Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76028	Doramapimod	GSE92742	MCF10A	Human	24h	10uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	121	SMAD6; CERS4; CREM; BRCA2; TERF2; ZIC1; TCF7L2; BTG1; ZNF423; HEY1; TTF2; HIVEP1; ZHX2; FHL5; CREB5; ZBED1; FOXC1; PITX2; NR4A3; FOXA2; E2F8; GATAD2A; FOXJ3; EPAS1; UBE2L3; TAF6; TP63; ZBED4; HEY2; PEX14; TCF7L1; BHLHE41; SOX11; MED21; CAMTA1; ID4; ARID5B; FOXF2; POU4F1; FOXF1; CSDE1; ZNF394; INSM1; ZNF652; TULP4; PDLIM1; SOX13; CBFA2T3; ZZZ3; TRIM29; SMAD2; SOX9; CDYL; ZNF430; TRIP6; SPDEF; TSG101; SIX3; ZKSCAN1; KLF5; ZNF426; THRA; TCFL5; NKX2-1; ARNTL2; XRCC6; BACH2; SNAI2; PFDN5; WWTR1; HMGA1; KLF2; MYB; BCL11A; NFE2L3; CERS6; PBX1; PSMC3; RBBP8; MNDA; CLOCK; ETS2; TFAP2C; ABL1; DACH1; DLX2; SOX4; NR0B1; OSR2; TBX3; PPRC1; NR4A1; MED13; ZBED2; INSR; REL; SUZ12; RBPMS; NCOA1; JUNB; CREB3L2; REPIN1; EGR3; ETV5; CRK; FOXO1; GRHL2; BRCA1; PSMD9; SMAD7; NR2F1; ELF5; PAWR; ASCL1; NR1H2; ACTL6A; POU2AF1; THAP11; KAT6B; ERBB4; ID1
Down-regulation	146	TRIB3; ZNF226; ZNF217; HOXB2; SOHLH2; HCFC2; HDAC9; CBX3; ZNF552; NFIC; VEZF1; ZBTB25; ELF3; ZNF337; ARNTL; NFRKB; ZBTB40; ZNF654; ZNF23; ZNF576; ZNF222; MNT; HOXA1; ZNF45; POU5F1B; PCGF3; BAZ1A; KLF10; KLF7; ZNF324; FOXO4; MAFG; MYCBP; IRF3; ZBTB1; ZNF671; ZNF211; ZNF227; LPIN2; TOB1; SP100; SETDB1; ZNF711; CBFA2T2; ZNF701; PSIP1; LEF1; ZMYND8; CREBZF; ZFP36L2; NRBF2; ZNF446; ZNF83; LIMD1; ZNF3; MLXIP; IRF8; IRF1; ELK3; ZNF835; KMT2A; PIAS2; BACH1; ZNF587; MEOX2; YWHAB; TRAK1; NFIL3; ST18; ZBTB14; SATB1; ZNF266; HOXD11; FUBP1; JAK2; HOXB7; ID3; RORA; YBX1; MAZ; ZNF134; FOS; ZSCAN9; CHD4; NONO; IRF5; CHD1; ZNF302; HHEX; UBTF; ELF4; KAT2A; KAT6A; IKBKAP; FLNA; ZNF419; KDM5B; KLF6; MEIS1; ZBTB38; BRF2; NFE2; WT1; ATF5; DBP; BTAF1; AHR; EYA2; NFIB; HOXC4; ZNF562; BIRC2; EGR2; FOXO3; EMX2; RBM39; TP53; SIX2; FOXD1; MITF; XBP1; MTA1; RFX5; ZNF580; MEF2C; TWIST1; ZNF586; TAF1D; CEBPA; HMGB3; GATA3; CBX6; CEBPD; IKZF1; NUP62; CREB1; NR2F2; DMTF1; MAGED1; MECOM; TGFB1; HOXC6; SMAD3; ZNF131; TLE1; TXNIP