Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76045	Gsk-2126458	GSE92742	MCF10A	Human	24h	0.08uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	190	SSBP2; HDAC6; CALCOCO1; ZBTB16; INSM1; TSC22D3; KLF9; FOXN3; HDAC5; FOXO4; HBP1; BAZ2A; ZFP36L2; BTG1; PGR; PHF8; SMARCC2; PNRC1; HDAC9; ERG; HNF1A; RELA; TTF2; LMCD1; MLXIPL; PHF1; SMARCA2; SMAD2; ZKSCAN1; PSMC3; FOXO1; NCOR2; SOX17; CREB3; ZIC3; SNAI2; CRYM; SND1; PBXIP1; FOSB; MAZ; POLR3C; CREBL2; KDM5B; MAFF; STAT6; CHD9; LEF1; AEBP1; PBX3; ST18; SUPT3H; RYBP; PRKDC; CDX1; NRIP1; FLI1; SIRT2; NR2C1; PBRM1; SOX13; JUP; HEY1; TCF7L1; SETDB1; EWSR1; ZHX2; ZNF688; ATF2; RSF1; CREG1; TLE4; ZBED1; VGLL4; TRIP6; RERE; IKZF1; FOXA2; SALL2; TSG101; NCOA2; FOXA1; ARID5A; KLF6; SP100; RB1; RBL2; BAZ2B; ETS1; TERF2; PAX5; JUND; ZNF394; NPAS2; ZMYM2; LYL1; BACH2; PHIP; TWIST1; MED14; CDC5L; RBPMS; ARID1A; INSR; NCOA3; ZNF117; ZNF91; ZNF12; NR5A2; LITAF; SMARCB1; ZNF432; TULP3; ZNF516; RAD21; KLF4; KLF11; IRF9; TCF21; TFEB; BRF2; KAT8; MTA1; TFEC; IFI16; MED15; AES; OSR2; ARID4B; PSMD9; THRA; CTBP2; DPF2; ZNF423; PDLIM1; MLXIP; CRK; RLF; NFE2L1; ABL1; TRIM29; SPDEF; FOXD1; NKX3-1; KLF7; TAL1; UBE2B; NR4A1; EMX2; PBX1; ZNF721; SNW1; SHOX2; EHF; PFDN5; TLE1; BCOR; TERF1; TFAP2C; SOX9; DDIT3; CITED2; TRIM22; KLF13; ZIC1; KLF2; CEBPD; MYRF; VPS72; ATF1; RFXANK; ZNF160; TGFB1I1; TCF7; FOS; MEIS2; RUNX3; ACTL6A; ZEB1; TSC22D1; ATF3; HTATIP2; CREB1; FOXG1; PEG3; HOXB6; MSX1; CEBPB; POU2AF1; MAFB
Down-regulation	170	RUVBL1; HDAC2; GTF2A2; MYC; SOHLH2; CEBPZ; SP3; RNF4; MYCBP; ZNF45; TGIF2; ERF; CCNA2; NFKB2; PCGF3; DR1; CHAF1B; TFDP1; TRIM32; ORC2; CENPF; TEAD1; ABT1; GTF2I; CDYL; BHLHE40; IRX5; DNMT3B; ZNF226; THAP10; ZNF227; GCFC2; HLTF; PMS1; ZSCAN32; E2F2; ZNF211; NAB1; SUMO1; ELF3; BATF3; TRIM25; ZXDC; SMARCA5; POLR2A; ZNF180; ZNF552; HOXA5; TFDP2; RBBP4; RBL1; ZNF200; DAXX; RFC1; NCOA6; BCLAF1; HNRNPD; ZNF576; ZNF711; SUB1; NR2F2; YWHAB; ENO1; PITX2; HOXC10; SATB1; MYCN; FOXC1; SERTAD2; ZNF329; ZNF8; ZBTB14; SCAND1; ZNF148; CCNE1; GTF3A; ZNF443; ZNF239; SMAD6; SOX11; HSBP1; ZNF551; URI1; ZNF134; HES1; BCL3; ATF5; ZNF468; ZNF7; MXD4; MEOX2; NFIB; BRD3; USP16; BANP; CTNNB1; C1QBP; CCNC; ELK3; ZNF692; PAXBP1; ZNF266; ZNF324; KAT6B; ZNF419; MDM2; MYCL; PREB; MGA; TP53; BBX; SFPQ; BIRC2; ZNF587; ZNF562; PHF20; EZH2; KMT5A; WWC1; PHOX2B; PITX1; ZNF43; HIRA; ZNF586; DMTF1; EGR2; E2F5; HOXB2; NFATC3; SATB2; TBL1X; ZNF217; AGO2; CBX6; ZNF331; ZNF512B; ARNTL2; KLF10; TRIM28; NFKB1; ZNF593; ZNF124; ZNF146; NKX2-2; PURA; KDM5A; RUVBL2; PIR; E2F6; ZNF131; ZNF580; TLE2; GATA3; CEBPA; ING2; SMARCA1; SIAH2; HOXC6; PTTG1; HOXB7; TGIF1; WT1; TOX; ZBTB18; NUP62; SUV39H1; IRF4; SMAD3; NR2F1; ID1