Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76072	Linsitinib	GSE92742	MCF10A	Human	24h	0.4uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	107	HDAC9; INSM1; MAML1; CHD9; CSDE1; TTF2; SP2; HDAC6; ZNF195; SUPT3H; ZNF140; TULP3; ZBTB7A; NFYB; ZHX2; KLF9; ZNF354A; ZIC3; GATAD2A; ZKSCAN1; SMARCC2; FLI1; BAZ2B; CNOT6; TERF2; TSC22D3; SF1; PIAS4; ZNF232; MED13; CUX2; NR0B1; RBPJ; NFE2L3; ZBTB16; ZNF423; PRMT2; ETV5; NCOA3; SOX13; ZNF117; SSX1; NANOG; NRIP1; TCF25; PRKDC; AEBP1; RFX5; ETS1; RRN3; HBP1; ZNF432; ZMYND8; NAB2; MTA1; RYBP; BACH2; SND1; SUPT7L; ZMYM2; KAT2A; TRRAP; RNF6; CUX1; IFI16; ARID1A; SOX15; CLOCK; UBE2I; SREBF1; TRIP6; ASCL1; DMTF1; USP22; ECD; RFXANK; ZBED2; NCOA2; CTBP2; SALL2; CRK; HTATIP2; PSMD9; ZNF593; SPDEF; PFDN5; AFF1; FOXO1; MEIS2; PBX3; SUZ12; IRF9; INSR; FOSL1; HOXD1; FOSB; BCL11A; THAP11; STAT6; CITED2; ZNF91; TCERG1; RBPMS; TFAP2C; SNAI2; KAT6B; TRIM22
Down-regulation	120	HOXC10; DAXX; PRRX2; WWTR1; BRD3; ZNF226; CBX3; ZNF552; TRIM32; NR1D2; ZNF211; CALR; ENO1; DNMT3B; BCL3; BHLHE40; HLF; NFKB2; NR1H3; SIAH2; SKI; RARG; ZBTB43; HOXC6; IRX5; TBL1X; RXRA; PIAS2; PHOX2B; DBP; ZNF329; CAPN15; PITX1; SOX11; TFDP2; SMARCA4; SMAD6; ZNF331; TFCP2L1; TFEC; CCNA2; ELF3; NCOA4; CEBPA; ZSCAN31; TEAD3; EZH2; NR4A2; RNF14; KLF3; ZNF587; ZNF184; OSR2; KDM5D; SERTAD2; PSIP1; ZNF134; ZNF148; RBBP4; NFATC1; HMGB2; KLF10; NFE2; NR3C2; ZNF606; ELF5; BCLAF1; ID4; PEG3; CCNE1; IRF5; ZNF419; SATB1; PLAGL1; MBD2; MYCL; PHF20; BHLHE41; HMGN3; CENPB; ZBTB38; GATA3; RUVBL2; BATF; TBX3; ZNF264; XBP1; ZBTB18; CD3D; ABL1; BIRC2; IL16; ZNF443; RUNX3; GRHL2; HMGB3; AGO2; ZNF586; SUV39H1; REPIN1; GATA2; ZEB1; SMAD7; AHR; MNDA; IRF4; HOXB7; BASP1; TCFL5; ATF5; ARID4B; NKX3-1; WT1; CBX6; TCF4; TXNIP; TLE1; KLF4; IKZF1; TSC22D1