Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76036	Gsk-1059615	GSE92742	MCF10A	Human	24h	10uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	274	PPARD; RSF1; POLR2A; ZNF117; E2F2; ETV1; LEF1; PROX1; DACH1; CHD9; MKL2; HEY1; PCGF3; TSC22D3; ZMIZ2; MDM4; CBL; MXD3; ZNF506; TWIST1; CREBZF; CDYL; POLR3C; HNF1A; TOX4; HDAC9; TCF7; ZNF141; SNAPC4; PAX5; PHIP; BTG1; HOXA1; ZNF93; SPDEF; RNF141; TULP2; TRIM24; ETV6; NKRF; BCL10; NCOA2; BCL6; BACH2; DDX17; CREB3; FUBP1; RXRB; PRMT2; CALCOCO1; SAP130; MED20; CDX1; SMARCC2; FOXJ2; TULP4; INSM1; SHOX2; SP3; PKNOX1; CREB3L2; PBRM1; AATF; PATZ1; RELA; LZTS1; PRDM10; ZNF224; SETD2; FOXE1; ZNF76; RARB; GLI3; SOX21; MAFB; HOXD1; SPIB; SATB2; TFEB; ZNF589; DLX5; ZSCAN16; ID4; TCF25; PIAS3; YBX2; ETV5; PAX1; MEN1; DR1; CDC5L; VPS72; HMBOX1; SND1; HMGA1; MYCL; HCFC1; IKZF1; ZNF623; PRRX1; VGLL1; TRIM29; KLF13; CHD2; MLXIP; MTDH; ZNF652; MDM2; MSX1; UIMC1; TTF2; TP63; SNIP1; KLF3; NKX3-2; GBX2; TLE1; CTCF; RERE; STAT2; TRIM25; KMT2D; ARNTL; HMGN3; SMARCA1; ZNF24; MAML1; EWSR1; BRD2; ETS1; DEK; ZNF467; TMF1; OLIG2; ESR1; TCF4; ZNF430; ARL2BP; GATA1; MECP2; ZMYM2; TGFB1I1; XBP1; MED14; CITED1; PPARG; PAWR; GATAD2A; SSX1; TCFL5; ZNF212; CUX1; SNAI2; FOXG1; ISL1; BACH1; FOXO1; RNF111; FOXC1; ZNF528; MTA1; SERTAD2; VGLL4; TOPORS; ACTL6A; BAZ2A; CBFA2T2; RNF4; ASCL1; MNT; ZFPM2; TRIM22; SP140; SOX2; PAX8; ZHX2; NHLH1; AEBP1; CTNNB1; WIZ; PHF20; MEIS2; SFPQ; ELF4; ECD; HDAC4; TLE4; ZNF721; CDK9; FOXA1; ZNF253; RELB; SOX4; NAB1; RRN3; MKL1; ZNF200; SAFB; JUP; PRDM12; CBX6; NAB2; RFX5; ZNF444; ZFHX4; NFAT5; ZNF512B; RARG; MED4; NFKB2; TCF12; SPEN; SMARCE1; PRDM2; LIN28A; BRWD1; DLX2; KLF2; POU2F1; PSMD9; OSR2; ZNF217; PEG3; CBX7; RB1; TERF1; EYA2; TRPS1; IL16; TAF1D; SOX10; NFE2L3; ELK3; HOXC4; MEF2A; CLOCK; SLC2A4RG; HOXB6; ARID3A; BAZ1A; DAXX; PBX3; ZNF160; EGR3; WNT4; LOXL2; EN1; LYL1; ZBED2; TBX3; VDR; NR2F1; POU2AF1; HNRNPD; BMI1; RBPMS; GABPB1; NFATC3; CRK; BCL11A; PARP1; ZNF281; KAT6B; CCNH; MYBL1; HIC2; IRF9; TFAP2C; HOXC6; HHEX; IRF4; PSIP1; ERBB4; TXNIP
Down-regulation	263	RUVBL1; HDAC2; TFDP1; CCNA2; ZNF133; ENO1; THAP4; ZNF32; CTBP1; YWHAB; ZNF112; GTF2A2; ZNF239; SMAD6; MYC; CEBPZ; KDM5D; IRF1; ZNF274; TEAD4; ZNF473; RUVBL2; THAP10; NR4A3; SUB1; MED21; HMGB2; NFE2L1; SSBP2; FHL2; GCFC2; MNAT1; URI1; ZNF23; WDR77; NFIC; ERF; ZNF227; ZNF576; RXRA; PIR; ATN1; TAF7; RCOR1; CDK8; SAP30; PGR; IRF2; MXI1; CNBP; PITX1; GTF3A; RNF138; WWC1; SUMO1; POLR3F; TCF21; ZNF331; DDX5; TFAM; SAP18; ID3; CENPB; THAP7; CIC; ZSCAN5A; CBX2; PPARGC1A; MED12; MED24; ZNF426; MED16; ZBTB7A; C1QBP; AES; TFDP2; ZNF787; CIZ1; SUPT5H; TRIP6; PSMC3IP; CREBL2; ZFP36L1; PLAGL1; CNOT3; MED13; HOXD10; USP22; ZNF571; NCOA4; TAF5; REXO4; TFE3; DNAJC2; ADNP; SIAH2; TULP3; ZNF175; ZNF667; PTRF; ZBTB38; BCL3; ARHGAP35; MYBL2; CCDC59; HMGB3; MTF2; SUZ12; ZNF177; UBE2L3; SP110; MED17; RBL1; SMAD4; ZSCAN31; ZNF350; IKBKAP; NR1H2; SUPT4H1; CAMTA1; NELFB; FOXL2; RORA; BHLHE40; EMX2; PRDM4; ZNF574; ZNF232; RREB1; ING2; THAP1; ZNF551; ZNF155; HSF2; ITGB3BP; SOX9; CREB1; NPAS2; ZFP69B; PIAS2; ZBTB11; BRD4; NCOR1; MMS19; ATF5; E2F5; ZNF337; HOXA7; ADNP2; ZNF134; ZNF91; MGA; HES1; THAP11; MEF2D; ZNF468; PIAS1; HDAC3; ZNF136; EP300; ZNF544; RBBP5; PTTG1; FOSL2; RNF14; ZSCAN18; UBE2B; SMAD7; ZIC1; MED15; CARM1; SOX12; ZNF165; MYCBP; ZNF148; CCNT1; RBM39; ZMYND11; IRF3; ZNF562; NR1H3; CCNC; ZNF83; NR1I2; PSPC1; ZNF211; ZNF264; HSBP1; MED27; CNOT2; LITAF; ATF1; SSBP3; SUPT7L; BRD8; ZNF419; NR4A2; BIRC2; JARID2; INSR; PPP1R13L; CCNE1; WT1; PQBP1; SOX15; RBM14; BASP1; ZNF606; ZNF394; HOXB13; SMAD3; TAL1; TBP; NFIB; PSMC3; TBX2; NRIP1; PPRC1; PREB; ZNF593; NFYC; ZNF131; FOS; EDF1; TGFB1; ZNF587; ZNF586; CITED2; GATA6; MAX; ID1; TRIM28; TP53; HIPK1; ZNF304; JUNB; ZMIZ1; ABL1; HIRA; ID2; TGIF1; E2F6; KAT2A; BHLHE41; CEBPB; PURA; STAT6; TSC22D2; PUF60; ETS2; STAT1; DMTF1; SUV39H1; ERBB2; MECOM; ATF3; ARID4B; NUP62; KLF6; BRCA1; SATB1; GATA3; PBX1