Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75731	Alvocidib	GSE92742	MCF10A	Human	6h	2uM	EID0435

Response Information :

Types	Number	Response transcription factors
Up-regulation	140	DLX2; ZNF331; ZNF667; LHX3; MXD1; ST18; ZNF43; ATOH1; HIPK2; SOX17; PRDM14; PNRC1; PROP1; NFATC4; HOXB1; HOXA6; KMT2D; HOXA3; PRDM12; CDX1; SOX3; ZNF423; CIITA; SPI1; ARNT2; NR5A2; POU2F2; SUMO1; ZNF665; INSM1; TBX1; NR4A1; ACTL6B; ZNF358; AEBP1; HOXD3; SPDEF; RB1; POU3F2; E2F4; HOXD1; TTF2; NR1H2; DDIT3; ARID5B; FOXG1; SOX5; ZNF573; MED14; ZBTB20; NFIX; DLX5; TCEB2; HLX; DACH1; PAX6; CDIP1; TFAP2A; EHMT1; CREBL2; FLI1; BACH2; ZNF83; CHD4; GTF2I; ZBED2; ID3; ZNF141; WDR77; NOC2L; HOXB5; KLF7; ZNF91; ID4; KDM5C; RBL2; MECOM; SOHLH2; HIPK3; GLI2; SOX2; PAWR; ZIC3; MED12; PBX3; CEBPE; NR0B2; ZNF117; TAF9B; HIF1A; TAL1; TWIST1; BCL11A; E2F2; NFE2L2; ZNF711; ZNF562; NR1I2; JUP; NR4A2; EPAS1; MYT1L; LIN28A; ZNF415; ARL2BP; ERBB4; WT1; KLF5; ZNF93; ZNF611; TGFB1; SHOX2; TOX; FOXO4; NFE2; VPS72; ZNF165; ZSCAN18; ETS1; MAF; ZMYND8; HDAC9; MYCN; ID1; MXD4; VDR; FOXF2; HBP1; ZNF160; CREB1; TXNIP; KLF9; CCNH; ZIC1; BHLHE41; MEIS1; KLF11; NFATC3; PEG3; MEIS2
Down-regulation	328	MYC; CRK; MYCBP; NFKBIA; FOSL1; FHL2; CDK7; CEBPB; MED6; ELK3; ADNP; TRIM16; SUB1; XBP1; ZBTB24; SNIP1; PHF2; SNW1; RLF; SETD2; ELF1; PATZ1; POLR3F; RBM14; HOXA11; DPF2; CCNA2; REST; DNAJC2; RNF111; BRPF1; EZH2; TCF12; DDX54; SIRT7; CHD1; NR3C1; FOXO3; HCFC2; ZNF212; PUF60; TRIM32; SIX2; ABL1; UBP1; ARID4B; SP3; TBL1XR1; HOXA10; RBBP5; EED; ZNF394; NRIP1; BCL3; CCDC59; SFMBT1; KLF2; ZBTB11; SFPQ; MLX; NRBF2; ITGB3BP; RNF4; SAFB2; MGA; BAZ1A; TAF4; NCOA4; TAF5; NUP62; YAF2; LIMD1; MED23; ATF1; PIAS1; BAZ1B; RUNX3; KAT7; VEZF1; MYNN; HMG20A; HSF2; ZNF263; RREB1; PSPC1; SOX4; ADRB2; ZNF574; PIAS3; MAFG; ADNP2; CEBPA; THAP1; PCGF2; NFYC; DR1; IKZF5; ZNF473; ZNF45; SIN3B; ZNF14; DDX5; NR2C1; CBFB; ZBTB14; NR2F2; ZNF629; NKX3-1; MTF2; AFF1; DNAJC1; TRIP4; TRIP6; AGO2; VGLL4; SERTAD2; CENPB; SP100; ORC2; MAML1; NCOA6; NRF1; BLM; BCL10; ZNF443; KDM2A; TERF2; PPRC1; ZNF324; NPAS2; CREBZF; TGS1; FOXM1; ZNF282; NFYA; SETDB1; HMGXB4; NELFB; CTR9; MED17; ZKSCAN1; FOXA1; ATF7IP; TTF1; ZNF410; ZNF764; ZZZ3; TCERG1; IRX4; UIMC1; ZNF7; POU2AF1; ZFP36L2; KDM5A; RELA; ECD; ZBTB1; BRD3; TRAF6; GMNN; CTCF; BCLAF1; ETS2; ZFP64; ZNF281; EYA2; ERF; ZNF146; TFAM; ERCC3; ETV4; MEF2A; SMARCC1; ZBTB40; SF1; CRY1; IRX5; SMARCD1; HMGA2; NFIL3; ZNF267; COPS2; POLR2A; ZNF107; CHD9; GABPB1; ZNF430; TGFB1I1; WWTR1; SMAD3; TRIM27; ZNF16; BMI1; ZSCAN32; ELF2; NKRF; PITX1; ZMYND11; CENPF; E2F6; ESR1; SP140L; RNF138; IKBKAP; ZNF12; TAF1D; CHD3; RORA; ZBTB18; MED24; CLOCK; TRIP11; PIAS2; CITED1; TSC22D2; ZBTB38; POU2F1; NPAT; ZNF337; TGIF1; PAXBP1; DNMT3B; HES1; BTAF1; MDFI; STAT6; SMAD2; BRD8; TFAP2C; ZMYM2; ZNF227; JARID2; RCOR1; ZNF516; ZNF24; SP140; NAB1; BIRC2; SMAD7; MTDH; NFIC; BHLHE40; KLF10; CEBPZ; HLF; SIAH2; STAT1; ATF4; MED4; TRIM22; ZNF512B; HOXC6; ING1; BAZ2B; ZNF292; ETV5; AATF; IRF2; HOXA5; FOXC1; DEAF1; OSR2; SIM2; SOX9; GATAD2A; BRCA1; ELF3; ZNF148; FOXJ3; ZEB1; PHF8; KMT2A; JUND; PCGF1; SMARCA2; TAF11; KDM5B; RBM39; ARNTL2; NFKB1; IRF1; HLTF; ZNF652; TFCP2; TRIM28; ZNF552; SIX1; RBBP4; TULP4; HMGB2; JUN; REPIN1; MED1; MED21; IFI16; TBP; PIR; RFX5; STAT4; E2F3; DAXX; TBX3; PHF20; TFCP2L1; PURA; REL; IRF7; SUV39H1; ZNF432; MYRF; NPM1; NFIB; TP53; JUNB; HOXC10; ELF5; CREB3L2; ERBB2; NCOR2; USP22; SAP30; TBL1X; TCF7; LITAF; TLE1; FOS; RBPMS; MAFB