Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76030	Doramapimod	GSE92742	MCF10A	Human	24h	0.4uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	130	NFATC4; TTF2; RFX7; HDAC9; CHD9; ZFP36L2; BRIP1; ID3; GLI2; SMARCC2; MED1; ZNF345; INSM1; TAF9; HEY1; CUX2; SOX9; RAD21; BRCA2; NR2C2; CBFA2T3; MBD2; DACH1; PRMT2; MDM4; BNC1; NPAS2; MED13; NEUROD1; BAZ2A; ZNF12; TFAM; TADA3; SUPT3H; NHLH2; CSDE1; POU3F2; RNF111; ETS1; FOXN2; HES1; SPIB; TCF12; VEZF1; YEATS4; FOXA2; HIF1A; ZNF589; CAPN15; UBE2I; SNAI2; ZFP69B; ETV1; PBX3; ZNF22; ELF4; NRIP1; VPS72; NAB2; ID1; ZNF232; ECD; RNF138; FUBP1; MTDH; ZNF34; MED17; ILF2; MEOX2; RB1; PAX6; TP63; SPDEF; SIX3; PSMD9; YEATS2; SETDB1; CCDC59; MMS19; THRA; CCNT1; ASCL1; ZNF574; BCL10; HMGN3; WWTR1; ACTL6A; CCNC; ZNF532; MTF2; ZNF33B; IFI16; KAT8; MEIS2; PCGF1; CERS6; PDLIM1; ATF1; ZEB1; PREB; PRKDC; NR2C1; JUNB; PAX5; EZH2; STAT6; ATF7IP; HIRA; HOXA5; SUZ12; CTBP2; PNRC1; SFPQ; RFXANK; CCNH; ZNF124; ST18; KLF13; ETS2; PBX1; ELK3; CRK; SOX11; MYRF; ZBED2; PFDN5; TGFB1I1; SMAD7; TRIM22; CEBPB
Down-regulation	147	TRIM16; RORA; CALCOCO1; RNF141; ZNF226; DNMT3B; KAT7; TRIM32; TFAP2A; ESR1; LIMD1; LPIN2; MAF; ENO1; SP3; RXRA; CASZ1; TFE3; SIAH2; BHLHE40; SMARCD3; TEAD3; ZSCAN31; ZNF23; ZNF3; NFIC; ZNF44; CDYL; FOXJ1; CARHSP1; KDM2A; IRF7; NFE2L2; ZNF45; PCGF3; AR; KAT2B; ZNF552; TULP4; STAT3; E2F2; NR1D2; DEAF1; FOXC1; BRD3; NANOG; DAXX; NR1H2; HOXC10; ZNF665; TGIF1; PIR; ZNF329; ZNF654; KLF2; XBP1; MAFG; HDAC4; HIVEP2; MXI1; NFKB2; HOXC6; HOXB2; PSPC1; LIN28A; BHLHE41; ZMIZ2; CTBP1; HLTF; CITED2; GRHL2; HIPK3; ZNF264; IRX5; URI1; HMGA2; PEG3; SPEN; KLF4; AFF1; RBM14; ZNF274; ZNF419; ELF3; TBL1X; BCL3; SMAD1; MNDA; CREB3L1; HLF; FOSL2; PBXIP1; MAFB; CBX7; KDM5D; BIRC2; MGA; SCAND1; NR3C2; ID2; NFE2; NPM1; SAP18; TCF4; VDR; FOXF2; BASP1; MYB; PHF20; NFATC3; CCNE1; ZNF331; TFAP2C; ZNF587; WT1; REL; ZNF160; TCFL5; YWHAB; WNT4; CEBPA; MEIS1; AHR; JUND; ZNF131; NKX2-2; SALL1; ING2; ZNF580; TCF7; HOXA10; GATA3; LITAF; HHEX; NFIB; ZNF512B; FOSL1; IKZF1; GATA6; HTATIP2; SOX10; GATA2; NUP62; HIC2; SUV39H1; TXNIP; SMAD3