Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76023	Celastrol	GSE92742	MCF10A	Human	24h	0.08uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	173	TTF2; RFX7; HSF2; HDAC6; FOXI1; PHF8; MLLT10; ZNF263; TAF9; USP22; ZNF432; CREBZF; TAF10; ZNF10; PCBD1; MLXIPL; TRAF6; ELK1; PRKDC; INSM1; BRIP1; MED17; WDR77; STAT6; SPIB; MED1; RRN3; BAZ1A; CHD9; EWSR1; YEATS4; CCDC59; ZBED4; BACH2; AATF; VGLL4; PCGF2; MED4; MEN1; UBE2I; MTDH; SIX2; VEZF1; HOXA5; RSF1; MDM4; MED27; ETV1; ARID4B; MED24; THRAP3; C1D; ATF1; ZNF143; ASCL1; ZNF468; ACTL6A; RNF111; KAT8; POLR3F; MED23; BAZ2A; HDAC9; ZFX; RFX5; BRF2; ETS2; ETV4; TSC22D2; ZNF84; FOXO1; TBP; HMGA1; ZNF516; ZNF195; SETD2; HIVEP2; NKRF; PAX5; RNF6; BAZ2B; TSC22D1; TAF4; FOXN2; ZNF302; HIF1A; ILF2; CEBPD; MED6; BPTF; YAF2; CRY1; CTBP2; MMS19; HDAC1; ZNF140; FOXO3; MKL2; KAT2A; TFAM; ZNF83; XRCC6; RUVBL2; TOB1; PSMD9; PMF1; TCERG1; FOXA1; BTG1; RBM14; KMT2B; HTATIP2; ZBTB11; ELK3; KLF7; SUZ12; SMARCA2; RFXANK; SOX15; MAZ; ID3; CRK; VDR; TP63; NEDD8; CERS6; SMAD1; IKBKAP; GABPB1; RNF138; BTAF1; TBL1XR1; ATF7IP; BCL10; PLAGL2; TRIP6; MAFG; ZNF593; CCNC; EMX2; SNAI2; TSC22D3; NFE2L1; PTTG1; CREG1; RBM39; EGR3; BRCA1; ZNF281; LITAF; EHF; MITF; SREBF1; CBFB; HEY1; BRD8; HMBOX1; ELF1; SHOX2; TFCP2; INSR; ASH2L; TCFL5; BASP1; CCNH; HMGB3; TOX3; ZBED2; HOXB6; ZBTB18; POU2AF1; CEBPB; HOXC6
Down-regulation	129	NFKB2; TFAP2A; NFE2L2; MNDA; HABP4; RORA; CALCOCO1; FOXF2; ZNF44; TEAD4; CCNA2; ZIC1; ID4; CSDC2; ZFP36L1; ZNF331; ZXDC; KAT2B; FOXF1; ZNF148; ZNF654; TAF12; HOXC10; PHIP; CALR; ZNF611; DACH1; ERBB4; IRF7; CREB3L2; NR4A2; HMGB2; PRRX2; EYA1; ZBTB20; SMAD6; OSR2; ZNF253; NKX2-2; AES; FOXC1; ELF3; CREM; IRF5; ZNF264; TEAD3; TBL1X; PAX6; MAF; SOX10; TULP4; TBX21; KLF2; ZNF665; PRDM2; CD3D; SALL1; LIN28A; SMARCA1; ZNF467; TRPS1; SIM2; URI1; E2F2; TGIF1; OVOL2; RNF4; RARG; SMARCD3; HLF; MYCL; DLX5; RXRA; MXI1; ZNF329; TXNIP; AR; GATA6; BHLHE40; CARHSP1; ESR1; TCF7L1; BHLHE41; POU4F1; GRHL2; EN1; ZNF415; TCF4; ZNF160; CITED2; KDM5D; ELF5; MYCN; PBXIP1; IKZF1; NFATC3; SOX2; CBX7; TLE2; TRIM16; NCOA1; ZNF423; PHF20; NKX3-1; ING2; XBP1; GATA2; CREB1; WT1; ZNF580; HOXD3; ZNF562; TGFB1; DAXX; ZNF512B; PURA; AEBP1; GATA3; THAP11; PEG3; MAGED1; IRF9; SPEN; HHEX; ZNF586; DMTF1; TBX3; TGFB1I1; IRF4