Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76013	Chir-99021	GSE92742	MCF10A	Human	24h	2uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	178	TAF10; HDAC9; HDAC6; TTF2; HCFC2; PIAS2; EGR4; PCBD1; WDHD1; RFX7; MNAT1; SMAD2; HOXA6; HSF2; TFAM; BRIP1; AATF; YEATS4; TAF9; ZNF143; CRY1; SAP30; NFKBIB; ATF2; MED1; ARNTL; PHF8; MTDH; BLZF1; PDLIM1; EED; RNF141; PMF1; XRCC6; THRAP3; TMF1; MLXIPL; TDRD3; CSDE1; MED4; MED7; ERG; FOXO1; BAZ1A; ZBED4; TSC22D3; TBP; ETV1; BMI1; RSF1; C1D; CREB3; GABPA; MBD2; MLX; MED17; HTATIP2; ZNF576; CTR9; MDM4; PRKDC; NCOR2; KMT2B; ILF2; POLR3F; CREBZF; ELK1; RRN3; NR1I2; ASCL1; ATF1; MED27; ADRB2; SREBF1; THAP1; VPS72; PATZ1; HIF1A; RNF6; MDFI; TRRAP; SMAD5; RYBP; UIMC1; TSG101; ASH2L; RNF138; PCGF2; ARID4B; MEF2A; PTTG1; ZNF165; PEX2; UBE2L3; RFX5; ZBED2; BRF2; MED21; UBE2I; CCDC59; ZBTB16; NFIL3; USP22; STAT6; MAFF; ZNF432; NR2E1; CBFB; ACTL6A; SOX15; ZNF302; LZTS1; BAZ2A; MED24; MNT; BTAF1; FOXO3; EMX2; MED6; COPS5; CLOCK; CCNC; NPAS2; ZNF267; DDIT3; PAX5; FOSL1; TAF9B; CRK; RFXANK; SUB1; MYCBP; ID3; CEBPG; TCERG1; MEOX1; TSC22D2; TLE1; PCGF1; GATAD2A; SAP18; SUZ12; NPAT; HOXA5; SIX2; TBPL1; EZH2; PIAS3; GABPB1; RBM14; NEDD8; ING3; IKBKAP; FOSB; NFE2L1; ZNF532; RBM39; MED23; SMAD7; MAFB; RHOA; ETS1; SCAND1; ETS2; TRIM29; TSC22D1; BRCA1; RBBP8; SIX1; NRIP1; SMAD1; ATF5; PSIP1; SNAI2; EGR3; TOX; MSX1; CEBPB
Down-regulation	183	JUN; PHIP; NFKB2; CALCOCO1; MNDA; ZNF611; NFE2L2; KAT2B; ZXDC; ZNF331; PCGF3; ZNF44; IRF7; PAX6; SMARCA1; SP3; OSR2; CREM; EYA1; FOXF2; NR4A2; TFDP2; ZNF160; NR1D2; DAXX; ZNF665; ZNF264; ID4; ZNF136; PHF1; RREB1; SSBP3; RORA; ZBTB20; URI1; ZNF329; ZNF444; BACH1; GRHL2; ZNF701; RARG; CAMTA1; AES; KDM5C; IRF6; LIN28A; GTF2I; TBX21; ZFPM2; TGIF1; ZSCAN18; TCF4; CBX7; SP100; REL; MYCL; ZIC1; ZNF430; SMARCC2; MGA; TEAD3; TCF7; NEUROD1; E2F2; MXD3; ELF3; MYBL1; TULP4; POU4F1; HOXC11; PSMD9; TXNIP; FOSL2; CTBP1; ARNTL2; ZNF253; ZNF446; ZNF623; MAF; OVOL2; SIAH2; FOXF1; ZNF587; TGFB1I1; ZNF148; FOXC1; HIVEP1; MXI1; ZNF274; PHF20; JAK2; ERBB4; ARID5B; ZNF43; HOXC10; ATN1; BTG1; PRDM2; CBX4; ZNF816; DBP; ZNF721; ZNF512B; ZNF580; IRX5; ZNF606; TRPS1; TFAP2A; RING1; SALL1; CD3D; KLF3; NKX2-1; ZNF551; ZNF586; IRF5; HOXC4; ZBTB38; SIM2; TBX3; HDAC4; PBXIP1; SATB1; NR4A3; TCF7L1; ZSCAN31; ZFHX3; IRF3; PRDM1; CREB3L2; IKZF1; ZNF652; AHR; HLF; ZNF117; HHEX; FOXE1; ZNF124; ZNF273; CALR; NFKB1; EP300; NFAT5; HIC2; NR3C2; NKX2-2; ZNF266; PEG3; DLX5; HOXC6; AR; ZNF419; CREG1; SLC2A4RG; BHLHE41; NCOA1; TFAP2C; PRRX1; GATA6; HSF1; BASP1; ZEB1; XBP1; ESR1; GATA2; NCOA4; REPIN1; MEIS2; MYB; ID2; SPEN; TGFB1; TBX2; SOX10; HOXD3; THAP11; NR1H2; JUP; GATA3; IRF4; NFATC3; IRF9; MECOM