Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75997	Bix-02189	GSE92742	MCF10A	Human	24h	10uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	99	TAF10; ZFP36L2; ZNF226; TCF15; RCOR3; SIRT2; CREB5; RRN3; TRIM16; ELK1; PHF2; MBD2; SAP30; GMEB2; ZNF224; HR; ALX1; ILF2; MED23; SUPT3H; MED17; USP22; ABL1; ENO1; DDIT3; UIMC1; MAZ; HOXA10; ZNF135; MED24; ZNF143; MEF2D; TP63; ZKSCAN1; LMCD1; ERG; MTA1; PITX2; SIX2; MED1; HTATIP2; MED27; CERS6; RBBP4; PRKDC; LITAF; MEOX2; HIPK3; SMARCA2; TWIST1; PNRC1; TSC22D3; NEDD8; ZNF302; SMAD4; TFCP2; ZNF32; ATF1; MLX; ZNF532; FOXA1; ZNF274; ARID4B; PSMD9; HSBP1; STAT6; TBP; EN1; PSMC3; TLE4; PMF1; PHF20; SND1; TBL1XR1; NPAS2; ASCL1; TSC22D1; FOXD1; BCL11A; TSC22D2; ZNF22; UBE2I; TOX3; GABPB1; TLE1; PFDN5; PBX3; AHR; E2F6; CRK; EDF1; EMX2; STAT1; IKBKAP; TCERG1; SNAI2; SPEN; CEBPB; TRIM22
Down-regulation	134	TBL1X; SP3; CALCOCO1; MXI1; MYCBP; ESR1; IFI16; PAX6; NEUROD1; BNC2; ELF3; EZH1; SP100; MITF; RBFOX2; IRF3; FOXF2; DAXX; ZXDC; NFE2L2; NAB1; TFCP2L1; ZNF44; RBBP7; ZMYND8; ZNF552; NCOA2; NFKB2; ZNF580; ZNF331; ARNTL2; ATF4; HMGA2; FOXF1; WWTR1; OVOL2; TGIF1; RREB1; SMARCA1; TEAD3; ZNF148; ZNF415; RBPMS; IRF9; NR4A2; TGFB1I1; ZNF444; TCF20; PLAG1; ERBB4; BCLAF1; ETV5; ETS1; CREB3L1; VPS72; RARG; NFATC3; ZNF136; MEIS1; CARM1; MAF; FOSL2; WNT4; PIR; TXNIP; TAF5; CARHSP1; OSR2; TLE2; E2F2; HOXA5; CBX7; KMT2A; CITED2; SIAH2; ELK3; KLF3; SIN3B; ZBTB1; INSR; BRD4; ZNF419; CREM; KAT6A; SOX5; MECOM; SATB1; DBP; GRHL2; SALL2; AR; TRPS1; HMGN3; BBX; ZFPM2; CCNH; ATF5; NR1H2; NFIB; JUNB; RUNX3; STAT5A; PURA; KLF5; THAP11; HOXC4; POU2AF1; IRF4; ZBTB38; MEIS2; TCF4; MECP2; ZNF266; NR2F2; SOX2; ZNF264; SALL1; CBX6; ZNF586; ID4; WT1; TCFL5; GATA3; PEG3; MYB; KAT6B; EGR2; SMAD7; HOXB7; TBX3; IKZF1; TGFB1; FOXG1; ATF3