Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76024	Ldn-193189	GSE92742	MCF10A	Human	24h	10uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	170	HSF2; PHF8; HDAC6; TAF10; TTF2; ZNF226; EED; TMF1; SAP30; ORC2; BRIP1; MED1; SMAD2; RFX7; MNAT1; ZNF143; HDAC9; GABPA; YEATS4; POU3F2; TBP; BAZ1A; USP22; PCBD1; ELK1; CREB5; WDHD1; ETV1; EGR1; MLX; MLXIPL; NFKBIB; NR1I2; HIVEP2; ADRB2; NCOR2; ATF1; YAF2; IKZF5; AATF; ERG; TSC22D2; CRY1; BMI1; PIAS2; MTDH; MBD2; MAFF; SMARCA2; RRN3; TAF9; SOX15; ERBB2; GABPB1; PSMC3IP; CREB3; CCDC59; TEAD1; HTATIP2; POLR3F; MED6; TRIP6; NPAS2; BLZF1; DDX5; ASH2L; RNF111; FOSL1; TFAM; GATA4; RBBP5; CREBZF; TAF1D; BAZ2B; PATZ1; C1D; ZNF432; NR2E1; TAF4; LEF1; TSC22D1; UIMC1; PMF1; DDIT3; SP2; PSMD9; ZNF384; ZNF302; MED17; NEDD8; SAFB2; ZNF516; SATB2; ID3; FOXO1; TOB1; HOXA10; HMGA1; USF2; TERF2; MED27; DPF2; SAP18; CTR9; PRKDC; MED4; PTTG1; CRK; ELF1; ARID4B; RBM14; KAT5; BRF2; RUVBL2; PAXBP1; ING3; TCERG1; YAP1; CBFB; STAT6; ETS2; CREG1; KMT2B; UBE2I; ZNF652; EMX2; KDM5D; BRD8; KAT2A; LITAF; MED23; ACTL6A; MYCBP; ZBTB11; OLIG2; TRIM16; EZH2; CCNC; KAT8; NFE2L1; KLF6; ZKSCAN1; RNF6; ZNF83; TBL1XR1; MSX1; PIR; SOX9; PCGF2; SUZ12; PNRC1; ZNF532; SNW1; RFXANK; EGR3; IKBKAP; SCAND1; ATF5; PPRC1; ASCL1; TCFL5; BRCA1; FLNA; ABL1; TRIM29; RFX5; RBPMS; SUV39H1; CEBPB; FOXG1
Down-regulation	178	CALCOCO1; ARNT2; NFKB2; DLX4; SP3; ZNF711; ZFP36L1; ZXDC; NFE2L2; GATA1; RXRG; BARX1; ZNF331; USP21; KAT2B; RBPJ; PRDM14; LIN28A; DAXX; TBX21; TCF7L1; SMARCA1; RARG; GTF2I; PCGF3; TEAD3; PRDM2; TEAD4; ID4; NR4A2; KLF3; LHX3; SOHLH2; E2F2; FOXF2; ZNF117; SSBP3; ZNF665; PARP1; OSR2; TBL1X; HOXB2; KDM4C; CBFA2T3; NHLH1; THRB; TCF4; ZNF253; IRF6; ZFPM2; ZZZ3; MAF; FOXE1; LMCD1; TFDP2; NFATC1; ZNF74; GRHL2; DLX5; EYA1; NEUROD1; ZNF816; PRDM12; ERBB4; EPAS1; RORA; SERTAD2; KDM5C; MYBL1; IRF5; NFATC3; ESR1; AR; NANOG; ZNF44; ZNF329; CREM; WT1; HIC2; RARA; SOX5; BNC2; TRPS1; ZNF654; TCEA1; IRF9; PHIP; SOX2; PAX6; TFAP2A; SREBF2; KLF1; ZNF266; RING1; CREB3L1; SP140; DBP; RBFOX2; FOS; HMGA2; ZNF43; IRF7; TXNIP; ZNF415; ATF4; PEG3; TGFB1I1; ZNF180; HMGN3; MNDA; ARID5B; FOXC1; IKZF1; CBX4; ZNF512B; WNT4; URI1; AES; ZNF467; PBXIP1; HOXA5; CBX7; MYCN; HHEX; TLE2; HMGB2; KLF10; ZNF148; TSC22D3; CBX6; CREB3L2; ZNF264; ZNF124; DMTF1; ZNF586; ZNF217; NFE2L3; BRD4; SATB1; ZNF423; MYCL; FOXF1; ELF3; SOX10; HLF; REL; ZSCAN18; NCOA2; PAX5; SIAH2; HSF1; CREB1; BHLHE40; ZNF580; GATA6; AHR; TERF1; TOX; ZIC1; NKX2-2; KLF4; IL16; NCOA1; SALL1; TFAP2C; TBX3; PAWR; ZNF562; MEIS2; ID2; IRF4; GATA2; NR1H2; HOXC6; EGR2; PSIP1; KAT6B; GATA3