Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75753	Torin-2	GSE92742	MCF10A	Human	6h	10uM	EID0435

Response Information :

Types	Number	Response transcription factors
Up-regulation	105	TSC22D3; DDIT3; PNRC1; BCOR; DLX2; TXNIP; RELB; RLF; ING3; ATF4; BTG1; NFKB2; ELF1; EZH1; KLF5; ZNF266; ASXL1; CALCOCO1; ZBTB20; KLF6; HIVEP2; ZNF688; NR1D2; BRD8; FOXO4; NR3C1; FLNA; TOB1; ZNF335; ZNF160; DMTF1; RXRB; RB1; NCOA2; NFIL3; KDM5A; BAZ2A; FOXD1; IRF5; NFE2L1; YBX1; TGFB1; TRIP4; MAZ; PPARGC1A; HOXC4; HMG20B; UBE2B; FOXO3; STAT6; KDM5D; ZNF721; ZNF611; SOX4; SP110; KAT7; ZNF217; SP2; ZFP36L2; HBP1; HDAC1; HOXB7; ZMIZ2; BLZF1; HDAC9; SMAD4; PSPC1; PAX6; TRIM29; DLX5; ZBTB38; IRF7; PBX3; CITED2; ARNTL; PLAG1; PHF20; SCAND1; HOXC6; RAD21; YBX3; SMAD6; ARID4B; STAT5A; PBX1; SIM2; MED1; PTRF; ID1; KLF9; BRD2; PTTG1; MSX1; BHLHE41; ERBB2; BASP1; DACH1; ID4; TOX3; PRKDC; HOXC10; ID3; AEBP1; MAFB; TBX3
Down-regulation	83	FOSL1; WWC1; PPRC1; MYC; CCNE1; ZFP36L1; SUB1; ZBTB18; ZNF146; ZNF281; ELK3; HIPK2; HMGA2; ZNF557; IL16; CBFB; RNF138; GTF2A2; SMARCA5; TAF9; IKBKAP; ZNF516; ZNF586; EGR2; SP3; MED21; E2F6; ADRB2; RBPJ; NFE2L3; ZNF529; BRD7; CREB5; AGO2; TEAD4; ZNF195; SIX2; HLX; TRIM32; NFIC; POU2AF1; CEBPG; EYA1; ANKRD1; CEBPZ; FOS; ZNF107; ZNF22; PITX1; ATN1; HOXA10; HSBP1; SMAD1; VDR; CHD7; SETD3; CERS6; ESR1; UBP1; ETV5; RREB1; IRF2; ETS1; IRF6; CBX6; SOX11; HLF; MAX; E2F3; HIC2; LEF1; ZNF467; MYBL1; MECOM; IFI16; HES1; MEIS2; ZNF239; HOXD1; VGLL4; HHEX; DAXX; TFAP2C