PTTG1; XRCC6; POLR2A; TBP; USP22; TAF1A; REXO4; PRKDC; ZBED1; VEZF1; SUPT3H; NR1I2; NEDD8; EGR1; ZNF143; LHX2; DDX5; MSC; NR2E1; PATZ1; AFF4; ADRB2; RELA; PTRF; CREB5; TAF9; TMF1; ZBED4; FOSB; YEATS4; SOX9; RRN3; RFX7; SMAD5; ZNF410; PCGF2; HOXA5; CTR9; GABPA; MTDH; SF1; MAFF; CBFB; RNF6; SMAD2; BAZ1B; BCL10; BAZ2A; CHD9; MKL1; ING3; MTA1; HLX; ZNF384; ZNF140; HMGA1; ASH2L; ZNF281; TRRAP; RYBP; ARID4B; GATAD2A; BRF2; NELFB; EDF1; TFEB; TSC22D3; EP400; BRCA1; CRY1; NCOR2; CRK; PSMD9; DPF2; EZH2; SIX2; UBE2L3; SATB2; NCOA4; BAZ2B; ELF1; EMX2; PMF1; MYCBP; SRF; RUNX3; RFX5; LITAF; KMT2B; SP2; TFEC; C1D; HTATIP2; BACH2; FOSL1; SREBF1; KDM5D; FLNA; HDAC1; GABPB1; IKBKAP; MSX1; REPIN1; TRIM16; PBX3; TCERG1; TRIP6; COPS5; ENY2; ZEB2; SOX4; ATF3; FOS; RNF138; ZNF267; JUND; HOXB7; BRD8; ETS2; SMAD1; STAT6; CTNNB1; CCNC; ZNF302; MYRF; MAX; PSIP1; TRIM29; LOXL2; BHLHE41; RHOA; SUZ12; NRIP1; ZBTB18; SOX11; MTF2; MYB; MEIS1; ATF5; PEG3; SMAD7; NKX3-1; VDR; EGR3; TSC22D1; SPEN; IRF8
Down-regulation	186	SOHLH2; NR2F6; THAP4; ZNF682; PHIP; KAT2B; ID4; NFKB2; KLF10; ZNF43; CALCOCO1; IRF6; ESR1; ZNF44; RBPJ; ZNF611; GLI1; CSDC2; BACH1; JUN; ELF3; PCGF3; TRPS1; ZNF571; STAT2; NFE2L2; SMAD6; KLF3; OSR2; ZNF331; RORA; ACTL6B; ZNF257; ZNF117; MXI1; MEOX2; ZNF180; MYCL; USP21; CIC; ZNF112; MNDA; EYA2; ZNF217; ZNF329; TBX21; SIAH2; DBP; DACH1; LIMD1; THAP7; SMARCA1; MYCN; ZIM2; RARG; ZNF467; E2F2; PHF20; LIN28A; ZXDC; ZNF250; TCF7L2; ZNF623; ZNF444; IRF7; OVOL2; CBFA2T2; PRDM1; SSBP3; ZNF701; ERF; ERBB4; ZNF665; ZNF253; BARX1; SP110; ZNF423; FOXC1; ZSCAN31; SP100; EYA1; URI1; ZNF606; JAK2; ZBTB44; MBD1; DLX5; HDAC3; ZNF124; ZNF587; ZZZ3; TBL1X; ZMYND8; ZNF446; ELK4; TCF7L1; REL; ZNF85; NFATC3; PQBP1; NEUROD1; WT1; HOXB2; HOXC10; GRHL2; FOXN3; KAT6A; ZNF160; ZNF211; ZNF33B; CBX4; ZNF239; ZNF415; ZNF93; HBP1; ZNF264; WNT4; FOXK2; CREB1; GATA6; ZFPM2; ZNF136; GTF3A; HMGN3; ZNF443; ZNF273; KLF11; MXD4; CD3D; TXNIP; AR; PAWR; NR2F2; ARID5B; ZSCAN9; RREB1; BCL6; ZNF586; PIAS1; CARHSP1; MAF; MYBL1; TRIM24; ELF5; NR0B1; CREB3L2; CEBPD; NKX2-1; ARID3A; NR3C2; SOX2; NR2C1; ZBTB20; TCF7; E2F5; ZNF512B; HOXD3; IRX5; DMTF1; CITED2; PRRX1; ZNF544; ZNF562; ZBTB38; HMGA2; NCOA1; DAXX; CBX7; IRF9; BCL3; IKZF1; TWIST1; NFAT5; MECOM; MAFB; ZNF91; TOX; GATA2; TGFB1I1; TFAP2C; ID1; HHEX; GATA3; FOXG1; TRIM22; POU2AF1