Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76067	Mk-1775	GSE92742	MCF10A	Human	24h	2uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	211	SSBP2; PHF8; TAF10; NCOR1; ZNF783; HIVEP2; ZKSCAN1; MTF1; RFX7; ZNF665; EGR4; ID2; INSM1; NFKBIB; MAFF; LYL1; RAX; LITAF; CDX1; GTF2I; TLE4; RSF1; MTDH; SOX9; HDAC6; YBX2; FUBP1; TSC22D2; KDM5D; HAND1; SMARCA5; KLF9; SAFB2; SP2; RNF111; ZNF473; AFF4; ZNF282; SMAD6; MYRF; ZNF408; ZNF611; ST18; ZNF771; HDAC9; MAML1; HIPK2; PRKDC; ZNF671; CRTC1; ZNF93; AATF; NPAS2; TGIF2; SOX21; MBD4; BCL11A; ZNF667; CSDC2; EWSR1; MED24; EP400; ZNF84; MZF1; ERG; ZNF529; BAZ2A; TCF12; HIPK3; ZNF195; SATB2; ATF1; ZNF692; KAT8; RRN3; EHMT2; SCMH1; GATAD2A; ALX1; NR1I2; DDIT3; IKZF1; MLX; CHD7; TTF2; MNDA; MDM4; NFE2; ENO1; CREB3L1; MED1; ZKSCAN7; RYBP; TAF1; CHD9; CUX1; FOXD1; STAT4; NFATC1; SMARCA2; BATF; SNAI1; ZHX2; GATA4; ELF4; SPIB; TERF2; MSC; COPS5; SIX3; RBL2; ZNF721; ZNF574; ETV4; CBX5; RBBP5; TFEC; ZNF669; GATA6; TGS1; ZNF551; SSX1; EMX2; FHL2; UBE2I; ZNF140; FOXO3; WT1; ZNF573; NANOG; LEF1; TOX3; ZNF143; ZNF160; BRD7; EHF; YAF2; NFYC; GTF2IRD1; MED27; BACH2; NFIL3; ZNF652; TFAM; FOXA2; PSMD9; BAZ2B; ARID3B; TBL1XR1; BHLHE41; SOX11; MAGED1; PAX5; MTA1; ASH2L; TBP; ZNF124; ZNF587; NR2E1; SREBF1; HMBOX1; RAD21; BRD2; CRK; MED23; BCOR; ATF7IP; SMARCB1; FOXO1; THRA; RLF; CITED2; ZEB2; XBP1; E2F5; KLF13; USP22; KLF7; TFCP2; SMAD4; MYCN; ZNF91; FOSB; SIX2; CARHSP1; TGFB1; ZNF22; FOSL1; CCNC; ZNF83; YEATS2; BRD8; EDF1; PPRC1; ZBTB11; RHOA; SMAD7; ZBTB18; PFDN5; TAF1D; HIRA; POU2AF1; PEG3; IKBKAP; ACTL6A; TCERG1; IRF9; ZNF586; SNAI2; TP53; THAP11
Down-regulation	190	DRAP1; NR2F6; KAT2B; SP3; CERS4; CREM; FOXJ2; USP21; AHR; NOC2L; HMGXB4; TEAD4; ZBTB16; TULP3; CREG1; RXRG; TCF15; MEOX2; TP63; MAF; RXRA; HBP1; ZNF133; HOXD13; TFAP2C; NFIB; DNAJC2; RREB1; SUB1; RNF4; WWTR1; ZNF623; TRIM32; BCL6; RORA; ZFP36L1; ZNF512B; NFKB2; TEAD3; TSC22D3; TTF1; CTBP1; PCGF3; ZMIZ1; WWC1; CENPB; HIF3A; CBX3; FOXF2; NFE2L2; TFDP2; BHLHE40; CALR; RFC1; IRF6; THAP10; SOHLH2; MED7; CHD1; FOXM1; HIVEP1; RBPJ; ZBTB20; BATF3; RBL1; HLTF; HHEX; ZSCAN32; PBXIP1; ESRRA; HOXA5; CARM1; GRHL2; ARNTL; IRF7; SCAND1; TOX; PLAGL1; HDAC4; SP110; OVOL2; ZNF331; ARID5A; NKRF; RNF14; ZNF14; ZSCAN31; NR2F1; TRPS1; ZNF12; NR1H4; NR3C2; ZNF180; IRF3; DAXX; AFF1; CNOT2; XRCC6; FOXC1; SMARCA1; RBM39; NR4A2; ATN1; ZNF273; ZNF467; IFI16; IRX4; HLF; ID3; TLE2; TCF7L1; ZNF593; ZEB1; CBX7; NR2F2; TRAK1; PIR; AR; CREB1; PBX1; LOXL2; RARA; KLF4; RBBP7; ZFHX3; MXD4; ARNTL2; ZFX; SMAD1; ZNF43; PSIP1; ESRRG; FOXE1; MITF; RBBP8; ZNF32; TCF4; SOX10; ZFPM2; NR4A1; PDLIM1; MAFB; TAF5; KLF11; WWP1; ASCL1; DMTF1; PRDM2; SOX2; E2F2; BCL3; HDGF; BASP1; ESR1; DACH1; PHF20; MECOM; EGR2; ZMYND8; CDK9; SALL1; ZNF266; ZNF423; ZNF267; TGFB1I1; ID1; NPM1; HNRNPD; DLX2; GATA3; JUP; HES1; ATF4; WNT4; SATB1; SHOX2; ABL1; ELK3; RFX5; TBX3; BIRC2; KAT6B; CCNH; RBPMS; CBX6; DLX5; MTF2; GATA2; SUV39H1; MEIS2