Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75995	Afatinib	GSE92742	MCF10A	Human	24h	2uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	161	TAF10; FOXO4; ADRB2; NCOR2; HDAC9; HDAC6; FOXO3; TSC22D3; ERF; KLF9; PHF8; TERF2; ING4; CDX2; ZBTB16; PBX1; ZNF224; ZKSCAN1; BTG1; SIRT7; RSF1; PPARGC1A; PDLIM1; MLXIPL; CREB3; TTF2; SMARCD2; ZNF195; ZMYM2; TADA3; TRIP6; PBXIP1; ZNF394; ZFP36L2; NFE2L1; MKL2; BRD2; RELA; SIRT2; CREBL2; MED13; CREG1; PFDN5; HTATIP2; ID3; PRKDC; NCOA3; ZNF669; TDRD3; EHF; ZNF165; FOSB; TCF7L2; JUND; PGR; ELF4; TFEC; SMAD2; TAF4; EMX2; TLE1; ELK1; CHD4; NRIP1; ZIC1; NR1I2; MEIS1; FOXO1; INSM1; MITF; RFX5; CRYM; VEZF1; PIAS2; TP63; PMF1; SREBF1; VGLL4; MED1; ATF1; ZNF34; NAB1; SMARCA2; RNF6; MED24; GTF2F1; NFKBIA; ZNF432; RFXANK; LITAF; MBD2; CCNH; MLX; CTBP2; SOX17; ZBTB43; CUX1; JUNB; BAZ2A; NFIL3; STAT6; ETS2; BACH2; LEF1; NR2E1; LOXL2; MTDH; USP22; CUX2; KAT2A; KAT5; TRIM29; ZNF302; CDK9; ARID4B; OLIG2; CERS6; MYB; SCAND1; MAZ; VDR; HIPK1; RBL2; ZNF83; RUNX1; TWIST1; TP53; ELF1; CEBPD; USF2; ZHX2; SMAD1; HOXB13; NCOA2; CRK; PNRC1; SSX1; ZNF652; ID1; ATF5; COPS2; RBM39; TCFL5; ZNF91; ZBED2; ZNF721; SATB2; TCEB2; SMAD7; SNAI2; MAFB; TFCP2; JUP; PCGF2; E2F3; SUZ12; MTF2; HOXB6; TSC22D1; ATF3; CEBPB
Down-regulation	165	CCNA2; TBL1X; FOXM1; GTF2A2; CENPF; EYA1; NFKB2; WWTR1; RORA; KDM5D; TAF1A; SP3; HMGB2; CAMTA1; BCLAF1; GTF2I; PAX6; BACH1; MXD3; E2F2; RFC1; MNDA; ZXDC; DAXX; CHAF1B; NFE2L2; SMARCA1; URI1; FOXF2; GCFC2; ZNF710; KLF3; BHLHE40; PCGF3; RXRG; ZNF711; ID4; ZNF329; SIAH2; TRIM25; VGLL1; CCNE1; CALR; DNMT3B; NR1D2; ABT1; HMGXB4; HMGA2; TRIM32; NR2F2; ARNTL2; SIM2; ELF2; EN2; ZNF331; CD3D; TULP4; ZNF654; HNRNPD; SERTAD2; HOXA5; EZH2; MEOX2; ZNF253; CREM; LIMD1; NR2F6; CBX3; HOXC10; ING1; ZEB1; SSBP3; CREB3L2; NR2F1; RNF4; ETV4; CDYL; CHD1; PEG3; USP16; RARG; ERBB4; MYCL; AGO2; CARM1; TGFB1I1; NR4A2; TAF9B; HLF; HOXB2; MGA; NFATC3; ETS1; XBP1; NKX2-2; NR4A1; ZNF239; CARHSP1; WWP1; CBX5; IRX5; SUV39H1; CNOT3; PRDM1; HDAC3; ZFPM2; BRCA1; GABPB1; POU4F1; PLAGL1; ZNF22; HLTF; EP300; IL16; TRIM28; DBP; KAT6B; HOXC6; ZNF586; SATB1; ZMYND8; HHEX; TBX3; NKX2-1; TLE2; PHF20; MYCBP; YWHAB; EN1; TLE4; DLX2; MYBL1; EGR2; ELF5; GATA3; TGIF1; TRPS1; SOX11; ZNF131; SOX10; ZNF443; DLX5; AHR; IKZF1; HOXD3; BHLHE41; NFKB1; HIC2; CBX6; FOSL1; GRHL2; OSR2; SALL1; SPEN; PSIP1; PTTG1; MEIS2; HMGB3; IRF8; SOX9; HOXB7; TCF4; IKBKAP; IRF4; RBPMS