Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75992	Azd-5438	GSE92742	MCF10A	Human	24h	2uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	166	HDAC9; RFX7; INSM1; ZNF195; HDAC6; TTF2; GLI2; TFAM; BRIP1; ZFP36L2; FOXN2; RELA; HSF2; ZNF140; NCOR2; PBX3; MDM4; AFF4; TAF9; PATZ1; HOXA6; ZNF282; TAF10; ZNF274; MXD1; ZBED4; EED; ZNF84; MED17; GABPA; ZNF669; CAPN15; PRKDC; POU3F2; MTDH; MYBL2; RRN3; MED1; FUBP1; ERF; TDRD3; BAZ1A; RYBP; EGR4; MED13; SMAD2; MMS19; ZMYM2; ERBB2; HEY1; MNAT1; POLR3F; HOXA10; TRIM29; UBE3A; ZBTB24; ZNF432; CREB3; HOXA4; GTF2A1; CRY1; BAZ2A; CREB5; CBFB; PPRC1; TP63; CREBZF; YEATS4; ZKSCAN1; ZNF12; CHD8; FOSL1; CUX2; GATAD2A; ZNF557; NRIP1; NR2E1; HOXA7; PAXBP1; TAF1D; XRCC6; MLXIPL; SOX9; ZNF337; THAP1; OLIG2; KMT2B; ASCL1; JUNB; NR1I2; MED24; CITED1; BAZ1B; BRD4; TSC22D2; ZNF692; LEF1; MED27; TRRAP; SSRP1; NCOA3; ADNP2; TBP; USP22; ZNF551; SP2; BRWD1; PCGF1; KAT2A; RFXANK; ZNF131; ARID4B; ETS2; ERG; TRIP6; NPAS2; MTF2; CRK; ZNF544; ING3; BMI1; SAP18; ZBTB11; CUX1; ZNF394; RBM14; NLK; DLX2; DACH1; NFKBIA; MLX; ZBED2; TSC22D1; UBE2I; HTATIP2; IKBKAP; ID1; SFPQ; TCERG1; ZNF83; ZMIZ1; PSMD9; PCGF2; CCNC; CLOCK; PREB; EZH2; ZNF302; ZNF652; SUZ12; KLF13; FOSB; RFX5; SREBF1; ASH2L; FOXO3; KLF5; SNAI2; LITAF; PTTG1; SMAD7; IRF8; EMX2; BCL11A; SPEN; FOS
Down-regulation	157	SP3; CALCOCO1; ZFP36L1; TBL1X; LPIN2; PCGF3; RORA; TEAD3; PLAGL1; KAT2B; NFKB2; KLF2; PPARD; FOXJ1; EYA1; OSR2; ZFPM2; CIR1; SMARCA1; ELF3; CREM; DAXX; ZKSCAN3; TRIM32; HLF; ZSCAN31; BACH1; IFI16; ZNF611; E2F2; FOXF2; ZNF571; LIMD1; LIN28A; MNDA; AHR; NR1D2; FOXF1; MAF; CBX8; SP110; PBXIP1; TXNIP; RBPJ; BTG1; TBX21; ZXDC; CREB3L1; PITX1; TGIF1; SP140; ZBTB38; CDC5L; HEY2; ZNF665; BANP; HMGN3; NKX2-1; ZNF253; OVOL2; RNF4; NFE2L2; EZH1; PRDM2; NR3C2; MXI1; CARHSP1; PIR; TFDP2; CTNNB1; SALL1; ID4; ZMIZ2; GRHL2; SP100; PHF20; NR2F1; NANOG; ZMYND8; TRPS1; MXD4; HOXD3; IRF5; ZFHX3; ERBB4; GATA6; KLF3; SMAD6; SP140L; ZNF423; RBBP7; KDM5D; CBX4; CREBL2; WT1; ESR1; BCL3; EHF; HMGB2; NCOA4; TCF7L1; IKZF1; TCF21; MEIS2; TFAP2C; HHEX; KLF4; IRF4; MYCL; ZNF160; ZNF331; BASP1; IRF7; TCF4; AR; HOXB2; CARM1; SATB1; NR1H3; ARID5B; ZBTB20; EGR2; CBX7; DBP; SIAH2; ID2; TGFB1I1; NR4A2; ELF5; SOX10; KDM5A; TRIM22; E2F5; DMTF1; STAT5B; HIC2; PEG3; FOXC1; TBX2; CBX6; ZNF586; ELK3; NFIB; CREB1; GATA3; MECOM; CEBPD; TCF7; IRX5; GATA2; ZNF264; DLX5; JUP; ATF5; TOX; NKX3-1; HOXC6