Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75971	Torin-2	GSE92742	MCF10A	Human	6h	0.08uM	EID0436

Response Information :

Types	Number	Response transcription factors
Up-regulation	92	TSC22D3; SMAD3; FOXO4; MNT; RELB; ENO1; KLF6; CRK; BRD8; ZMYND8; HMGN3; MYBL2; TGIF1; HOXA1; NFATC1; BATF; SND1; PURA; CNOT1; FOXD1; ASH2L; KDM2A; HBP1; RBPMS; FOXJ1; FOXC1; STAT6; KLF2; IL16; TCF7L1; BASP1; HTATIP2; STAT5A; NR1H3; PBXIP1; ERG; ELF1; RBL2; KLF7; UBE2B; LHX6; ARNTL; KDM4A; SIM2; ELF3; JARID2; TOB1; NCOR2; KDM5B; RNF141; ARID3B; TSC22D4; CXXC1; FLNA; NCOA6; NR4A2; AIP; EYA2; SMARCC1; HDAC1; MXD4; HMBOX1; PDLIM1; TP53; ELF5; FOSB; DNMT3B; RUNX3; STAT3; DACH1; TSG101; NFIB; KLF9; ATF3; MAFF; NR4A1; YWHAB; HOXC6; ELK3; KLF5; TFCP2L1; PHF20; TBPL1; HOXB7; RUNX1; SMAD2; TWIST1; HMGA2; ID1; CREB3L1; PSMD9; FHL2
Down-regulation	123	HDAC2; USP22; IKBKAP; TRIB3; ZNF248; GMNN; CDK2; SUZ12; DNMT1; ZNF586; ACTL6A; MEIS2; CUX2; ZNF557; SOX11; TAF11; ZNF770; SCAI; SHOX2; POLR3F; ARID5B; SNAI2; TCEA2; SUPT7L; ILF2; ZNF551; ZBTB6; CNOT3; ZNF12; ZNF473; ZNF124; TEAD4; LEF1; ZNF512B; ZNF135; HSF2; PSIP1; PHF2; RRN3; ARNT2; HDAC4; MNDA; TAF5; INSM1; PKNOX2; ZNF623; ZNF304; CERS6; ZNF263; ZNF268; TAF1A; ZNF136; ZNF692; ELK4; RAD21; BACH1; ZNF180; IFI16; ZNF43; ZNF274; RYBP; MGA; HHEX; MED17; SP140L; ZNF544; ZFP36L2; SSX1; ZSCAN9; TAL1; POU4F1; TCF21; UBP1; LHX2; UBE3A; E2F8; TFEC; IRF9; AR; TOPORS; REPIN1; FOXF2; PAXBP1; FOXA1; KAT2B; ZNF22; SMAD6; ZNF350; RNF138; TDP2; PPRC1; ZNF529; HIRA; ZNF329; CTBP1; ZNF232; C1QBP; NKX3-1; SMARCD3; SP3; BBX; ZEB1; HOXB13; HLF; SATB2; IRF8; BNC2; SUB1; SMAD4; NR1H2; MYBL1; PEG3; FOXF1; SOX17; MYRF; TLE4; THAP7; ISL1; TBL1XR1; ZNF652; ZBTB18; TFAP2C; WT1