Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75944	Alvocidib	GSE92742	MCF10A	Human	6h	10uM	EID0436

Response Information :

Types	Number	Response transcription factors
Up-regulation	80	PAX8; ZNF423; HSBP1; TCFL5; SNAI1; FOXO4; SND1; NFIX; PPARD; TCF7; MYCBP; HDAC1; MXD4; MECOM; YBX1; HMGN3; NANOG; NFATC4; HDAC9; FOXJ1; KDM5C; KMT2D; HDAC3; HOXD3; POU5F1B; EZH1; MMS19; TFDP2; ENO1; GTF3A; NFKBIB; CIITA; LHX6; CSDE1; FLNA; YAP1; DNAJC1; PFDN5; STAT5A; EDF1; ZMIZ2; ZNF226; TAF9B; SMAD6; SUPT4H1; WDR77; PDLIM1; LOXL2; MAF; TAF10; LMCD1; NR2F1; TGFB1; CALR; DACH1; TCEB2; ST18; SPDEF; CREB3L1; HLTF; WWTR1; MEIS1; URI1; CTBP2; ZBED2; ID3; HMGA1; FOXF1; RUNX1; JUP; EGR1; TOX; CTNNB1; ID4; AEBP1; RHOA; PSMD9; WT1; EMX2; FOSB
Down-regulation	304	MYC; CCNA2; ADRB2; SUV39H1; FOSL1; TBP; FOXO3; FOS; ARID4B; CEBPZ; THAP11; ZBTB11; HOXA5; TCEA2; CRK; HES1; TLE1; IRF2; CEBPB; BAZ1B; CTCF; ADNP; CENPF; ZFP36L2; RBM14; ABL1; ZNF574; TAF4; NCOA2; BAZ1A; NFYB; ZNF12; ZNF473; ZBTB24; ZNF146; KAT6A; ZBTB1; TAF5; ZNF764; ASXL1; ZBED4; CEBPG; CEBPD; USP22; NRF1; SFPQ; TGS1; PLAGL2; MED17; RLF; TRIB3; ABT1; BACH1; ZNF263; PIAS4; NCOA4; FOXK2; JUND; TTF1; AGO2; SF1; BCOR; TRAF6; NFYA; ZZZ3; E2F6; IKBKAP; NFKBIA; SERTAD2; RUNX3; CCDC59; CRY1; TAF1A; GMNN; TGIF1; DNAJC2; HMGXB4; PHF2; HSF2; XBP1; SAP30; ZNF394; CHD8; SOX11; HDAC4; RRN3; ARID1A; SAFB2; TOPORS; BCL6; NFIL3; POLR3F; SAFB; ZNF7; MYBL1; HOXA10; ZBTB6; KLF10; ZNF227; SNIP1; ZNF443; DNMT1; ELF2; SIX2; MEN1; SIN3B; USP21; THAP4; RNF138; POU2AF1; ERF; ZNF593; TRIM32; SETDB1; BRPF1; SETD2; EED; ZEB1; MGA; ETS2; ZNF180; ZNF195; REL; ZNF202; TAF5L; CHD7; ZNF134; RXRA; FOXM1; CTR9; CAMTA1; ZNF512B; ZNF14; TRRAP; NCOA1; NFE2L2; ZNF236; DDIT3; TRIM27; HOXA1; BLM; ZNF770; RYBP; SP3; RSF1; JUN; ELF1; TMF1; ZNF232; HMGB2; EN1; ADNP2; PPRC1; CHD1; ZNF623; TFAM; ANKRD1; IFI16; ZBTB7A; DDX17; RORA; ZNF184; FOXC1; CDC5L; ZNF84; VEZF1; HOXA7; JUNB; SPEN; RNF111; RAD21; FOXA1; BCL3; KAT8; SUV39H2; MSC; FOXF2; ZNF292; SMAD3; RNF4; CREBZF; ZNF281; SNAI2; ZFP37; PCGF1; ZNF304; ING2; DPF2; MED21; PITX1; LHX2; ZNF45; ZFP36L1; BPTF; TAF9; RNF6; TP63; ELK4; NCOA6; PATZ1; RBM39; ZNF107; HDGF; IRX4; ZNF189; NKX2-2; TSC22D2; ZNF22; ZNF282; MTF2; ILF2; SMAD4; ZNF629; MAFF; REPIN1; AHR; CHD9; PAXBP1; CDK8; CBFB; TCF7L2; ZNF329; ZKSCAN5; GATAD2A; SIRT7; UBE3A; HOXB2; NR3C2; IRF1; SIX1; ZNF675; E2F8; BACH2; WWP1; SOX4; ZFP69B; SUB1; BCLAF1; ZNF267; ZNF551; NRIP1; ZKSCAN1; NPAT; NUP62; KDM5B; OSR2; MAFG; SALL1; MAFB; POU2F1; BCL10; RREB1; BRD4; ELK3; FOXO1; KAT7; KLF11; RCOR1; VPS72; STAT6; TFAP2C; IRF4; BRD3; KLF6; DEAF1; ISL1; PAX5; HIC2; TCF7L1; NKX3-1; GABPB1; AFF1; HLF; CUX2; BMI1; PHF20; SOX13; TRIP6; ZBTB16; ZBTB38; RARA; ZMIZ1; CTBP1; APEX1; THAP10; TLE2; FOSL2; SIAH2; KLF4; MED1; CITED2; TFEC; TBX3; TBL1XR1; SMAD7; ASCL1; OLIG2; MYB; TBL1X; MNDA; FHL2; CDK7; ZIC1; GATA2