Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76071	Linsitinib	GSE92742	MCF10A	Human	24h	2uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	130	ZBTB16; HDAC9; HDAC6; FOXO4; TTF2; MEN1; TAF10; SSBP2; SOX13; TSC22D3; RERE; CREB3; PHF8; RELA; EGR1; FOXN3; ARL2BP; PRKDC; FOXI1; KAT8; FOSB; SOX9; TP63; ZNF669; SMARCA2; ERBB2; FLI1; SMARCC2; UBE2I; ZKSCAN1; PBXIP1; RSF1; ZNF394; ETV4; EHMT2; FOXA2; TAF6; MED1; EGR4; BHLHE41; TCEA2; INSM1; TRIM29; RB1; HBP1; NCOR2; HEY1; FOXO1; ATF7IP; ASH2L; FOXA1; TRIM22; ZHX2; SNAI2; BAZ2A; PNRC1; PCGF1; RRN3; TSG101; ARID1A; NCOA2; PBX1; ZNF140; PMF1; PBX3; MAFF; HTATIP2; CRYM; MED17; MLX; TRIP6; CREG1; CREBL2; SOX15; HOXB2; ERG; TRRAP; BTG1; IFI16; HDAC1; NR2E1; HOXD1; USP22; ARID4B; BAZ2B; ZNF232; DDIT3; ATF3; NR4A1; CLOCK; STAT6; SOX17; VPS72; HES1; LYL1; HOXB13; KAT2A; ZNF281; PSMD9; CIZ1; UBE2B; CUX1; MED24; HMGA1; RBPMS; HMBOX1; MED23; MAX; TERF1; KLF6; ZNF91; CRK; CITED2; ZMIZ1; JUNB; HLX; IRF9; RFXANK; RUNX1; TWIST1; JUND; ACTL6A; SUZ12; TBX3; AEBP1; JUP; SPEN; TFAP2C; EMX2; CEBPB
Down-regulation	167	GTF2A2; ZNF45; EYA1; SP3; NFKB2; SOHLH2; URI1; SOX11; ZNF184; ZNF226; HMGB2; ZNF711; ZNF180; ZNF112; ZNF227; DR1; DAXX; MXD3; ZNF571; PCGF3; NR1D2; PHF20; CCNA2; NEUROD1; ZNF248; ZNF23; ELF3; ERF; RNF4; CIC; SIAH2; BCL3; ZNF329; HOXC10; BANP; HOXA5; CAMTA1; CDYL; SERTAD2; ZKSCAN7; LIMD1; BACH1; ZNF148; RORA; ELK3; ENO1; BHLHE40; NFRKB; CRY1; HLTF; TRIM32; TCF20; ZFP30; RBBP7; GTF3A; NFE2L2; WWC1; PAX6; ZNF816; CARM1; ZNF253; CNBP; WWTR1; ZSCAN16; KAT2B; DACH1; CBX3; ATF5; NR3C2; DEK; ATF4; TBX21; EZH2; ETS1; ZNF415; IRF3; FOXF1; HSBP1; HLF; CENPF; ZBTB14; E2F2; DBP; ZNF264; CREM; ZBTB20; NFATC3; CHD7; ZMYND8; ZNF331; PRDM2; SOX10; TBL1X; ELF5; ZNF134; NCOA6; TAF5; SALL1; XBP1; SATB1; KDM5D; BCL6; NFIB; ZNF580; CENPB; RUVBL2; ZNF146; ZBTB38; NPM1; ZFPM2; MXD4; ZNF587; MYCN; PHOX2B; CREB3L1; TOB1; KLF10; ZNF273; ZNF467; GRHL2; NCOA1; ZNF562; CD3D; IKZF1; MNDA; TLE2; HNRNPD; SCAND1; SOX5; IRX5; PTTG1; ZNF124; THAP11; CHD3; HOXC4; YBX1; KAT6B; TGIF1; ID4; NKX2-2; ZNF22; PITX1; HOXC6; ZFHX4; VGLL4; ZNF267; ZNF586; TCF4; CCNE1; BASP1; CBX6; NR2F2; TOX; TRIM28; MAF; BIRC2; MAGED1; ZNF721; TCF7; SUV39H1; DMTF1; CREB1; ABL1; NUP62; TRPS1; TXNIP; ID1