Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76084	Pf-431396	GSE92742	MCF10A	Human	24h	10uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	191	TAF10; HDAC6; PHF8; FOXO4; TSC22D4; TSC22D3; SMAD2; SMARCA2; TRIP6; NCOR2; PATZ1; TOB1; KLF9; TADA3; TTF2; PCBD1; HDAC9; ZBTB7A; RFX5; LEF1; ZMYM2; MAZ; KDM4A; HIVEP2; ADRB2; RFX7; DDIT3; RNF6; AATF; HMG20B; PHF2; MED1; PRKDC; MLXIPL; RELA; FOSB; ELK1; KAT7; SAP30; STAT6; DDX54; SMARCD2; HDAC1; TDRD3; FOXO3; BAZ1A; BCL10; HOXA5; TSC22D2; MTDH; BRPF1; NRIP1; TSG101; ARID4B; ATF1; SOX15; HTATIP2; NFE2L1; ELF4; EGR1; ETV4; SAFB2; FOXO1; PSMD9; ID3; KLF5; USP22; CENPF; ERBB2; MMS19; MNT; HMGA1; TP63; DDX5; TLE1; MED13; GTF2IRD1; JARID2; NRBF2; HOXA1; PMF1; CTR9; NCOA3; HSF2; BRD8; BAZ2A; PTTG1; BTAF1; SAP18; MED24; NR1I2; EHMT2; SND1; ELF1; SIX2; SETD2; SMAD3; ZNF143; BMI1; TBP; NFKBIA; TRRAP; BACH2; VEZF1; UIMC1; ING3; MBD2; BRF2; TFEB; KAT5; PBX3; MED15; ZNF432; HOXA10; BASP1; ETV1; DPF2; HEY1; RNF10; MAFG; TRIM29; CCDC59; MLX; NFIL3; KLF7; TRAK1; TCEB2; STAT3; NR2E1; TWIST1; EP400; ZNF189; KAT8; CRK; CREG1; KMT2B; LOXL2; RELB; USF2; BCL11B; EMX2; AIP; ELK3; PNRC1; ASH2L; PFDN5; ZNF281; CUX1; NELFB; MED4; CTBP2; CTNNB1; RFXANK; UBE2B; SNW1; PIAS3; C1D; PCGF2; MITF; TSC22D1; SOX4; LITAF; ZBTB18; SREBF1; EDF1; CCNC; ABL1; MED23; TFCP2; IKBKAP; KLF2; E2F3; MEIS1; TLE4; VGLL4; CHD3; NCOA4; SCAND1; HOXC6; STAT1; TCERG1; RBPMS; PBX1; KLF6; SUZ12; MSX1; PSIP1; SMAD7; FOSL1; ATF3; SNAI2
Down-regulation	160	NFE2L2; ZNF571; NFKB2; MNDA; PCGF3; ID4; FOXF2; PAX6; GTF2A2; ZNF331; ZNF253; ZNF43; ZNF711; TFDP2; ZNF682; ARNT2; CREM; RORA; PLAGL1; CAMTA1; VGLL1; ZSCAN31; MYCL; ZNF180; CBFA2T3; KAT2B; NOC2L; ZNF512B; ZNF239; ZXDC; ERBB4; RXRG; ZNF623; SOX11; SUMO1; ZNF117; SMARCA1; ZNF44; GTF2I; ZNF273; BACH1; NEUROD1; ZKSCAN7; TRPS1; NKX2-1; ZNF329; BATF3; HLF; CREB3L2; PRDM2; ZFPM2; BANP; GATA6; ZNF551; RBPJ; ZNF175; TRIB3; CERS4; ZBTB20; NR4A2; PHIP; HMGA2; PEG3; ZNF816; ZNF415; ZNF665; ZNF136; HHEX; KLF10; LMCD1; ZNF248; KLF3; FOXF1; E2F2; IRX5; NR4A3; ZNF124; TCF4; URI1; SP140L; SOX10; CBX4; TOX3; AR; RARG; TEAD3; ZSCAN9; CD3D; ZNF264; NR1D2; FOXE1; WWTR1; GRHL2; CCNE1; POU4F1; NFATC3; WT1; ZNF85; ZNF586; BCLAF1; BHLHE41; PRRX1; ELF5; TCF7L2; TBX3; SOX2; ZNF134; SLC2A4RG; KLF11; RAD21; OVOL2; ZNF22; TRIM24; HOXB2; RBFOX2; NCOA1; ST18; ELF3; SOX5; CNOT3; TLE2; AHR; TAF9B; NKX2-2; ZSCAN18; OSR2; IKZF1; DLX5; ESR1; ZNF107; FOXC1; DBP; ZEB1; EN1; ZNF266; TFAP2C; SATB1; HIC2; MEIS2; HLX; CREB1; CEBPD; DLX2; ZNF562; DAXX; HOXD3; IRF7; MAF; EGR2; NR2F1; IRF4; CBX7; E2F6; GATA2; DMTF1; TOX; TXNIP; TGFB1I1; CBX6; GATA3