Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76027	Ldn-193189	GSE92742	MCF10A	Human	24h	0.08uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	176	TTF2; HSF2; HDAC6; PHF8; YEATS4; PHF2; PCBD1; HDAC9; TAF10; ERG; ZNF165; MNAT1; ZNF432; SMAD2; ZNF226; EED; CRY1; YAF2; CCDC59; PIAS2; TFAM; DMRT1; RELA; TRAF6; MED1; ORC2; RRN3; PATZ1; ATF1; GFI1B; EGR1; SAP30; DDX5; UIMC1; MED27; PRKDC; MLXIPL; NRBF2; SOX15; TBP; TMF1; HIVEP2; USP22; ELK1; UBE3A; FOXA1; RFX7; CREB5; ERBB2; DRAP1; IKZF5; MED6; MLX; WDR77; TFEC; ZSCAN5A; ZSCAN12; HTATIP2; AATF; TRIP6; ELF1; BAZ1A; DPF2; RBBP5; ZNF468; ZNF410; PMF1; CREB3; NR2E1; ZNF143; ETV1; EGR4; MYNN; RUVBL2; FOXO1; KAT5; TSC22D2; PCGF2; HOXA5; HMGA1; ZMIZ2; VEZF1; MED21; SMARCA2; BRF2; EHF; THAP1; STAT6; TSC22D3; SP2; LYL1; ZNF140; FOSB; FOXN2; ARID4B; RNF10; PSMD9; SETD2; FOSL1; MAFF; BAZ1B; PTTG1; SAFB2; SNW1; PPARG; ZNF302; KAT8; ZNF267; ZBED4; NEDD8; BAZ2B; ABL1; RYBP; RNF6; C1D; ZBTB11; CRYM; ZNF24; ELF4; RBBP4; GABPB1; UBE2I; SOX9; ASH2L; ACTL6A; BCL10; CCNC; TCERG1; CRK; ECD; BRD8; CBFB; CTNNB1; CNOT2; MYCBP; RFXANK; ZNF593; MEIS1; HDAC1; LITAF; EZH2; MED23; DDIT3; HEY1; RUNX1; RBM14; PBX1; CHD7; NFIB; SUB1; HES1; USF2; PPRC1; SUZ12; ZNF532; CCNH; ETS2; VGLL4; YWHAB; SOX17; TSC22D1; PIR; IKBKAP; SPDEF; GATA3; VDR; SAP18; FOXO3; SCAND1; TCEB2; MTF2; NKX3-1; CTBP2; PSIP1; TOX; AEBP1
Down-regulation	161	HMG20B; NFKB2; NFE2L2; PCGF3; ZXDC; PHIP; ZNF611; DLX4; NR4A2; MNDA; IRF7; CREB3L2; SMARCA1; SOHLH2; CALCOCO1; JUN; EYA1; DAXX; TRIM25; ZNF331; NFIC; KAT2B; ZNF74; FOXE1; TCF7L1; ZNF248; NHLH1; FOXD1; PRRX2; TULP4; RARG; ZNF43; ZNF711; TBL1X; ZNF117; E2F2; BARX1; OSR2; NANOG; HLF; ZNF329; ZNF133; LIN28A; MYCN; SUMO1; ZBTB17; RBPJ; PKNOX1; ZNF665; ZFP36L1; EZH1; POU4F1; SMAD6; MXD4; ZNF93; JAK2; ZNF512B; BACH1; TFDP2; HIC2; IRF5; ZNF264; EP300; TCF3; TEAD3; ZNF430; ID4; ZNF44; DLX5; ZNF180; RREB1; ZNF14; DBP; NEUROD1; CDIP1; TCF7L2; URI1; BANP; ZBTB48; CBX4; CBFA2T2; ZNF268; WT1; ZNF148; ZBTB20; HMGA2; NR3C2; MAF; KLF3; ZNF536; PITX2; TCF4; NFATC3; MXI1; ARID5B; SALL1; KLF11; HOXB2; ZNF253; RBFOX2; HMGB1; GTF3A; BHLHE40; PIAS1; ZIC1; CUX2; HOXD3; ZNF160; PRDM2; CBX7; TGIF1; ZNF217; FLNA; PRRX1; SOX11; ERBB4; BCL3; FOXF2; FOSL2; MYBL1; REL; ZEB1; MGA; SOX2; DACH1; ESR1; ZNF586; DLX2; EGR2; ARID3A; CARHSP1; MYCL; FOXF1; NCOA1; TGFB1I1; PEG3; CREB1; IRF8; TBX2; ATF5; TCF7; YAP1; ZNF266; IRF4; BCL11A; GATA2; HIRA; GATA6; IKZF1; TBX3; TRPS1; KLF4; NR2F2; TXNIP; ID1; SOX10; DMTF1; ATF3; POU2AF1; THAP11; TOX3