Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76022	Celastrol	GSE92742	MCF10A	Human	24h	0.4uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	199	TAF10; KDM5D; HDAC6; HDAC9; ORC2; RFX7; MED1; HSF2; TTF2; ZFY; PHF8; MEF2C; TP63; RELA; SMARCA2; PCBD1; IKZF5; MTDH; HMGA1; ATF6B; AATF; RUNX2; PATZ1; BAZ1A; EED; MLX; SAP30; HOXA6; MDM4; TRAF6; EGR1; NFKBIB; MAZ; MNAT1; GTF2A1; YAF2; CCDC59; YEATS4; FOXN2; BMI1; SOX15; TFEB; POLR3F; PHF2; STAT6; TAF9; SFMBT1; ETV1; ZSCAN12; MLLT10; TERF2; GATA4; BAZ2A; KAT7; USP22; ZNF143; TBP; TMF1; ELK1; CREBZF; PIAS2; TADA3; KMT2B; ZSCAN5A; DDX5; ARID4B; HEY1; CBFB; GABPA; PMF1; NRIP1; ATF1; CAPN15; TDRD3; FOXO4; CRY1; NPAS2; ERG; SIX2; UBE3A; ERBB2; ZNF532; ZNF432; TSC22D2; ID3; TRIP6; SF1; UIMC1; RFX5; USF2; ZNF384; MED17; HIF1A; CCNC; ZBTB24; ETV4; MED24; C1D; MDFI; MYF6; RNF111; UBE2I; VEZF1; ZNF528; MNT; NFE2L1; BCL10; ADRB2; FOSL1; KAT8; ZBED4; TBL1XR1; TTF1; XRCC6; RCOR3; SPIB; PPARG; TAF4; GABPB1; SMAD5; PTTG1; BRPF1; ZBTB11; NCOR1; PCGF2; KDM2A; HIVEP2; MBD2; BTAF1; PMS1; SIM2; FOSB; ELF1; CRK; FOXA2; HOXA5; FOXD1; ILF2; SREBF1; MMS19; ZFP36L2; TAF1D; NCOR2; ZNF274; PRKDC; RNF6; TFCP2; NR2E1; PSMD9; ATF7IP; HOXA10; ASH2L; ZEB2; TCERG1; ACTL6A; HTATIP2; KAT2A; TSC22D3; KMT2A; NPAT; DDIT3; MYCBP; SUZ12; AGO2; TCF21; IRF8; BCLAF1; BRD8; ZNF302; TRIM29; MITF; RBM39; ASCL1; NEDD8; TSC22D1; COPS2; KLF6; STAT1; VGLL4; IKBKAP; ZBTB18; SUB1; PNRC1; HES1; NR2F2; EZH2; MSX1; SMAD7; EMX2; PPRC1; SIX1; CHD7; PITX1; SOX9; PBX3; MEOX1; SNAI2; TGFB1; SUV39H1
Down-regulation	169	SMARCA1; NFKB2; NFE2L2; RORA; ZFP36L1; ZNF44; ZNF611; RBPJ; KDM5C; ZNF331; ZNF665; CALCOCO1; ESR1; HOXB2; JUN; ZNF682; CSDC2; PCGF3; TCF7L1; NEUROD1; ZNF701; SP3; OSR2; DLX4; TEAD3; MNDA; ZIC1; NR5A1; GATA6; ID4; NR4A2; LPIN2; GATA1; ZNF571; DAXX; CARHSP1; TGIF1; ELF3; ZNF329; TFDP2; ZNF711; ZNF180; IRF6; TBX21; ZNF264; ZFPM2; NR4A3; TBL1X; WT1; FOXF2; AR; PHIP; ERBB4; CD3D; EPAS1; RARG; KLF3; ZNF74; ZNF136; EYA1; CHD4; KLF10; E2F2; NANOG; ZNF117; IRF7; PAWR; GRHL2; FOXJ1; LIN28A; NFATC3; PAX6; PBXIP1; ZNF253; MEOX2; ZNF623; CREM; ZXDC; ZNF423; NR5A2; NHLH1; ZNF43; ZNF273; NFE2L3; MAF; ZNF654; ZNF160; ZNF3; ZNF75D; TULP4; ZNF415; CBX4; NFE2; ZNF91; ATF3; PLAGL1; SALL1; TRPS1; DACH1; HEY2; IRF1; ZBTB20; NR2F6; HBP1; CREBL2; RREB1; NKX2-1; URI1; HOXD3; TCEA2; PRDM2; HOXB5; SATB1; CREB3L2; HOXD1; ZNF606; HIRA; ZNF148; CREB1; TCF4; NFATC1; DBP; REL; ZNF22; GATA2; FOXF1; NCOA2; SOX5; ZNF266; PEG3; ZNF586; LEF1; IKZF1; ZNF721; CITED2; MYCL; NFAT5; EGR2; BACH2; TGFB1I1; MYB; NKX2-2; SOX2; ZNF467; ETS1; SPEN; WNT4; PRRX1; TCF7; DMTF1; IRF9; BCL3; TXNIP; MYBL1; ZEB1; HIC2; HHEX; GATA3; KDM5A; RBBP8; CEBPD; SOX10; ZNF512B; TBX3; KLF4; TFAP2C; IRF4; BASP1; HOXC6