Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75983	Veliparib	GSE92742	MCF10A	Human	24h	0.08uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	302	PPARD; MXD1; NFKBIB; SOHLH2; ETV1; NR1D2; ADRB2; RXRA; E2F2; DLX4; MEOX2; CREB5; KDM5D; FOXC1; NEUROG3; SMAD2; TSC22D4; DYRK1B; POU2F2; BARX2; HDAC11; TFEB; SKI; EHMT1; HABP4; GTF2I; IRF9; IRF5; TRIM25; ZNF506; TFDP2; ING1; MXD4; KLF9; PRDM1; ONECUT2; HNF1B; ID2; CREB3L2; ID4; SHOX; ZNF253; TAF6L; ZNF692; PBX2; FOXE1; YEATS4; ZNF124; MNDA; ETV5; TBX1; RNF141; ZBTB25; ARL2BP; RARG; KDM5A; CERS4; STAT2; SP140; ZNF219; CXXC1; PIAS2; MAP3K10; NFAT5; OVOL1; MBD1; FEV; ZNF623; LZTR1; ZBTB38; ASXL1; PML; HIC1; VGLL1; EBF2; NCOA2; MBD3; PITX3; SOX21; HMBOX1; TBX2; KLF3; PRDM12; ZNF117; E2F8; MEN1; CREM; TEAD1; MYCN; ZNF276; THRAP3; ZNF576; ZNF14; ZNF443; ELF4; HOXA10; BAZ2A; SMARCC2; PRRX2; ZFP36L2; LZTS1; EVX1; ATOH1; RBBP5; HHEX; RXRB; PKNOX2; ZBTB20; ZIC1; NR2F1; MAFK; ZBTB7B; MAML1; ZNF768; ZNF557; ERBB4; RERE; ZNF93; CSDE1; ZNF358; KDM5C; MXD3; GATA6; PCGF3; HDAC4; NR5A1; CDX1; ZBTB43; TBL1X; PBXIP1; ZKSCAN3; HMG20A; LHX3; TLE2; TBX3; ZNF79; NR0B1; ZIM2; FOSL2; MDM4; TAF12; ZNF536; MED12; GATA2; HAND1; ZEB2; MSC; EHMT2; HES1; SPIB; THRB; CSDC2; NKRF; SOX9; NKX2-1; SMAD6; TXNIP; ZNF510; ERBB2; HMGN3; HMGA2; RFX2; HMGXB4; IFNB1; PDLIM1; TAF1C; YBX2; SOX5; ZNF180; ZNF430; PSIP1; NR2F6; PPARGC1A; MNT; POU2F1; BTG1; CBX6; BHLHE41; IL16; SSX1; CHD1; TEAD3; CBX4; GCFC2; PLAGL1; TBL1XR1; ZNF74; NCOA1; MTA1; HMGB1; SATB2; BHLHE40; NFKB2; SIN3B; ZKSCAN5; SMARCD3; TRIM22; EP300; ZNF24; CAMTA1; MAFB; ZBTB32; SMAD7; SP110; MDM2; HOXD3; MYBL1; BRCA1; ZFHX4; TCF4; PRMT2; ZNF75D; PROX1; STAT1; HOXD1; MED13; LYL1; ZBED1; NPAS2; BBX; ZSCAN32; ZNF165; ZNF131; RING1; ING3; ARID3A; ZNF423; CNOT2; XBP1; FOXJ3; SNAI2; HTATIP2; ZFPM2; CCNT1; ZBTB1; ZNF573; SALL1; CERS6; INSR; BATF; CITED1; ZNF432; ZNF267; WIZ; BPTF; NONO; HIC2; RBFOX2; ARID1A; PEG3; UBTF; VPS72; SMAD3; ZNF107; BCL6; RBL2; TAF9B; OSR2; EYA2; NR3C2; ETS1; WWP1; FOXF2; MTF2; E2F3; CARM1; SIX1; NFE2L3; ECD; TSC22D2; ABL1; FOS; JUNB; DBP; ZBED2; MEOX1; PAX5; NFATC3; MYCL; PMF1; PHF20; KLF10; CREB1; CUX1; DAXX; TCFL5; SFPQ; ZNF512B; TGIF1; TWIST1; KAT6B; TLE4; PAX8; KLF13; PFDN5; AHR; WT1; PRRX1; PIR; TOX3; IKBKAP; ZNF91
Down-regulation	324	MYC; HDAC2; SP3; SSRP1; TCEA2; RELA; ZNF32; YBX3; ILF2; HOXB2; SMARCD2; ZNF611; ZNF12; THAP4; ATF2; RAN; BAZ1A; SIRT7; RHOA; CCDC59; ZFP36L1; TTF1; CREB3; TCF25; ZNF263; ING4; EZH2; MAFF; NCOR1; MTDH; INSM1; AIP; ZNF274; USP22; COPS2; CCNC; PGR; FOXM1; CENPF; LOXL2; ZNF226; BRD4; UBE3A; CD3D; ZNF665; ZNF544; MAZ; VEZF1; ZNF83; NFYB; ZNF654; ZMYND11; ZBED4; TAL1; KAT6A; TBPL1; GLI3; HSF2; SETD3; RREB1; RNF2; CBX3; PAXBP1; NKX3-1; RYBP; EED; HMX1; SMARCC1; ENO1; XRCC6; HIVEP2; ZNF160; RFC1; RLF; PEX2; MED24; SF1; KDM5B; FOXA1; ANKRD1; SIAH2; ELK4; ATF6; ZNF646; ZNF84; YBX1; EDF1; ARID5A; SUMO1; ZNF410; ELK1; SCAND1; SMARCE1; SP140L; GTF2A1; NELFB; DRAP1; CDC5L; DR1; TSHZ2; NFKB1; CTCF; CREG1; PSPC1; BCLAF1; DEK; LEF1; RFXAP; NR4A1; ZNF324; MLX; CBFB; HOXA4; SAP30; SIX6; HCFC1; KLF1; IRF1; ESR1; CITED2; TRIM28; ATF5; ZNF146; RB1; CCNA2; ZNF22; TEAD4; ZNF688; ATF4; ITGB3BP; HOXA7; NFKBIA; HIVEP3; PAX6; ZNF551; SNW1; AATF; TCF7; ADNP2; RNF6; HDAC5; ZNF667; RUVBL2; ZNF721; CRYM; NR1H4; THAP1; ARID5B; ZNF23; PSMC3; URI1; ZMIZ1; HMGB2; REXO4; USP16; NFE2L1; HEY1; ZBTB24; YWHAB; HMGA1; TCERG1; CNOT6; SPEN; PITX1; CEBPZ; ERCC3; TAF9; AEBP1; TFCP2L1; SRF; BCL3; DACH1; TAF4; FOSL1; NFATC1; ZNF468; VGLL4; RUNX1; NR1H2; HIPK1; SCMH1; TBP; SUZ12; NHLH2; ST18; FOXO3; IRF2; PCGF2; HSBP1; MED27; HDGF; C1QBP; ID3; ZNF232; AR; BRD2; JUP; PIAS4; HBP1; EN1; SIX2; WWC1; RCOR3; THRA; ZMYM2; THAP11; HMGB3; REST; PTRF; TRIP6; FOXK2; SMAD1; SUPT4H1; MED21; ZNF528; SP100; LHX6; BIRC2; SSBP3; MED1; ELF2; MITF; CEBPG; KAT2B; CBFA2T3; HSF1; CCNE1; ZNF239; ESRRA; ZNF302; NR4A3; ZNF606; BANP; MGA; ZBTB11; HDAC9; SREBF1; SAP18; SMARCA2; BRF2; DLX2; E2F5; REPIN1; SETD2; BRD7; CREB3L1; BACH2; CHD4; ZNF331; RBBP7; CEBPD; EHF; MEF2D; CRK; NR2F2; CALR; TOX; SUB1; ZNF574; PSMD9; STAT3; ZBTB14; ZNF140; ZNF134; ZFX; NCOR2; HDAC3; TGFB1; KLF11; KMT2A; PPRC1; NUP62; HOXC10; GTF2IRD1; ZNF33B; MED6; BRD8; ZNF415; ELF1; KLF2; NEDD8; TOB1; ZNF587; POU2AF1; TAF5; DMTF1; TCF12; SATB1; PAWR; SLC2A4RG; ZNF586; POU4F1; CHD7; BTAF1; PRKDC; STAT6; AGO2; HDAC1; TCEB2; TSC22D1; ZNF281; ASH2L; BCOR; RFXANK; MYB; FLNA; UBE2I; RUNX3; RBM39; FOXO1; SHOX2; IRF7; EMX2; EGR3; CEBPB; BASP1; NRIP1; TRIM29; RFX5; GATA3; ARID4B; TLE1; PBX1; HOXB6