Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75994	Afatinib	GSE92742	MCF10A	Human	24h	10uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	212	FOXN3; ZNF430; KLF9; CALCOCO1; ZNF112; TTF2; ZNF117; ZNF224; HDAC9; MAML1; REL; ZNF665; POLR3C; ZNF611; ZNF91; SIRT7; ZNF93; EHMT2; ZNF394; ZNF668; GLI2; PBXIP1; CDK8; MED13; ZNF768; ZNF43; HIVEP1; HDAC6; RSF1; ZNF44; TSC22D3; HINFP; NPAS2; CRYM; ZNF85; PAX6; ETS2; HOXD1; E2F8; TCF3; BCL11A; PLAGL1; SOX13; BNC2; THRA; NR4A1; BAZ2A; ELF4; TBX21; BCL6; BTG1; CUX1; FOXI1; KDM5C; ZNF354A; BLZF1; UBE2L3; NR4A3; RARB; ERF; PIAS4; ACTL6B; TULP3; ZKSCAN4; KLF5; ZNF175; IRF9; DACH1; NCOA1; SPIB; ZNF12; CNOT6; ZNF160; ZNF652; MED21; ZNF124; ZBTB16; JAK2; CAPN15; FOSL2; TP63; PRKDC; ZNF222; NCOA3; CERS6; GTF2F1; ZNF264; SIRT2; MEF2D; ZBTB43; ARID5B; PSMC3; NOC2L; PRMT2; JUNB; ZNF189; TULP4; MEIS2; EP300; PBX2; PRDM10; EYA1; ARNT; ST18; TAF11; ZHX2; GATA6; ZSCAN18; ZNF536; MZF1; CEBPD; ZBTB44; FLI1; ZNF669; CBFA2T3; ZNF551; INSR; ZNF423; TOX4; RING1; LEF1; TCF7L2; RBL2; ZNF468; HBP1; SUPT7L; SAFB2; GTF2IRD1; CBX7; ZNF195; RCOR3; NR0B1; NAB2; SCMH1; SMARCA2; ZFX; TFAP2A; ZNF574; BACH2; CDIP1; CREBL2; ZKSCAN1; ZNF232; TCEA2; CREM; GATAD2A; NR4A2; MYT1L; RBFOX2; SOX17; SND1; ZBED4; ZNF667; CREB1; NCOA2; THAP11; CREB3L2; EHF; ERBB2; HIRA; ETS1; IFI16; PLAG1; NEDD8; SHOX2; ZIC1; ZNF529; TRIM29; PNRC1; RFXANK; TWIST1; MXD4; HSF1; PITX2; MED15; ELF3; ZNF136; LITAF; HOXD3; ZNF586; FOXO3; AES; HIC2; TRIP6; SLC2A4RG; VPS72; KLF7; ATF7IP; JUND; ZSCAN31; MTA1; FOXF1; TAL1; ZNF721; TLE1; ZBTB38; CTBP2; FOSB; HMBOX1; ZNF331; MYBL1; MECP2; SOX9; KLF13; MNDA; PITX1; ZNF512B; NR2F1; SNAI2; ID1; CRK; CEBPB
Down-regulation	186	CCNA2; GTF2A2; HDAC2; CENPF; USP22; BATF3; GTF3A; CALR; ZNF672; PTRF; CEBPZ; SMARCA5; MEOX2; MBD2; MYC; FHL2; PHF20; RBPJ; RAN; ZNF783; TAF10; LPIN2; BCLAF1; CBX3; KDM5D; RBBP7; POLR2A; SMARCA4; HLTF; CCDC59; ELK3; DRAP1; AATF; EZH2; NFYB; SMARCE1; PARP1; NFIB; DNMT3B; CARM1; ZNF23; NR2F2; YBX1; ATF5; ESR1; HLF; ZFP36L2; RELA; HSBP1; PREB; FUBP1; PTTG1; PPARG; TFDP2; ZNF3; NFATC3; HOXB2; ZNF552; ETV5; FOSL1; XBP1; GCFC2; DEK; BAZ1B; SCAND1; CBFB; MLX; UBP1; PIR; DNAJC2; PMS1; SETD2; ARNTL; ADNP; HMGA2; PIAS1; RORA; CNBP; NKX2-2; NR1H3; PSIP1; ID4; PEX2; ETV4; SPEN; YWHAB; TBP; ASXL1; KAT6A; MYCBP; HOXD11; ZNF410; SUV39H1; E2F3; STAT6; ZNF22; KAT8; ZNF528; HMG20A; BIRC2; AHR; EGR2; PPRC1; NCOA4; PDLIM1; TBL1X; CHD4; JARID2; BRD4; ZNF835; SOX15; SIAH2; TRIM28; TBPL1; MMS19; MAGED1; ZNF692; IL16; BRD7; SERTAD2; ZBED2; NAB1; HOXC6; SATB1; E2F5; TRAK1; MED4; ASH2L; CD3D; NFKB1; ZBTB1; MYRF; NKX2-1; ZNF146; SMAD1; FLNA; C1QBP; ZMIZ1; RBM14; LOXL2; ZNF266; ATF4; BRD8; NUP62; BHLHE40; CHD7; KAT2A; TCFL5; SOX11; TCF12; ARNTL2; ELF1; MAF; KLF10; RNF10; HNRNPD; MYB; SFPQ; HMGB2; SUB1; CEBPA; NRIP1; NFKB2; ING2; ZMYND8; RUVBL2; ARID4B; RBPMS; MAFB; WT1; GATA2; SOX10; KDM5A; ELF5; RHOA; ID2; BHLHE41; SMARCA1; MSX1; HHEX; ATF3; GATA3; BASP1; ZNF131; MECOM; PUF60