Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76076	Ibrutinib	GSE92742	MCF10A	Human	24h	0.08uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	137	KDM4A; SMAD2; RNF2; TP63; BANP; MAFF; ZEB2; SMARCA2; SAP18; TCF25; KDM4C; UBE3A; NFYA; PHF2; BCL6; HTATIP2; KLF2; LPIN2; CREB3; TDRD3; NR4A3; SIX2; TERF2; RELA; PHOX2B; MEIS1; TADA3; ERG; CHD9; DACH1; RNF14; HMGA1; PRMT2; ELF3; TOPORS; PQBP1; TSC22D3; STAT2; MYT1; SUPT3H; RING1; SF1; HES1; PMF1; RXRA; HMGB1; ZMYM2; RNF6; SREBF1; ELF1; GTF2F1; MTA1; JAK2; TFEB; CREG1; CDYL; SOX4; AES; ZNF423; BMI1; ESRRG; RRN3; MDFI; TOB1; CDC5L; NRIP1; ARID4B; RFX5; NR4A2; TRIM16; ATF3; RCOR3; AHR; TAL1; ETV5; ZNF574; NFATC1; RUNX1; SUPT7L; DDIT3; NCOA2; SNAI2; CRYM; SNW1; MKL2; MED4; NFE2L3; PSMC3; BACH2; NR2F1; LEF1; TSC22D1; GATA3; BAZ1A; TCEA1; PSMD9; BHLHE41; ZNF131; BIRC2; JUP; EDF1; MED1; CUX2; TRIM29; PRRX1; KAT6B; ESR1; ZFPM2; SHOX2; KLF5; ATF1; NCOA1; RFXANK; EGR3; ZNF281; BRCA1; NKX3-1; TWIST1; TLE1; COPS2; PBX3; SMAD3; CREBL2; TCF7; TERF1; C1D; JUNB; SCAND1; IRF7; SATB2; BCL11A; ELK3; CREB1; SOX9; EGR2; SATB1; MAFB
Down-regulation	153	ZBTB16; WWTR1; CEBPE; NKX2-5; HMGB2; THAP4; SMARCD3; ZNF778; ID4; RBPJ; SMARCA4; ZFP36L2; ZNF84; PEG3; CREB3L2; ZNF165; SAP30; DAXX; NKX2-1; ANKRD1; RAX; CITED2; YBX2; LMCD1; VGLL1; GFI1; MYOD1; ZNF711; ETS1; CENPF; PHIP; CTBP1; ZIM2; PCGF3; GLI3; ZNF133; TAF1A; SCMH1; TEAD1; MLXIP; RFC1; TCF7L1; ARNTL2; CARM1; SOX3; EN2; ARID1A; FOXF1; ZNF652; TFDP2; SPEN; FOXK2; USP22; BHLHE40; ZNF224; RBPMS; TBL1XR1; NANOG; NFATC3; KAT6A; CDX1; ZNF667; RNF4; TFCP2L1; ZNF248; CALR; NKRF; TAF1; TBL1X; ZNF12; ZSCAN9; FOXF2; BAZ1B; ZNF419; TRIM28; POU4F1; OSR2; CCNA2; MED12; PRDM12; ARID3B; ZNF787; PLAGL1; SMAD6; CNOT3; GATAD2A; NR3C2; PAWR; GATA6; TRRAP; ZBED4; BRF2; FUBP1; NFIB; FLNA; CDIP1; ZNF580; IFI16; PITX2; ZNF329; MECP2; WWC1; TCF12; ZNF551; BRD7; ATF5; AGO2; MITF; ELF5; CD3D; ZNF304; RAD21; FOS; SALL2; MAFG; ENY2; ARID3A; TOX; VPS72; PITX1; CCNH; CRK; NR1H2; JARID2; DLX5; CEBPD; E2F5; WT1; HSF1; SPDEF; SOX2; NR2F2; YWHAB; ZSCAN18; IL16; ABL1; TCFL5; THAP11; PAX8; ZBTB18; TOX3; HOXA10; ZNF586; HMGB3; CBX6; HHEX; TRPS1; MSX1; MEIS2; FOXG1; ID1; BASP1; TBX3