Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76085	Pf-431396	GSE92742	MCF10A	Human	24h	2uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	207	TAF10; ID3; PHF8; HDAC6; NCOR2; PCBD1; TSC22D4; MED1; TRIP6; FOXO4; LEF1; MNT; HDAC9; CRY1; MLXIPL; STAT6; TTF2; DDIT3; DDX5; CERS6; UBE3A; NR1I2; CREB3; TSC22D3; ZNF432; PIAS2; RFX7; HOXA5; ERBB2; MLX; SAFB2; TRIM29; TMF1; BRPF1; TAF7; IKZF5; BTG1; ETV1; ATF2; ZNF165; TWIST1; PATZ1; NRBF2; RFX5; SAP30; SMARCA2; ING3; HEY1; EGR1; ZFP36L2; MTF2; TADA3; MED27; USP22; TAF9; SMARCD2; BAZ1A; ZNF302; TEAD1; HTATIP2; ZNF140; ATF1; PMF1; CHD9; ZNF91; MTDH; NRIP1; TSC22D2; RYBP; HAND1; LITAF; BAZ2B; RRN3; CCDC59; KAT8; TFAM; BAZ2A; MED24; SMAD2; FOXN2; ZNF426; ERG; VEZF1; PTTG1; YAF2; ZNF8; CUX1; KLF9; FOXO1; MAFF; MMS19; CBFB; ZBTB7A; BTAF1; ZNF394; ARID4B; MAZ; ZNF468; ZNF189; PRKDC; CRK; TLE1; TRAK1; NR2E1; BACH2; PSMD9; YEATS4; JARID2; NFIL3; TCF12; PEX2; ZNF131; DPF2; ZNF274; ZNF532; MED13; IRX4; SOX15; VDR; KAT5; COPS2; HOXA7; CITED1; CCNC; ID1; ELF1; TOB1; ZKSCAN1; GTF2IRD1; IFI16; FOSB; MLXIP; ZNF544; UBE2I; PBX3; RFXANK; SOX9; BMI1; TRIM16; MAFB; CTR9; ZNF304; JUND; NEDD8; MITF; CTBP2; FOXD1; TCEB2; CHD7; SREBF1; BIRC2; HDAC1; ZNF83; DNAJC1; TBP; IKBKAP; PCGF2; KLF5; SMAD1; CNOT2; KLF7; CEBPG; ZNF587; EMX2; ZHX2; HMGA1; SIX2; RUNX1; SAP18; AFF1; SMAD7; KLF2; TCERG1; TFCP2; ZNF267; ZBTB11; AEBP1; NR2C1; ZMIZ1; SOX4; NCOA4; SUZ12; ASH2L; VGLL4; C1D; ELK3; LOXL2; BRD8; PAX5; AIP; CREG1; MSX1; CLOCK; RUVBL2; FOSL1; ZNF586; SIX1; PITX1; ATF3; ID2; PFDN5; SCAND1; HOXB6; BASP1; TSC22D1; ATF5; ZBTB18
Down-regulation	158	JUN; NFKB2; SP3; RORA; PCGF3; KAT2B; SOHLH2; NFE2L2; SMARCA1; ZNF571; MYCL; PHIP; ZXDC; TAF1A; HMGXB4; THAP7; CDK2; RBPJ; MNDA; DAXX; PAX6; GRHL2; FOXM1; ZNF623; FOXF2; SP100; NKX2-1; TEAD3; KLF11; MYBL1; CREM; ABT1; NR1D2; OSR2; E2F2; ZFP36L1; FOXJ2; AR; GCFC2; CAMTA1; CENPF; VGLL1; TBX21; ZNF331; NANOG; NR5A2; SUMO1; EN1; PLAGL1; ZNF654; ZNF180; MAF; PRDM2; ZNF248; ELF5; CALR; NEUROD1; TCF7L1; ELF2; CBFA2T2; SP140; ETV5; LIN28A; URI1; ZNF74; ZNF124; TULP4; ZNF512B; ERBB4; TEAD4; HEY2; HLF; SSBP3; PRDM1; DLX5; WT1; RBL1; CBX7; PSPC1; ZNF536; SOX10; FOXF1; EYA2; CBFA2T3; CREB3L2; NR4A2; YEATS2; EPAS1; SIAH2; BCLAF1; ZFHX3; FOXE1; CCNE1; RARG; NKX2-2; PHF20; TRPS1; DBP; NFE2L3; GATA6; HOXD1; TBL1X; TCF7L2; NCOA1; FOXC1; KLF3; ZNF148; HHEX; HOXB2; NFATC3; OVOL2; ESR1; ZNF117; CD3D; IKZF1; CBX4; ZNF467; HIC2; IRF6; RREB1; BHLHE41; HLTF; STAT4; TGIF1; IRF7; WWTR1; SLC2A4RG; IRF4; CITED2; PRRX1; CREB1; NFYC; TLE2; NFAT5; MYCN; AHR; TFAP2C; SOX17; SHOX2; PEG3; TXNIP; SOX11; KLF10; SOX2; ELF3; TGFB1I1; ZFPM2; HOXD3; ID4; PAWR; TBX3; KDM5D; BCL11A; NR1H2; GATA2; NR2F1; CBX6; GATA3