Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76074	Ibrutinib	GSE92742	MCF10A	Human	24h	2uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	146	TP63; MLLT10; EVX1; CHD9; PTRF; HSF4; CALCOCO1; TRIM29; TSC22D3; ID3; TRIM16; ZNF76; TCF15; NR4A2; ZNF423; ELK4; ZNF611; PPP1R13L; TDRD3; JUNB; RXRB; EPAS1; HDAC9; NR4A1; SUPT3H; KLF9; FHL2; CSDE1; TAL1; SMARCA2; PITX1; ERF; DACH1; EZH1; SMARCC2; ZSCAN31; ZNF506; SOX17; PPARGC1A; ZBTB20; LEF1; ZMYM2; SMAD2; CLOCK; ZKSCAN1; FLI1; SETDB1; PRKDC; ZNF426; RERE; STAT6; ID1; BCL11A; ZNF83; HOXB13; ZNF665; CDX1; LPIN2; SP2; CBX5; TBL1XR1; TSC22D1; MTA1; FOSB; BAZ2A; ERCC3; ELF1; RNF6; BNC2; SAP18; RFXANK; SUPT7L; ERBB2; MZF1; ZNF652; FOXN3; NR3C2; NRIP1; FUBP1; SNAI2; RFX5; MAFF; CUX1; NPAT; BHLHE41; PBX2; TLE4; MED24; CREG1; ZNF91; JUP; IFI16; CDK9; MEF2A; AES; ESRRG; ZNF117; SOX4; ZMYND8; NR1D2; TGFB1; IRF6; TERF1; GTF2IRD1; PDLIM1; MTF2; FOSL2; ZNF302; MYB; NELFB; BACH2; ZNF160; WWC1; CITED2; NCOA2; TLE2; KAT2A; MED1; FOXC1; THAP11; HOXA5; TLE1; HEY1; TCFL5; KLF5; RBL2; STAT1; WNT4; LITAF; ZIC1; CRK; ZSCAN18; SCAND1; HES1; ZNF131; KLF13; SOX9; MECOM; NR1H2; ABL1; ZNF721; RUNX1; HOXD1; FOXF1; MEIS2; TRIM22
Down-regulation	174	HDAC2; CCNA2; FOXM1; RBPJ; GTF2A2; TBL1X; CENPF; LMCD1; NRBF2; SP3; THAP4; RORA; ZNF217; MNAT1; BRD4; ZFP36L1; SUMO1; CHAF1B; CREM; ZNF672; SMARCA4; DNAJC2; SPEN; HMGB3; SAP30; RNF138; ZNF410; TRIM32; TFDP2; HCFC1; MYRF; GCFC2; ARRB1; PIAS1; SMARCA1; YEATS4; PSMC3IP; GTF2I; HSBP1; ZNF516; MYBL1; SMARCA5; HOXB2; E2F5; MYBL2; ZNF195; ZNF692; BAZ1A; PQBP1; EZH2; KLF10; BAZ1B; NFIL3; CNBP; NKRF; PRPF6; POLR3F; BCLAF1; TFAM; ATF5; ZMIZ2; PTTG1; INSM1; BANP; TEAD4; OSR2; C1QBP; WWTR1; WT1; CARM1; ZNF22; HIF1A; HMGA2; ARID1A; MKL2; ARNTL2; MAGED1; RARA; KAT6A; AR; ZBED1; IRF7; STAT4; PEX2; RYBP; MGA; ADNP; ZBTB18; ZNF146; CCNE1; MED21; PMS1; NONO; BACH1; HLTF; MLX; PPARG; TBPL1; CD3D; SIAH2; NR2F2; SIX3; TCF12; CBX6; PREB; AHR; HDAC4; MDM2; NFKB1; FOXF2; CREB1; NLK; ELF5; TAF5; TP53; BRD3; GATA3; TSC22D2; ASCL1; BIRC2; PARP1; TFAP2C; HOXA10; XBP1; INSR; ZNF586; TAF9B; EMX2; ELF3; PPRC1; ENY2; ESR1; HOXA11; TOX3; ING2; HIC2; SUB1; SUV39H1; SPDEF; ZNF331; PAX5; MITF; SOX2; KDM5D; CARHSP1; TXNIP; PIR; KAT6B; AGO2; NCOA4; IRX5; ZNF562; MNDA; TBX2; VDR; BRCA1; PUF60; ARID4B; ZEB1; POU2AF1; HOXB7; ATF1; PEG3; DMTF1; ERBB4; HHEX; TOX; IRF4; NR2F1; NUP62; FOXG1; MAFB; MSX1; IKZF1