Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76086	Pf-431396	GSE92742	MCF10A	Human	24h	0.4uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	180	TAF10; RSF1; HDAC6; TTF2; HDAC9; TMF1; MED1; PHF8; HSF2; PCBD1; RFX7; ORC2; HCFC2; CRY1; SMARCA2; TDRD3; ELK1; FOXO4; MLXIPL; EED; NRBF2; MNAT1; TOB1; HOXA6; AATF; EGR1; YEATS4; TSC22D3; RNF6; TFAM; ING3; MTDH; BAZ1A; KLF6; ZNF432; ATF1; MAZ; MED6; PRKDC; NCOR2; BTG1; ZNF143; C1D; DDX5; TTF1; TBP; PMF1; HOXA5; PHF2; HTATIP2; MED17; SAP30; GTF2A1; TRIP6; EGR4; PIAS2; CCDC59; SMAD2; PCGF2; REST; MLX; SIX2; HMGA1; STAT6; PATZ1; SP2; PEX2; BRF2; USP22; ZNF557; MED4; ETV1; NFIL3; ASH2L; EHMT2; TSC22D2; BCL10; HIVEP2; MTF2; VEZF1; COPS5; NFYB; ELF1; BAZ2A; TFCP2; WDR77; GABPA; THAP1; CERS6; YAF2; ZNF195; ZNF468; TGS1; NR1I2; ID3; HEY1; KMT2B; NEDD8; USF2; MED21; RYBP; CTR9; BAZ2B; CRK; ZNF669; FOSB; PSMD9; ARID4B; RBBP5; AFF1; MED24; ZMIZ2; ZFP36L2; SOX15; ZBTB32; ETS2; FLI1; ZNF394; RCOR3; STAT3; NPAT; ILF2; RFX5; PBX3; ZNF165; HOXA7; CRYM; JARID2; TLE1; XRCC6; MBD2; ZBTB18; MED23; CBFB; TSC22D1; ZBTB11; KAT5; VGLL4; SFPQ; NLK; ECD; GABPB1; SREBF1; BMI1; SAP18; CHD7; MYCBP; MAFB; TCFL5; ACTL6A; MED13; FOXA2; SSX1; ZNF274; LITAF; FOXO1; BACH2; BRD8; VDR; ID2; RHOA; IKBKAP; EMX2; MEOX1; HLF; EZH2; PTTG1; SCAND1; JUND; SIX1; SUB1; SUZ12; SOX9; TCERG1; MYB; HOXB6; PDLIM1; ZBED2; FOXG1; FOS
Down-regulation	150	PHIP; PCGF3; SOHLH2; NEUROD1; PAX6; NFKB2; ID4; SMARCA1; TBX21; ARNT2; NFE2L2; TGIF2; DLX4; DAXX; EYA1; MNDA; CBFA2T3; ZIC1; FOXF2; HMGB2; E4F1; VGLL1; ZNF74; WWTR1; BARX1; RBPJ; ZNF500; THAP7; RARG; RBFOX2; ZXDC; E2F2; FOXM1; ZFP36L1; IRF1; DLX5; ZNF816; ZNF133; GRHL2; FOXF1; NR1H3; ZNF117; HHEX; KAT2B; OSR2; CBFA2T2; KLF3; PRDM2; CTBP1; ZFPM2; ERBB4; TULP4; ZNF253; ZNF512B; HOXC11; CALR; TEAD3; RORA; LOXL2; ZNF623; SMAD6; PURA; ZNF536; HLTF; NFATC3; TLE2; ESR1; TGFB1I1; ST18; ZBTB20; ZSCAN32; SOX10; ZNF239; ZNF180; TBL1X; PRDM1; CREB3L2; TFDP2; TFAP2C; CREM; IRF6; SOX2; JAK2; POU4F1; NR4A2; CBX4; MYBL1; NKX2-1; SATB1; ZNF835; ZNF331; ZNF415; CD3D; DBP; ZEB1; HIC2; CBX7; ARID5B; TCF4; ZNF324; EP300; MEIS2; ZNF264; EN1; HOXD1; TXNIP; SOX5; SOX11; OVOL2; ZNF586; ZNF423; IRF7; ZNF587; IRF3; PHF20; ZFHX3; AR; PEG3; REL; MECP2; FOXC1; ZNF419; HOXC10; TGIF1; PRRX1; TRPS1; JUP; SALL1; SHOX2; ATF4; ZSCAN18; NCOA1; CITED2; DLX2; ING2; HIRA; IRF9; NKX2-2; NFAT5; TWIST1; DMTF1; ELF5; TBX3; GATA2; GATA3; BCL11A; TOX; IKZF1; TGFB1; WT1