Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76029	Doramapimod	GSE92742	MCF10A	Human	24h	2uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	130	ID3; SMARCA5; KLF9; ASCL1; MAML1; HIPK2; SP3; ERF; ID1; ILF2; FOXA2; RNF6; MBD2; ETS2; TMF1; ZNF226; NCOR2; ATF2; MLX; VEZF1; PGR; MED17; CRYM; ZHX3; MED1; CREB3; TRIP6; CNOT6; RYBP; KAT5; ZKSCAN1; MKL2; SMAD5; HEY1; HES1; MED24; DACH1; CHD8; CCDC59; SUPT4H1; SUPT3H; ZNF136; LEF1; BRD7; PFDN5; MYRF; TCF12; HMGB1; KLF2; TCF21; BCL6; ZNF516; TERF2; MLXIPL; UBE3A; SSRP1; CERS6; ZNF551; ZNF652; BAZ1B; PMF1; NRIP1; MED6; PDLIM1; RRN3; IRF2; MAFF; ZNF587; TOX4; ZNF146; JUNB; CUX1; EZH2; INSM1; NAB1; PROX1; CBX5; ETV1; MED23; TSC22D1; RFX5; RB1; SOX17; PTTG1; NR4A1; CTNNB1; EMX2; PSMD9; ZNF91; LITAF; NPM1; ZNF586; CUX2; TP53; SMAD4; ST18; BCL11A; ZNF83; KLF6; PCGF2; HLX; SOX9; CRK; HMGA1; SAP18; ACTL6A; ZNF264; CLOCK; CCNH; MEIS2; FOXO1; FOXG1; CBFB; SUB1; MSX1; EYA2; STAT6; SUZ12; HIRA; ASH2L; ATF1; ID4; KLF13; TCERG1; HMGB3; SMAD7; CREB3L2; CREB1; MECOM; ATF3
Down-regulation	124	DLX4; DNMT3B; SOHLH2; TBL1X; TAF1A; HOXC10; TFDP2; KDM4C; SOX11; RREB1; TEAD4; PARP1; OSR2; ZNF7; GTF2I; BCL11B; MXI1; MAF; CAMTA1; ZNF623; CD3D; MYBL1; CALCOCO1; KLF11; TLE2; ZEB2; HOXC6; GRHL2; CITED2; CALR; PTRF; TGIF2; GCFC2; FOXE1; WT1; RORA; DAXX; KLF4; APBB1; ZMYND8; ZNF536; ZNF711; ZZZ3; PHF20; CSDE1; TERF1; ZNF239; ZXDC; KLF3; NFKB2; IRF1; RUNX3; NFATC3; TEAD3; SP140; IRX5; MEOX2; EDF1; NKRF; MTDH; ZNF654; BHLHE41; SMARCA4; HSF1; ZNF148; NHLH2; JARID2; NR4A2; FOXF2; MNT; JUND; ZNF175; MGA; ARNTL2; NKX2-2; SPEN; WWTR1; SMAD1; BRD3; HOXA5; TRAK1; GFI1; MAFB; IKBKAP; NR1H3; ZSCAN31; PRDM2; HMGB2; PSIP1; MAFG; GATA3; ZFPM2; INSR; TFAP2C; HOXC4; TRPS1; ZNF580; KLF10; SOX2; HOXB7; SOX10; AFF1; SATB1; DLX2; AHR; GATA6; IKZF1; TBX2; FOXC1; ATF5; ID2; DMTF1; ESR1; PITX1; TXNIP; SIX1; PEG3; CBX6; TLE1; ZNF331; HOXB6; ERBB4; BASP1; KAT6B