Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75993	Azd-5438	GSE92742	MCF10A	Human	24h	0.4uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	134	BRIP1; TDRD3; TP63; MLLT10; ERF; RERE; BRCA2; TTF2; HDAC9; ZFP36L2; EN2; ZNF131; ETV4; SMARCD3; CTCF; HLF; ETV5; USP21; CAMTA1; PRDM10; GCFC2; FOXJ3; BACH2; MDM4; ZNF217; SP140; MEIS1; SAP130; POLR3C; BAZ1B; NOC2L; TAF1A; ZBTB7A; TAF4; TBL1XR1; SUPT3H; SMAD4; SIX2; YEATS4; ERBB2; VEZF1; TCF25; TLE1; ATF1; BHLHE41; KAT2B; BMI1; ZNF248; TAF9B; MYBL1; ABL1; HES1; SMARCA2; NHLH2; HSF2; YWHAB; ADNP; RFX7; PURA; ZNF212; MED13; MKL2; NR1H4; ID1; PRPF6; BAZ1A; MED14; STAT1; HOXD11; SAFB; HOXD1; TSC22D2; LZTS1; TSC22D1; STAT4; TSG101; ARID4B; ZNF467; HOXD10; ZNF239; GATAD2A; DNAJC1; CRY1; AES; HOXA5; REL; MEOX1; BCL11A; ZBTB11; MBD2; RBBP4; EYA2; DMTF1; EP300; KMT2B; ZNF512B; NR3C2; BCL11B; EN1; NR4A1; SP140L; MNDA; BTAF1; SND1; PPRC1; CHD1; RBM14; BCL10; MLXIP; IRF4; RNF138; DLX2; FOXD1; TCFL5; TLE2; KAT6B; CREB3L2; SNAI2; SUZ12; SATB2; SIX1; MEIS2; ZBED2; HOXD3; ACTL6A; CRK; ID4; IKBKAP; FLNA; POU2AF1; TRIM22; SATB1; FOXG1; CEBPB
Down-regulation	182	TFDP1; BBX; SETD3; ZNF148; TRIP4; MYCBP; THAP4; ZFP36L1; ZNF552; ZNF136; ZNF350; HIPK2; BRD4; ZNF672; PBXIP1; ZNF226; NRBF2; TFCP2L1; CENPF; SMARCA5; CALCOCO1; ZBTB43; POLR2A; PPP1R13L; OSR2; NFIB; SOHLH2; AR; ARNT; SP110; DNMT3B; HAND1; SP100; CTBP1; RBBP7; INSR; TRIM16; PLAG1; NFIX; SIM2; PIR; LDB1; HOXC11; CDK8; WWTR1; NELFB; ZBTB38; HOXC10; ZNF8; BIRC2; ZNF432; ING2; ZNF415; ZSCAN32; BTG1; CHD4; TFDP2; ZNF629; CREB1; ZNF200; PLAGL1; HDAC1; STAT3; BRD3; IRF6; NONO; ZNF211; ZNF264; ESR1; HMGB2; ZBED1; TBL1X; CERS6; THAP11; BNC2; PCGF2; TBPL1; KLF7; KAT6A; TFEB; ZNF816; VPS72; PSPC1; LIN28A; HOXC6; SMAD6; ZNF165; ZNF587; PLAGL2; SIAH2; ZNF180; ZSCAN18; GATA3; ZNF606; ZNF468; NFYC; NFE2L1; ZNF586; MYRF; ZMIZ1; ZBTB20; RBPMS; ZNF134; AFF1; NR1H2; MTF2; TCF12; STAT5A; IRF5; TSC22D3; YAP1; ZBTB1; MXI1; JUND; FOXO1; ZIC1; RBFOX2; ASCL1; PREB; PHF20; GRHL2; BAZ2B; ZNF544; EMX2; HLX; SAP18; ZNF562; ZNF419; SMAD3; RLF; TCF21; CRYM; LYL1; TXNIP; FOXO3; CTBP2; STAT6; TP53; MYB; CARM1; ATF5; E2F3; ETS1; AGO2; HOXC4; ARNTL2; ZNF304; IRF8; ELF1; ZNF274; ZNF331; ZNF721; CHD3; RFX5; MTA1; NKX3-1; ZNF266; NCOA4; AHR; PAX8; SMARCA1; KLF13; ZNF580; PBX3; MAFB; JUP; KDM5D; PDLIM1; PBX1; SMAD1; EGR2; HOXB6; TOX; IKZF1; IRX5; FOXF1; EGR3; GATA6; TFAP2C; GATA2; TBX3; BASP1