Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76003	Bms-509744	GSE92742	MCF10A	Human	24h	0.4uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	140	HDAC6; TAF10; HDAC9; HEY1; TTF2; STAT6; PCBD1; PHF8; YEATS4; PRKDC; MED1; EGR4; ASCL1; INSM1; BAZ1A; RRN3; ERG; MNAT1; HOXA4; MTDH; HSF2; TRIP6; CHD9; ZNF432; CCDC59; TWIST1; LOXL2; HTATIP2; RFX7; MLXIPL; ETV1; SMAD2; FOXA1; PTRF; TMF1; CEBPD; TAF11; ATF1; SOX17; NR0B2; ARID4B; AATF; ZNF224; BAZ2A; HOXA5; CUX1; WDR77; TFAM; MDM4; USP22; HIF1A; ZNF140; RYBP; SMARCA2; ASH2L; ACTL6A; CSDE1; ZNF165; TLE4; NRIP1; NCOA3; ARID1A; KLF7; SOX15; SPDEF; CRYM; SOX9; ECD; RB1; BRF2; MSX1; RFX5; ZHX2; PCGF2; HMGA1; SP2; PSMD9; ETS1; MED4; EMX2; TFCP2; ETV5; NR4A1; SUZ12; NR2E1; PMF1; NEDD8; KMT2B; NCOR2; FOSL1; COPS5; TP63; SUB1; CNOT2; KAT2A; FOSB; TSC22D2; TBPL1; NPAS2; GABPB1; SNAI2; RAD21; MYCBP; SALL2; EGR3; MED23; EZH2; CRK; TSC22D3; TCERG1; RNF6; TRIM22; CTR9; TBP; ID3; SIX2; INSR; PTTG1; YWHAB; FOXO1; ISL1; MED24; NFATC3; FOXD1; MEIS1; PRRX1; PEG3; TRIM29; ZNF131; PPRC1; ZBED2; SIX1; VDR; IKBKAP; TSC22D1; ZBTB18; IRF8; PSIP1; MEIS2; FOS
Down-regulation	159	SP3; NFKB2; NFE2L2; HOXC10; DNMT3B; ZXDC; RORA; PCGF3; ZNF331; KDM4C; BACH1; ZNF253; USP21; KAT2B; ZNF211; PMS1; ELF3; ZNF329; CALCOCO1; SMAD6; EYA1; RXRA; SIAH2; ZNF571; TFDP2; KLF11; MED12; PRRX2; BANP; HOXC11; NFX1; RBPJ; IRF5; OSR2; BRD3; ZNF227; ZBED1; POU4F1; PRDM1; HOXA1; IRF7; MAF; NCOA1; ZNF133; AR; NR4A2; HDAC4; LIMD1; FOXJ2; ZFP36L1; PAX6; TEAD3; NR1D2; ZNF93; FOXL2; MGA; ESR1; CDYL; GATA6; OVOL2; NR1H3; GRHL2; PRDM2; PHF20; ZNF264; TXNIP; ZNF665; XBP1; LIN28A; MNDA; HMGN3; SCMH1; CREBL2; IRF6; ZNF273; SATB1; TGIF1; PHIP; HOXD3; CREM; IRX5; ZNF419; NFE2L3; PLAGL1; DBP; PBXIP1; ZNF606; BHLHE40; EP300; TBL1X; SSBP3; ATF4; HMGA2; CIZ1; MYCL; DNAJC1; GATA2; IRF3; HDAC3; ZNF134; TCF7L1; ZNF148; E2F2; CBX7; URI1; DLX2; WT1; NKX2-2; SALL1; CBX4; PLAGL2; ZIC1; CREB1; RREB1; HOXC6; ZNF43; ZNF586; ARNTL2; ZBTB1; KLF2; CARHSP1; MXI1; STAT3; ZNF580; BCL3; KDM5D; DAXX; TCF4; TERF1; ID4; THAP11; MYB; TLE2; CITED2; DLX5; SCAND1; ING2; HIRA; FOXC1; IKZF1; ZNF266; KLF4; DMTF1; NR1H2; ZNF124; ATF5; FOXF1; TCFL5; IRF4; GATA3; MAFB; SOX10; NR2F2; CREB3L2; ERBB4; FOXG1; BASP1; KAT6B; TBX3