Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76073	Ibrutinib	GSE92742	MCF10A	Human	24h	10uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	194	BTG1; SSBP2; CALCOCO1; MEN1; TP63; FOXN3; PHF1; RSF1; LPIN2; TBX2; ZNF354A; ZNF423; TSC22D3; HIVEP1; TDRD3; SREBF1; NCOA2; SMARCC2; ZFP64; RXRB; EHMT2; RELA; HINFP; ZNF688; PBX3; SOX13; KDM5B; TAF10; SMARCD3; MEIS1; EHMT1; MAZ; MNT; CBFA2T2; DDIT3; HMGA1; BAZ2A; PBRM1; FOXI1; INSM1; PHIP; SIRT2; MED16; ARNT; FOXC1; TTF2; BRD2; ADRB2; HDAC7; MED14; TOB1; SOX17; CREG1; SUPT5H; TFAP2A; RERE; TMF1; BRIP1; SIX2; MAML1; CTCF; ESRRA; KLF5; CEBPG; TRIM29; ZNF12; RFX7; TCF25; KLF11; SETD2; ZFHX3; KLF10; ARID1A; THRA; GON4L; SP2; PIAS4; CIC; PEX14; TCF3; CBX3; BCL11A; NFYA; HDAC9; AHR; CREBL2; MECOM; CHD9; NR5A2; PRMT2; FOXO3; JAK2; CNOT6; ZBTB48; ZNF224; PNRC1; ATF4; CUX2; DEAF1; ZMYND8; ARID4B; UBE2B; AES; LZTS1; PDLIM1; L3MBTL1; YEATS2; TSG101; ARID5B; PPARGC1A; RRN3; NFATC1; ZHX2; CDIP1; SOX15; TOPORS; BNC2; MED13; RB1; MED24; ZBTB16; THAP11; FLI1; SMARCA2; TRAK1; NCOA3; SHOX2; NPAS2; SOX11; PRKDC; ZNF232; FOSL2; NFKBIA; ZIC1; RBL2; KAT8; SNAI2; TCEA2; ZKSCAN1; BCL6; PFDN5; NR4A2; ZNF394; JUNB; ESRRG; SND1; CIZ1; HEY1; E2F2; ZNF43; BCL10; HIPK3; HOXB7; BRD4; ETV5; AEBP1; FOXF2; MEIS2; INSR; TDP2; FOXD1; TCFL5; ZFPM2; NRIP1; DAXX; ATF3; TERF1; ETS1; BCL11B; VGLL4; ZNF160; KLF2; AIP; CHD3; WNT4; STAT6; LITAF; LEF1; PCGF2; NR2F2; ZNF331; TGFB1; JUND; HTATIP2; FOXG1; CREB1; POU2AF1; ZNF91; KAT6B; MAFB; HOXB6; FOS; CEBPB; BASP1
Down-regulation	164	CCNA2; GTF2A2; LMCD1; HDAC2; ZNF248; EZH2; RAN; CENPF; SMARCE1; DRAP1; CHAF1B; CREB5; ENO1; KLF1; TFDP2; RBPJ; CEBPZ; HMGB2; DNMT3B; TBP; EGR1; HLF; SUB1; CCNC; FOSL1; DR1; ZNF3; NKX2-1; FOXM1; ITGB3BP; GCFC2; SMAD5; ILF2; PCGF3; NCOA4; MYF6; HMGXB4; FHL2; RBBP7; RBPMS; NFE2; PREB; ZNF654; BCLAF1; NEDD8; GABPB1; NR1H4; SPDEF; ATF6; EYA1; MTF2; PMS1; CHD8; RNF4; HMGB1; ZNF239; ZNF816; MED21; ESR1; ZNF337; MLXIP; SIM2; PTTG1; KAT6A; ETS2; KDM5D; ZNF410; USP16; SOX4; ETV1; IRF9; CARM1; ECD; RBM14; CBFB; TULP4; HIRA; RXRA; PIAS1; MAGED1; GTF3A; XRCC6; HOXA11; NFATC3; HLTF; RHOA; EGR3; DNAJC1; ZNF22; ZNF443; PEG3; TBX3; TLE4; SLC2A4RG; MYCBP; KLF6; ELF5; MYBL1; HHEX; MED6; PAWR; RBBP4; E2F6; CALR; SMAD1; CREB3L2; IRF8; APEX1; ZNF266; PAXBP1; SUV39H1; ZMYM2; ELK3; ZNF32; GATA3; CHD1; HOXA5; MED23; CCNE1; IRF5; CD3D; ZNF217; ZBED2; ARNTL2; MTA1; SMAD7; EGR2; MDM2; AGO2; PBX1; BRCA1; CNOT2; NFIB; ERBB2; YWHAB; XBP1; TCERG1; ZNF274; CBX6; TCF7; NFKB1; ID4; NUP62; E2F3; ZNF562; RUNX3; PITX1; HOXA10; TLE1; TP53; CHD7; SOX10; ZNF586; TRPS1; STAT1; MAF; HOXC6; NKX3-1; PAX8; SATB1; ERBB4; NR2F1; HIC2; SMAD3