Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76070	Linsitinib	GSE92742	MCF10A	Human	24h	10uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	166	HDAC6; HDAC9; TSC22D3; KLF9; ZNF665; ZBTB16; NCOR2; ZNF140; ATF2; SMARCC2; ZNF623; NAB2; DNMT1; ZNF83; SOX13; TERF2; ZKSCAN1; CHD8; ZIC3; ZHX2; ZNF611; RSF1; NCOA2; ZNF268; BCL10; ZIC1; ZNF93; ELF4; CDK2; POLR3C; CREBL2; ZNF135; HDAC5; FOXO4; ITGB3BP; HBP1; ZFPM2; ZNF12; MAFF; SOX17; ZNF394; RRN3; NCOA3; ZNF468; PBX2; ZNF91; TOX; MED14; ZNF667; ZNF224; MEIS2; INSM1; NFYB; PMF1; ZNF117; ZNF350; ZNF669; BLZF1; STAT6; BNC2; LITAF; CNOT6; TTF2; PBX3; SMARCD3; NRIP1; CHD9; ZNF532; KDM5B; MTF2; LIN28A; TBX21; ZNF551; SMAD2; BHLHE41; SUPT3H; AES; ETS1; REL; PRKDC; MED12; BRWD1; TCEA2; NFE2L1; TWIST1; THRA; WWP1; LEF1; ZNF304; ARID1A; ZSCAN18; TP63; RAD21; ZNF232; ZNF43; GATA6; TCF25; KAT5; ZNF302; RBFOX2; ZFX; LOXL2; TAF7; GATAD2A; SPDEF; IFI16; PDLIM1; ZNF423; CREG1; ZNF134; BCL11A; TCF12; MED24; CNOT3; HES1; HOXD1; PFDN5; RB1; FOSB; BACH2; TRIM22; TRIM16; JUND; MED13; SMAD7; ZNF85; NR4A1; ZNF586; TRIM29; NCOA1; RBL2; TCF21; CRK; CRYM; NR4A2; CDK9; FOXF2; PSMD9; RFXANK; ZNF281; TFCP2; ZNF587; PBX1; PAX5; ZNF160; INSR; PNRC1; TLE2; FOS; EHF; CBX7; MYRF; ASCL1; POU2AF1; MTA1; ABL1; KLF13; CEBPD; TCFL5; AEBP1; ZBTB38; ERBB4; EGR3; ATF3; SNAI2; SMAD3
Down-regulation	141	GTF2A2; RUVBL1; RORA; ENO1; GTF3A; ARNTL; HDAC2; CEBPZ; CASZ1; MXD1; POLR2A; TCF20; CCNA2; RXRA; CDYL; THAP4; MYOD1; CENPF; MYCBP; HSBP1; TBL1X; ASXL1; TRIM25; ARID4A; HOXA1; PPARG; HMGXB4; HIF1A; HMGB3; SCAND1; BCL11B; HOXC10; CALR; C1QBP; SPEN; BHLHE40; UBP1; HLTF; HOXC11; HHEX; PAX6; NR1H4; CBX3; PHF20; HLF; HOXA11; RUVBL2; SIAH2; LMCD1; NFRKB; LHX6; CNBP; ELF5; NFKB2; BRPF1; OSR2; URI1; NR2F2; SUB1; FOXE1; BANP; NR1H3; ZNF629; SATB2; SMARCA4; YBX1; SETD2; DLX2; MAGED1; TP53; ERG; HDAC3; BACH1; TEAD3; EZH2; MEOX2; TFDP1; KDM5D; NFAT5; SUV39H1; GRHL2; SIM2; HOXC6; HMGA2; SALL1; NFIB; ZNF148; AFF1; PRDM1; RREB1; VGLL4; CD3D; GFI1; ZNF443; ATF5; BRD3; THAP11; IKBKAP; PAXBP1; CHD1; BCLAF1; AR; KLF4; CCNE1; ATF4; PIR; ISL1; ETS2; AHR; KAT6B; TAF1D; CREB3L2; MYCL; MYB; ZMYM2; BIRC2; MAF; SOX11; DBP; XBP1; CREB1; ID4; IKZF1; SOX9; DMTF1; MAFB; TGIF1; ZNF266; EGR2; IRF7; CEBPA; TLE1; MNDA; IRX5; GATA3; TBX3; MSX1; RBPMS; GATA2; TXNIP; NUP62