Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76088	Pf-477736	GSE92742	MCF10A	Human	24h	10uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	165	TAF10; HDAC6; HDAC9; ZNF432; PHF8; BTG1; MED1; NCOR2; ZNF226; FOXO4; HCFC2; RFX7; STAT6; MLXIPL; EGR1; DDIT3; ZFP36L2; MTF1; TTF2; POU3F2; CRY1; ZBTB16; ATF1; SOX15; KLF9; SIRT7; TOB1; DRAP1; ZNF143; SIX2; UIMC1; YEATS4; BCL10; YAF2; EGR4; CREB5; ERBB2; NRBF2; TSC22D2; MLX; SP2; MNAT1; TEAD1; AATF; RYBP; RNF111; HTATIP2; TRIP6; SAP30; HIVEP2; FOXA2; PSMD9; CCDC59; PHF2; TAF9; CREB3; KLF6; ZBTB7A; TBX10; CSDE1; ISL1; UBE2I; NRIP1; CHD9; SP110; ARID4B; BAZ1A; CUX2; FOXA1; TFAM; RNF6; SMAD5; NEDD8; PBX3; ZNF140; BRD8; BRD2; FOSL1; JARID2; SOX9; CRK; MED27; TSG101; PMF1; ASH2L; SETD2; KAT5; CREB3L1; BAZ2A; MED17; HOXA5; SIM2; NR2E1; CUX1; BRF2; TSC22D3; UBE2B; EP400; MDM2; KLF5; INSM1; NFE2L1; BAZ2B; LITAF; USP22; ASCL1; KLF7; MED13; RUNX1; TOX3; SAP18; XBP1; HMGA1; NPAS2; C1D; DNAJC1; SCAND1; INSR; ATF4; ING3; MITF; SMAD3; CRYM; NKX3-1; ELF1; STAT1; PBX1; COPS5; HMBOX1; TCEB2; RB1; EDF1; TSC22D1; PCGF2; YWHAB; GABPB1; CLOCK; PTTG1; PFDN5; LOXL2; DMTF1; PRKDC; ETS1; SUZ12; CBFB; SREBF1; NFATC3; PITX1; BMI1; TLE1; ATF3; TAF1D; FOSB; ZNF91; FOXG1; RFX5; BASP1; TRIM29; FOS; ATF5; TCERG1; MSX1; IKBKAP; CEBPB; TRIM22
Down-regulation	168	SP3; NFE2L2; TGIF2; FOXL2; CDK2; NFKB2; DNMT3B; ZNF611; PHIP; DLX4; ID4; SFMBT1; TFAP2A; TFDP2; PARP1; SP140; SMAD6; ZXDC; WT1; ZNF665; ZNF571; HLTF; FOXE1; NFATC1; TEAD4; LIMD1; ZNF180; TULP4; CALR; TCF4; SMARCA1; ZNF329; HHEX; WWTR1; FOXM1; ZNF211; ZNF331; RARG; REL; HOXC10; GRHL2; ZNF701; TEAD3; ZNF74; ZNF551; ZFPM2; BHLHE41; PRDM2; ZNF264; ATN1; HMGXB4; GTF2I; DBP; NR4A2; ZNF227; ZNF134; HMGN3; NHLH1; ZNF587; URI1; PAX6; RBL1; NFE2L3; ZNF816; ZNF253; ZNF44; TFAP2C; RORA; CAMTA1; ZEB1; TCF7L2; TGFB1I1; RUNX3; ESR1; CBX4; TLE2; E2F2; DACH1; HMGB2; AR; ZFP36L1; ZNF544; BCLAF1; CTCF; ELF3; HOXD3; ZSCAN31; SOX17; EN1; SOX10; HEY2; MNDA; POU4F1; ZNF586; ZNF43; ZNF835; SIAH2; HOXD1; CCNA2; ZNF606; ZBTB20; SLC2A4RG; TCF7L1; HLF; MXI1; IRF6; KAT2B; ZNF239; FOXF2; NR1H2; ZNF273; MYBL1; IRX5; OSR2; CREM; PITX2; ZNF512B; SHOX2; ARID5B; OVOL2; MAF; PAX5; PBXIP1; HOXC4; MYCN; ZNF419; SOX11; WNT4; CCNE1; ZNF160; IKZF1; TRIM28; MYCL; DLX5; IRF4; ZNF22; CBX7; CREB3L2; FOXC1; MYB; ZBED2; ZNF467; DAXX; PIR; HOXC6; TBX2; CREG1; BCL3; ERBB4; ZSCAN18; ZNF443; ZHX2; CEBPA; STAT5B; AHR; IL16; GATA2; TRPS1; TBX3; SALL1; EGR2; TOX; FOXF1; PEG3; GATA3; HIC2; POU2AF1; TXNIP