Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76111	Pyrazolanthrone	GSE92742	MCF10A	Human	24h	2uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	181	SSBP2; CEBPZ; ZFP36L2; LEF1; ID2; HINFP; RXRA; ZNF468; TBX2; PRRX2; ESRRG; KLF9; PDLIM1; HIVEP1; PMS1; ZBTB25; TAF9; THAP3; NFYB; ZNF202; MXD1; LZTS1; IKZF5; ZFX; POU5F1B; LHX6; HNF1A; SMARCA5; ZNF302; MYCN; PRMT2; ZNF83; ZNF423; ZNF14; CBX3; PHF20; HCFC2; BANP; MED20; NFATC1; ZNF415; NPAT; IRX4; RBL2; ZNF93; MAF; ZNF84; PHF1; TXNIP; BRD3; RREB1; MNT; IKZF1; ZNF211; HDAC4; ZNF764; PEX14; BCL11B; KDM5B; RRN3; MAML1; AEBP1; SERTAD2; MYT1L; ZNF654; ID3; STAT4; LITAF; SPEN; MDFI; ZBTB11; ZBED1; ZNF91; SIX3; MED7; HSF2; TRAK1; NR2F2; SP140L; ZNF253; GATA3; NLK; STAT1; MEOX2; TDP2; ZNF184; ZEB1; ID4; TCF3; IL16; ZEB2; PIAS4; MEF2A; SLC2A4RG; HOXB2; KLF7; ARID4B; NFRKB; STAT3; BRD2; HMGB1; ELF2; BTG1; NR2F6; ATF5; UBE2L3; GFI1; SATB2; NCOA1; REPIN1; NR3C2; ZNF43; HOXB7; SMARCE1; BACH1; SMAD1; ZFHX4; PBX1; MTA1; BBX; STAT5A; ZNF140; ZNF134; DNAJC1; TOX; CCNE1; PRRX1; ZNF22; BATF; BCL6; USF2; BIRC2; CTBP2; CHD1; TLE1; SCAND1; HTATIP2; PBXIP1; TCFL5; ENY2; ZNF85; ZSCAN18; UBE2B; IRF7; FOXF1; BMI1; SPDEF; ZNF443; RB1; NFE2L1; ZNF562; ZNF586; FOXC1; POU2AF1; PSIP1; PAXBP1; FOXO1; KLF6; MAX; TCF4; AHR; CREG1; IKBKAP; DMTF1; THAP11; HOXC6; TGIF1; EDF1; PBX3; SOX9; MYB; EMX2; IRF8; DAXX; MSX1; TOX3; IRF4; TSC22D1; SNAI2; FOS; MEIS2
Down-regulation	200	NKX2-1; FOXL2; IFI16; XRCC6; CDK2; CBX5; WDR77; MNAT1; TADA3; SMARCA1; TRIM33; NCOR2; TEAD4; ZNF74; ZBTB16; SSRP1; CCNT1; ANKRD1; ZNF274; TAF10; TFE3; MYBL1; SUPT5H; TSG101; HOXD11; TRIM27; NR4A1; HDAC6; CALR; HDAC7; FOXE1; RFC1; GATA4; PKNOX2; DR1; ZNF556; CALCOCO1; ZBED4; SMARCD1; CNOT3; SREBF2; TSHZ2; TFCP2; RHOA; TCF20; PAX6; SSX1; CITED2; DDX5; NCOA3; HDAC1; MED14; POU4F2; MEF2D; PSMC3; THAP10; SOHLH2; SMARCC2; HLF; TFCP2L1; RBPJ; HOXA11; CTR9; ENO1; NEUROD1; HIPK3; POLR3C; RBPMS; NFATC3; NONO; LIMD1; WT1; SIM2; ZNF410; ZNF768; BTF3; MAFF; BAZ1B; PPP1R13L; ZFP69B; MYRF; HMGXB4; ZNF432; LMCD1; TAL1; MGA; RCOR1; NFE2L3; MED6; NR4A3; ZBED2; PGR; SMARCC1; ELF3; JUND; PBX2; ATF3; PARP1; MED15; SND1; MED24; YBX1; FOSB; ETS2; TRIM16; RING1; CCNC; TRIM28; NCOA4; ATF6; ZNF430; GTF2IRD1; SMARCB1; CUX2; RBFOX2; ZSCAN31; IRF9; ZNF576; EGR2; STAT6; ADNP2; TCEA2; CCNH; PITX1; USP22; ZNF787; ZNF131; DDX17; EHF; MTF2; RNF4; TRIP6; TAF7; NHLH2; NR1H2; NR1I2; BHLHE40; FOXA2; MNDA; PIR; ATF4; HIPK1; TLE2; MED13; ESR1; REL; NR4A2; RELB; FOSL2; CNOT2; PRKDC; KAT6B; MDM2; HOXD10; ZNF580; FOXO3; BAZ2A; SIAH2; WWC1; BNC2; TWIST1; TERF1; ZMYND11; CLOCK; COPS5; SATB1; SUZ12; COPS2; CRK; BAZ1A; HHEX; ZNF593; PFDN5; ZFPM2; ZBTB20; ARNTL2; TRIM24; PCGF2; CREB3L2; ELF5; HIRA; ATF1; EZH2; RBBP8; RFXANK; FOSL1; ABL1; KDM5D; PEG3; PAWR; HOXA10; CEBPA; NKX3-1; KLF4; SMAD3; SUV39H1; ZBTB18; ID1; TBX3; BASP1