Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75991	Azd-5438	GSE92742	MCF10A	Human	24h	10uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	215	HDAC9; ZNF589; EGR1; MDM4; ERF; NFATC4; PBX3; ZNF432; CUX2; ZNF557; PGR; SOX15; ASCL1; ZNF529; ZNF460; RFX7; HMGA1; ID3; SUPT3H; ZKSCAN8; SOX17; BNC1; MYEF2; FOSL1; DRAP1; POU3F2; FEZF2; OLIG2; ZNF225; EGR4; ELF4; DMRT1; NHLH2; ZIC3; ZFP36L2; HCFC2; CCNT1; HDAC6; JUNB; PEX14; INSM1; AFF4; TAF4B; ATF2; BAZ2A; GMEB2; RELA; TAF10; FOXN2; PSMC3; ZNF426; GFI1B; ZNF155; SCAI; TTF2; KAT8; PKNOX2; ZNF623; ZNF528; TSG101; ZNF345; POU4F2; ARID3B; ZHX3; GATA4; NR4A3; CBFA2T3; TFEC; ACTL6B; BCL10; ZNF222; SAP18; AATF; BRF2; TFEB; NRIP1; RNF111; SOHLH2; PBX1; KLF10; PROX1; EZH1; ZKSCAN1; TAF9; TDRD3; CDX1; TOX; THRA; GTF2F1; MYT1; BRD4; TAL1; SPDEF; CDIP1; ZNF165; PRKDC; MLX; CAMTA2; ZNF274; PAX6; SP2; USP22; NCOR2; SND1; SSX1; MYCN; ZNF552; L3MBTL1; ZNF195; MED1; ST18; MED27; ZNF177; HMBOX1; SMAD2; ZNF232; ZNF175; SUPT5H; TCF21; MAFF; ZNF394; BHLHE40; ZSCAN18; KLF7; MDM2; FLI1; NR2E1; MED24; KLF13; INSR; RYBP; ETS1; SRF; C1D; FOXA2; ZEB2; LMCD1; PRDM2; ARID1A; THAP1; RNF6; EGR2; NR1I2; LITAF; ZNF532; HEY1; ZBTB43; ZBED2; ZNF34; NCOA3; TWIST1; RAD21; ZNF136; ZNF91; ZNF7; SATB2; SUPT7L; DLX2; FUBP1; ZNF574; EMX2; DACH1; CNOT3; TCF12; LZTS1; ISL1; ZNF24; HOXB13; RLF; MMS19; RHOA; ZNF415; PPRC1; SALL2; BHLHE41; HSBP1; NPAS2; NR1H3; TDP2; ZNF131; MYCBP; ASH2L; LEF1; VPS72; PMF1; ZNF587; EGR3; ZNF423; HLX; MEIS1; HDAC1; ING3; PFDN5; ENY2; PDLIM1; RB1; AIP; RFXANK; MTA1; CLOCK; ZNF267; SNAI2; TCERG1; ZNF562; FOSB; SUZ12; CRK; ID1; PRRX1; SMAD7; ESR1; SUV39H1; NUP62; MAFB; CEBPB
Down-regulation	235	MYC; SP3; NFE2L2; HDAC2; TBL1X; CDK7; CCNA2; GCFC2; RORA; FOXM1; TEAD3; ZFP36L1; KLF2; RFC1; HLF; CHAF1B; NFKB2; HLTF; SMARCD2; HOXC10; SMARCC1; PCGF3; SAP30; HOXA5; EYA1; BRD3; SMARCA1; CALCOCO1; RERE; ZNF76; CBX3; SMARCA5; DEAF1; ZBTB20; CITED2; CEBPZ; BAZ1B; SIX2; NFIL3; VGLL4; NONO; BCLAF1; IRF7; PHIP; NFIC; CENPF; IRF2; HDAC7; HMG20B; HMGN3; STAT4; ZXDC; EZH2; ELF3; TP53; CEBPE; NFE2L3; CARHSP1; ING1; NCOA4; ETV6; TSC22D3; CASZ1; ZBTB38; NR1D2; DNMT3B; KDM5D; YBX3; TBX21; SOX11; THAP4; NR1H4; GRHL2; AHR; CREM; HOXC4; BTG1; TRIP4; GTF2IRD1; NFIB; CIC; TGIF1; PRRX2; HOXC6; NR2F2; RBL1; WWC1; ZNF672; ZBTB1; BACH1; HOXC13; HOXC11; LIMD1; ARID4A; SP110; SP100; HOXB2; ZBTB14; FOXF2; REL; PLAGL1; DAXX; DYRK1B; NELFB; URI1; MXD3; TAF5; ZSCAN31; HES1; KDM2A; E2F2; HMGB1; CENPB; FOXK2; IFI16; WWTR1; PTRF; NFATC3; ERCC3; IRX5; CREBZF; ING2; MAF; KAT2B; NPM1; ABT1; TCF20; BANP; RBBP7; ZNF292; ZNF446; ARNTL2; BBX; MYBL1; CAMTA1; SATB1; RBBP5; DDX5; SCMH1; GLI3; ZMYND8; PRDM12; LPIN2; CNBP; HDAC4; MGA; RBBP4; SPEN; MXI1; ZNF180; TOX3; ID4; ZNF184; PITX1; FOXC1; ABL1; NFKB1; KAT6A; TFDP2; SMARCD3; CDYL; HBP1; GTF3A; CEBPA; FOXJ1; PBXIP1; ZNF44; ZFHX4; HOXB7; OSR2; RFX5; BCL6; MLXIP; PAWR; ELF5; SOX13; SIAH2; TCF4; TCF7L1; CHD1; IKBKAP; RBPMS; BAZ2B; ZSCAN16; APEX1; CRYM; FLNA; PHF20; HDAC3; SIX1; KLF6; ZFHX3; RBM14; ARID4B; IKZF1; CTBP2; SALL1; ERBB2; BCL3; PAXBP1; ZNF107; TBL1XR1; FOSL2; TCFL5; ZNF217; YAP1; AR; HNRNPD; DBP; BIRC2; ZNF160; TRIM22; CBX7; REPIN1; BRD8; TOB1; STAT5B; ZNF443; KAT6B; NR2F1; HMGB3; CREB1; HIPK1; TAF1D; PNRC1; ZNF331; CBX6; ZNF586; GATA3; TXNIP; SMAD3; IRF4; KLF4; ZBTB18; TBX3