Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76021	Celastrol	GSE92742	MCF10A	Human	24h	2uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	157	TAF10; PHF8; HDAC6; WDHD1; EED; TTF2; BRIP1; MLXIPL; MED1; HCFC2; ELK1; RNF6; HSF2; TSC22D2; ZNF432; FOXI1; FOXO4; TEAD1; UIMC1; RFX7; EGR4; HOXA5; SMARCA5; BAZ1A; SMARCA2; ATF2; MNAT1; CRY1; TBP; PRKDC; MED27; ZBED4; THRAP3; E2F8; ATF1; MLX; CCDC59; ETV4; PHF2; MEOX2; PMF1; PIAS2; YEATS4; MDM4; FOXO1; ETV1; CDK8; LITAF; HDAC9; TRRAP; YAF2; ARID4B; MED24; SAFB2; NRBF2; MKL2; ASH2L; FOXO3; RERE; SSRP1; WHSC1; MNT; SETD2; ZNF84; PPARGC1A; PPARG; TSG101; BAZ2B; ZNF143; POLR3F; ZNF384; ELK3; UBE2I; KAT5; TLE1; DDIT3; RNF4; STAT6; HMGA1; BMI1; VEZF1; TCERG1; KMT2B; RBM14; FOSL1; BAZ2A; MTDH; NR2E1; LEF1; BRF2; TBPL1; SOX15; PCGF2; PSMD9; ZNF165; TBL1XR1; PLAG1; IRX4; KAT6A; BAZ1B; TRIP6; ETS2; CHD7; ZNF410; TSC22D3; RUVBL2; ZBTB18; IKBKAP; KLF6; SMARCA4; CRK; GABPB1; SMARCE1; HOXA7; ZKSCAN1; ASCL1; EMX2; BTG1; MED23; SREBF1; CCNC; SUZ12; RFXANK; HTATIP2; MMS19; RYBP; C1D; ELF1; BTAF1; PLAGL2; TFCP2; PAX5; RNF10; SFPQ; ZBTB11; ACTL6A; TRIM16; ZNF532; VGLL4; HNRNPD; CBFB; MYCBP; PPRC1; MTF2; SHOX2; MSX1; RFX5; ERBB2; PDLIM1; PTTG1; PIR; CTBP2; MAFB; BASP1; NUP62; TSC22D1; CEBPB
Down-regulation	164	CALCOCO1; JUN; NFKB2; KAT2B; LMCD1; NFE2L2; ARNT2; SSBP3; PAX6; DAXX; IRF6; PHF1; EYA1; MAF; NR4A2; DACH1; RORA; DLX4; CREM; TCF7L1; IRF7; PHIP; ERBB4; ZXDC; FOXC1; KDM4C; RARG; CSDC2; ZNF571; PRDM2; HMGN3; AHR; NHLH1; FOXF2; ZNF536; ZNF654; MYCL; GRHL2; CBFA2T3; IRF5; MYBL1; DLX2; TRPS1; GATA6; ID4; FOSL2; ZNF253; ZFPM2; SMARCA1; RING1; TAF12; TEAD4; ZNF768; JAK2; CBX4; SOX10; E2F2; ZNF44; HNF1B; ZNF331; ZNF248; MXI1; PCGF3; NKX2-1; URI1; ZNF264; BHLHE40; KLF3; NFATC3; ZNF623; ZNF665; OSR2; KDM5D; REL; CALR; ZNF136; NR4A3; CAMTA1; ZNF816; BHLHE41; ZNF14; DLX5; THAP11; TXNIP; ESR1; TBL1X; TCF4; ZNF180; CD3D; TEAD3; SP100; TFDP2; CREB3L2; NR3C2; HOXB13; ZNF124; SOX2; ZNF512B; ST18; ZNF329; ZNF423; ZNF467; WWTR1; TBX3; HLF; KLF10; PRDM1; MYCN; ZSCAN31; SALL2; FOXE1; ELF5; EP300; ZEB2; WT1; ELF3; SATB1; POU4F1; TGFB1; CREB1; HOXD1; IRF9; DBP; HOXC10; PHOX2B; CBX7; ZNF148; HHEX; SSX1; BNC2; IKZF1; AEBP1; CREBL2; SLC2A4RG; MLXIP; ZNF580; NCOA1; EN1; TGIF1; PHF20; TGFB1I1; SALL1; DMTF1; SIAH2; ING2; GATA2; HOXD3; EGR2; IRX5; PEG3; KLF13; GATA3; ZSCAN18; NFAT5; MEIS2; IRF4; BCL11A; HIC2; NR1H2; PSIP1; ZNF586; CBX6; TFAP2C; KLF4