Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76118	Tgx-221	GSE92742	MCF10A	Human	24h	10uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	150	KLF9; HDAC9; SAP30; TTF2; ZFP36L2; VEZF1; TDRD3; TAF9; YEATS4; ZNF12; ZNF143; NFATC4; LITAF; PHF8; ZHX2; HDAC6; RFX7; ATF2; HOXA6; ZNF532; POLR3C; NFYB; TEAD1; CCDC59; BRIP1; ILF2; EHMT2; FOXO1; SETDB1; ZNF84; FLI1; NFIX; ARID5B; CUX1; ZNF140; THRAP3; MNAT1; TRIM27; PMF1; SOX13; BTG1; HIF1A; MITF; ZNF432; ZNF165; ZNF195; ETV4; PBX1; RNF6; TAF4; ZNF232; RYBP; E2F8; TOX3; CRYM; SMAD5; ATF1; VPS72; ZFX; ZNF574; PNRC1; RNF138; ZNF91; SPIB; ZBTB11; TFAM; CSDE1; STAT6; HOXA10; UBE2I; MLX; FOXA1; NPAS2; TAF7; NCOA2; HOXA5; NCOR1; CERS6; RB1; HMGB1; MBD2; BRWD1; CUX2; KLF6; PEX2; MED17; ZNF117; EMX2; RBL2; TDP2; ETV1; BNC2; KAT8; NFE2L1; TCF21; COPS5; MED4; IFI16; TCEA1; CRY1; TWIST1; ZNF85; CTBP2; ZNF586; RAD21; ZNF394; ZNF83; THRA; BAZ1A; FOXA2; DMTF1; CBFB; MED13; PRKDC; EHF; CRK; ZNF544; ZKSCAN1; PCGF2; ZBTB18; ZNF217; PSMD9; SUB1; ETS1; CLOCK; ASH2L; SUZ12; TFCP2; TSC22D3; SAP18; CCNH; LOXL2; ACTL6A; MYRF; MEIS2; ASCL1; SMAD3; RFXANK; FOSL1; ARID4B; PBX3; PPRC1; SOX9; TCERG1; TSC22D1; ETS2; TLE1; ATF3; FOS; TRIM22
Down-regulation	112	DLX4; NFKB2; RORA; NFE2L2; SOHLH2; E2F2; NR4A2; PRRX2; PHIP; ZZZ3; HOXC11; TRIM32; ZNF536; SMARCA1; ETV5; XBP1; TFDP2; ZNF611; HMGXB4; NKX2-2; HLTF; PHF20; OVOL2; JARID2; HMGN3; PCGF3; MAF; FOSL2; ELF3; WWTR1; BHLHE41; SCAND1; KDM5D; KDM2A; ZNF835; TCF20; AHR; NFATC3; KLF10; CREB3L1; ZNF629; ZNF816; WNT4; ZBTB43; SOX11; SIAH2; RNF4; MAGED1; RCOR1; NR1D2; SERTAD2; GRHL2; HOXC10; PRDM2; HMGA2; ZNF331; TLE2; SPEN; CBX5; PHOX2B; SALL1; IRF5; ELF5; TCF7L1; ZNF160; ZFHX4; ATF4; MXD4; ARNTL2; HOXC6; ZMYND8; MAFB; ZBTB20; IKZF1; YBX1; HLF; MEIS1; TBL1X; ZNF512B; DAXX; ATF5; DLX2; TRPS1; KDM5A; CARM1; ZNF721; NFIB; STAT5A; SOX10; PEG3; FLNA; DLX5; ZIC1; KLF4; ZNF264; GATA3; ESR1; TCF4; BASP1; ID2; TGFB1I1; TCF7; TBX3; EGR2; FOXF1; TCFL5; KAT6B; HIC2; ZNF131; BIRC2; NR2F2; HHEX