Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75793	Saracatinib	GSE92742	MCF10A	Human	6h	10uM	EID0436

Response Information :

Types	Number	Response transcription factors
Up-regulation	68	GATA3; TSC22D3; FOXO4; BRD8; HMGN3; SSBP2; CEBPD; CEBPA; EZH1; NFE2L1; ENO1; BASP1; HDAC5; HOXA5; ESR1; PFDN5; EYA2; STAT5A; RERE; DACH1; HLTF; MECOM; KDM4A; RBBP7; E2F8; RXRA; KAT7; ITGB3BP; PPARGC1A; TP53; TWIST1; BRF2; MEIS1; NR1H3; BTG1; DNMT3B; POLR2A; ZBTB20; PHOX2B; HTATIP2; BRCA1; ZMYND8; MXI1; NFIL3; RUNX3; TOB1; RBBP8; PHOX2A; PIR; SMAD6; ERBB4; SAP18; ZFHX4; PLAGL1; HDAC1; PATZ1; SMARCA2; HMGB2; EMX2; ZBTB16; ZNF302; ELF5; PURA; MYCN; AFF1; HOXB7; ATF3; PSMD9
Down-regulation	80	FOSL1; TRIB3; FOS; ADRB2; HES1; EN1; SNAI2; NFYA; SOX11; HHEX; TGFB1I1; FOXF2; ANKRD1; FLNA; NKX3-1; CAPN15; LEF1; CDK9; ETS1; MTDH; NR2F1; ETV4; BACH1; MAFF; ETS2; POU4F1; HIPK3; AES; EZH2; TGIF1; C1QBP; MYBL1; EGR1; HOXB13; HMGA2; ELK4; SP140L; CBFB; FOXE1; DLX2; TCF21; JUN; MLXIP; ZEB1; NRIP1; SOX9; NR1H2; SATB2; LITAF; LOXL2; CUX1; TBX3; WWTR1; NPAS2; CREB3L2; POU2AF1; ZFP36L1; SMAD4; TSC22D2; SALL1; IFI16; PTRF; ZFP36L2; IRF8; ELK3; RNF138; TGFB1; HIRA; PAX6; TCEA2; ZHX2; FOXF1; CUX2; FOXG1; ASCL1; PEG3; CTNNB1; TFAP2C; FHL2; ID1