Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76066	Mk-1775	GSE92742	MCF10A	Human	24h	10uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	126	TP63; HOXB1; TBX2; INSM1; TOB1; EYA1; ID2; HSF4; PTRF; FOXA1; SETD3; KDM5B; SUPT3H; MSL3; SSBP2; CREB3; TULP3; ZNF536; HIF3A; STAT4; APBB1; CSDC2; CREBZF; MTF1; TOPORS; PRDM4; CTBP2; RCOR1; CRYM; ZNF611; RELA; HOXB5; PRMT2; PSMC3; BARX1; TRIP6; FOXJ1; PAX6; ADRB2; ERBB2; PGR; SOX15; WWC1; ZNF329; ETS1; PSMC3IP; HOXB2; DMTF1; TCF21; HES1; EHF; TCF7L1; ESR1; ELF3; NR1H4; PDLIM1; FHL2; NR4A1; KLF6; BHLHE41; HOXB6; ZNF573; TLE1; GATA3; PSMD9; ITGB3BP; NHLH2; HOXD11; YAP1; NR4A2; MED17; ZNF426; KLF5; MXI1; CITED1; BIRC2; ZKSCAN1; BTAF1; LITAF; SNW1; EDF1; ZNF562; CARHSP1; PTTG1; UBE2B; SIX1; PITX1; MYBL1; CRK; ID1; SMARCA1; DACH1; TCFL5; RUNX3; SOX9; MEIS1; NR1H3; ELK3; BACH2; RUVBL2; TBL1XR1; TRIM16; ZNF423; ST18; ZNF131; WNT4; SMAD7; ZNF274; ZNF281; EYA2; ERBB4; SMAD3; FOSB; NFATC3; ZNF160; SNAI2; JUP; NR2F1; ZNF91; TBX3; PEG3; WT1; IKBKAP; NR2F2; FOS; CEBPB
Down-regulation	155	TFAP2A; SP3; ARID1A; BACH1; NCOR2; ORC2; BATF3; SERTAD2; ELF4; SUMO1; HCFC1; SAP30; NFIL3; GCFC2; TEAD4; NFIB; HMGB2; SP110; CSDE1; DR1; MYCBP; ZNF217; TSC22D3; RXRA; ETV6; SMARCA4; HR; KDM5D; RHOA; RERE; SATB2; NFE2L3; CAMTA1; RNF4; CNBP; CTBP1; NCOA4; BRD3; ZNF253; SMARCA5; HMG20A; SETDB1; CUX2; PLAGL2; PEX2; SPEN; CCNA2; THAP7; VDR; MED12; CREB5; ZFP64; ZNF267; VPS72; SMAD2; CAPN15; ZNF292; PHIP; HDAC4; ZNF189; CDYL; NKRF; NRBF2; PCGF3; PARP1; BCL6; ELK4; NR3C2; KAT6B; ZFP36L2; SP100; ZNF528; LMCD1; ZBED1; BLM; ATN1; PSIP1; FOSL2; DAXX; GTF3A; TFDP2; MNT; TBPL1; CNOT2; YEATS4; EGR2; ZNF124; SATB1; BCLAF1; CCNT1; C1D; TBL1X; SIAH2; CREB1; TOX; ZHX2; RNF138; PREB; ESRRG; HDGF; POU4F1; SMAD4; RBPMS; MAFB; HMGN3; GATA2; CNOT3; ING3; TAF9B; NFYC; BMI1; EGR3; HLF; CARM1; ZBTB20; SLC2A4RG; E2F6; MDM2; ARID4B; TDP2; STAT5A; ZNF43; VGLL4; TLE4; FLNA; ZFHX4; MEF2C; HOXA5; FOXC1; HEY1; PIR; ABL1; FOXO3; NKX2-2; CEBPA; SUB1; ZBTB18; ZNF512B; HOXD3; ZEB1; SALL1; TGFB1I1; TXNIP; NRIP1; MAF; NUP62; SUV39H1; CREB3L2; ZNF586; ZNF331; IKZF1; HOXC6; HHEX; MAGED1; BASP1