Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76020	Celastrol	GSE92742	MCF10A	Human	24h	10uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	168	ADRB2; TAF10; PHF8; HDAC9; HDAC6; NCOR2; MNT; ZBTB16; NPAS2; RNF6; TTF2; TMF1; SOX9; KLF9; SMARCA2; PCBD1; USP22; CDK8; TP63; STAT6; SAP30; HMGA1; RFX7; AATF; MAZ; PRKDC; TRIM29; FOXO1; FOXO4; SIRT7; LEF1; MLXIPL; DRAP1; ZNF432; BTG1; TSC22D2; ZMYM2; NR1I2; CHD9; EGR1; SNAI2; NRIP1; ZNF165; PATZ1; EED; SOX15; MED1; HIF1A; ZBTB7A; ZSCAN18; SMARCD2; CSDE1; DDX5; EWSR1; BAZ1A; CHD8; MITF; ERBB2; GTF2IRD1; ZNF222; ETS2; ERG; FHL2; SPIB; HTATIP2; KLF5; ZNF140; HSF2; EP400; MAFF; ZNF84; ZBED4; BAZ2B; SAFB2; MTDH; PPARGC1A; PIAS2; CRY1; ZNF83; HIVEP2; ZFP36L2; MTF2; GATAD2A; TRIP6; NFE2L1; MDM4; RRN3; CITED1; BCL11B; ZNF131; NCOA3; BAZ2A; TAF1D; MLX; TLE1; MED13; PSMD9; KMT2B; RUNX1; ZNF302; BRF2; TFEB; EHF; CERS6; TSC22D1; MAFG; ARID4B; BRPF1; TCERG1; ZBED2; ZNF532; ATF1; ASH2L; MED17; DDIT3; HEY1; TBP; LZTS1; CEBPG; BIRC2; IFI16; BBX; BTAF1; RYBP; EGR3; SUZ12; FOSL1; MAGED1; CAMTA2; CRK; ZKSCAN1; NR2C1; KLF4; MBD2; MMS19; BACH2; SAP18; ETS1; MED23; RUVBL2; PAX5; KLF7; NEDD8; ZNF267; ZFHX4; FOSB; KDM5D; PPRC1; SREBF1; TCEB2; FOXO3; HMBOX1; UBE2I; VDR; LITAF; KLF6; IKBKAP; NKX3-1; ZHX2; ID3; PCGF2; RFX5; ZBTB18; MSX1; TRIM22; BASP1; FOXG1; CEBPB
Down-regulation	157	JUN; GTF2A2; DNMT3B; NFKB2; ELF3; NFE2L2; DLX4; PCGF3; KAT2B; PAX6; FOXM1; NR4A2; ZNF711; MNDA; WT1; NKX2-1; ZNF331; GTF2I; CREM; ZXDC; FOXL2; SMARCA1; SP3; ZNF571; RORA; WWTR1; SMAD6; TGIF2; HOXD13; SUMO1; RARG; ESR1; NR4A3; GRHL2; ABT1; NEUROD1; RARA; KLF3; SSBP3; ZFPM2; TEAD4; CAMTA1; NR2F1; E2F8; ERBB4; LIN28A; PARP1; SCMH1; NFYA; FOXF2; OSR2; IRF5; E2F2; URI1; IRX5; SOX5; ZNF623; MYBL1; NR5A2; FOXF1; RFC1; GATA6; AR; CD3D; SOX11; POU4F1; ZNF74; ZNF329; ZNF816; NKX2-2; BCLAF1; EYA1; IRF7; CENPF; ITGB3BP; ZNF467; OVOL2; VGLL1; ZNF253; MED21; KLF10; HOXD3; TBX2; ZNF44; TLE2; RNF138; TFDP2; PHIP; IRF4; PAWR; ZSCAN31; MXI1; WNT4; HMGB2; ZNF512B; PRDM2; ZNF136; NR3C2; STAT4; ZNF264; CBX4; NR1D2; AHR; HHEX; SATB1; DACH1; CREB3L2; TCF4; PEG3; CNOT3; IKZF1; DAXX; TRIM24; NFE2L3; ZNF217; HOXB2; CCNE1; REL; HLF; HOXA5; MAF; XBP1; TBL1X; DBP; ZNF124; ZNF586; DLX5; GATA2; ID4; SOX2; CREBL2; ZNF22; TRPS1; MECOM; TOX; PHF20; TERF1; CITED2; TFAP2C; EYA2; FOXC1; NR1H2; SATB2; CREB1; GATA3; TGFB1; SUB1; HOXD1; HOXB7; SALL1; SPEN; DMTF1; PSIP1; BHLHE41; KAT6B; ATF3; MEIS2