Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76075	Ibrutinib	GSE92742	MCF10A	Human	24h	0.4uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	93	ERF; BARX2; TRIM16; BACH2; TRIP6; STAT4; TP63; PAX5; ZIC1; TSC22D3; CUX1; ZNF394; HTATIP2; NFYA; BCL6; ZNF467; ZNF195; PATZ1; CCDC59; SMARCD3; ZBTB24; LDB1; PHF1; ZHX2; EHF; PFDN5; CERS6; CBFA2T3; PCGF2; YEATS4; RNF138; ZNF12; BCL11A; MECOM; ARID4B; CREM; PLAGL2; TFEB; GATA3; LITAF; TCEB2; ZBTB11; ZNF692; HDAC1; CREG1; PBX2; TCF25; FOXO3; HIPK3; REL; ECD; KAT5; PAWR; CHD3; RBL2; CEBPA; BRD2; KDM5D; TLE4; ZBTB1; NCOA4; CTR9; CCNH; BAZ2B; KAT8; ZNF586; LEF1; IRX5; TAL1; RBBP8; ZNF423; SUZ12; FOXJ3; CNOT2; ETS1; TRIM29; ID1; VDR; TCFL5; SATB1; CITED2; CRK; ASCL1; NFATC3; SCAND1; ZNF91; FOXG1; CREB1; TRIM22; EMX2; MEIS2; FOS; BASP1
Down-regulation	128	CALR; SOX9; ZNF23; MNAT1; ERG; ARNTL; ZBTB16; ID4; ZEB2; ST18; THAP10; HOXB2; MED12; PTRF; ZNF536; ZBTB20; TEAD4; NFIB; KDM5C; ZKSCAN7; NR1D2; ZNF227; HDAC4; ZNF500; HMGB2; RBL1; UBE3A; LMCD1; RBBP7; PIAS1; TCF21; EZH1; BHLHE41; ID3; SMARCB1; WWTR1; ATF7IP; RAD21; ZNF410; ATF5; ING1; HEY2; KLF10; MAF; MTDH; SMAD1; SP100; NR2F2; BLM; LOXL2; WWC1; ZNF44; MLXIP; MED15; PBX3; ZBED2; IKBKAP; GATA6; BCL10; MGA; ELF1; NR3C2; FOSL1; ELF3; ZNF32; GFI1; MAGED1; SPEN; ZNF22; ABL1; ZNF266; MNDA; UBTF; ZNF443; ZNF573; PEG3; EGR3; TGIF1; AHR; TCEA1; HHEX; CENPB; MTF2; TBX3; OSR2; RBPMS; WWP1; ELK3; ETV5; NR4A2; BRD8; HOXD3; ZNF302; KAT6B; BRCA1; DBP; BBX; MSX1; SUB1; ENY2; STAT5A; ZNF131; ZMYND8; MECP2; HOXC4; FLNA; AEBP1; JUNB; TSC22D2; ZFPM2; SOX10; DLX2; SUV39H1; THAP11; TLE1; GATA2; SMAD3; WT1; SIX1; TCF4; ZEB1; TGFB1I1; ZBTB18; PBX1; HOXB6; EGR2; MAFB; IKZF1