Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76087	Pf-431396	GSE92742	MCF10A	Human	24h	0.08uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	165	TAF10; HDAC6; PCBD1; MED1; PHF8; AATF; ZNF432; HTATIP2; SMARCA2; TTF2; HSF2; HCFC2; PIAS2; MLXIPL; NCOR2; BAZ1A; MNAT1; CRY1; ZMYM2; ERG; RNF6; ATF1; FOXO4; STAT6; MLX; RFX7; SOX15; HES1; ELK1; RELA; ZNF226; TMF1; FOXI1; ZNF143; SMAD1; CCDC59; USP22; BATF3; HDAC9; HOXA5; PHF2; TFAM; TBP; ADRB2; YAF2; TSC22D3; MTDH; ZSCAN5A; ELK3; CHD9; NRIP1; ARID4B; BAZ2B; YEATS4; TAF4; BAZ2A; PCGF2; RFX5; CTR9; UIMC1; ETV1; ASH2L; MAZ; PEX2; PSMD9; SMAD2; C1D; MBD2; TSC22D1; CUX1; HOXA7; BMI1; SETD2; ZNF576; CBFB; NEDD8; CITED1; PTTG1; BRF2; TSC22D2; ING3; HOXA10; MED6; KAT8; DPF2; NPAS2; NR2E1; NCOA3; SMARCE1; UBE2I; TSG101; ZNF131; FOSB; KAT5; PMF1; MED23; TFEB; TCFL5; KLF6; MED4; GABPB1; CRK; HEY1; LITAF; BRD8; ID3; ECD; TLE1; TFEC; RYBP; HDAC1; ZBTB11; VDR; ACTL6A; STAT3; ZNF274; MMS19; FOXO1; CLOCK; CTBP2; SNW1; TRIP6; TOB1; TCERG1; RUVBL2; IKBKAP; SFPQ; FOXA2; DDIT3; STAT1; SAP18; SIX2; BTAF1; PRKDC; CCNC; SOX4; MEOX1; EMX2; AIP; MITF; KAT2A; MYCBP; TRIM29; SUZ12; RFXANK; SCAND1; HMGA1; LOXL2; CREG1; ZNF83; RUNX1; SIX1; MAFB; SUB1; ID2; TCEB2; ASCL1; KLF5; PSIP1; JUP; MTF2; FOS; MSX1; SNAI2; HOXC6
Down-regulation	180	NFE2L2; NFKB2; RORA; PCGF3; TGIF2; DLX4; GTF2I; EYA1; FOXF2; ID4; ARNT2; TBX21; SP3; ZXDC; NEUROD1; SMARCA1; ZFPM2; ZNF571; MNDA; ZNF611; CDK2; DAXX; OSR2; ZNF44; ZNF331; CALCOCO1; BACH1; NANOG; HMGB2; TCF7L1; ZNF665; SOHLH2; TBL1X; ZNF711; FOXL2; CREB3L2; ZNF701; MYBL1; FOXM1; LIN28A; SSBP3; RARG; OVOL2; ZNF253; STAT2; KAT2B; ZNF654; FOXE1; NR4A2; KLF3; PRDM1; TEAD3; ERBB4; VGLL1; URI1; CAMTA1; ZIC3; ZNF117; TULP4; CBX4; TCF4; PRDM2; ZNF43; ZNF74; PHIP; NKX2-1; ZIC1; ZNF264; FOXF1; ZNF816; ZNF75D; KDM5C; EPAS1; ZBTB17; TFAP2A; NFATC3; ZNF180; CBX7; PAX6; DBP; CALR; ZNF423; NR1D2; DLX5; NHLH1; HEY2; GATA6; HHEX; MED12; DACH1; ZNF536; HIC2; ZNF239; ZNF248; MAF; CREM; TBX3; BHLHE40; IRF1; ARID3B; E2F2; ZNF444; TFDP2; ZNF273; HMGA2; ARID5B; TGIF1; RREB1; HOXC10; RBFOX2; CD3D; SOX2; UBTF; CNOT3; ZNF415; TRPS1; GRHL2; CITED2; DLX2; SOX10; FOSL2; ZNF586; ZSCAN9; SMAD6; EP300; PHOX2B; IRF7; ZNF580; PEG3; ESR1; SATB1; NR4A3; PRRX1; IRF6; SOX5; NR3C2; WNT4; KLF10; TGFB1I1; FLNA; MEIS2; ZNF512B; HSF1; HIRA; SOX11; HOXB2; SIAH2; WT1; BHLHE41; HOXD3; NR2F1; REL; ING2; SALL1; CARHSP1; EYA2; GATA2; ZEB1; AR; TLE2; ZNF266; NR1H2; ZNF160; TBX2; IRF4; IRF9; ELF5; SPEN; TFAP2C; IKZF1; TGFB1; KLF4; PAWR; IRX5; AEBP1; EGR2; GATA3; TXNIP; ATF3; POU2AF1