Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75730	Alvocidib	GSE92742	MCF10A	Human	6h	10uM	EID0435

Response Information :

Types	Number	Response transcription factors
Up-regulation	64	EGR1; NR5A2; HAND1; DRAP1; RNF141; ZNF226; MXD1; PHOX2B; STAT2; NR1H2; HDAC1; HSBP1; FOXJ1; NFATC4; ZNF532; STAT3; AEBP1; KDM5C; SUMO1; RARG; HTATIP2; FOXO4; MSX1; ZSCAN18; DLX5; ID3; ARNTL2; TSG101; MYCN; CBX6; JUP; ASCL1; RHOA; TGIF2; TAF10; IRF4; HDAC9; LMCD1; MTA1; PAWR; VPS72; PLAGL1; CARHSP1; ZNF423; HMBOX1; SMARCB1; HLTF; STAT6; LEF1; CTNNB1; MXD4; CREB3L1; KDM5D; TWIST1; HOXC10; CALR; FOXF1; TCF4; LITAF; PEG3; HEY1; MYRF; PDLIM1; PBX1
Down-regulation	283	MYC; FOSL1; CDK7; FHL2; ZNF12; ADNP; CEBPB; ZBTB24; ADNP2; KAT6A; XBP1; TAF4; ZNF574; TRIM32; RRN3; RNF111; NRBF2; FOXO3; CTCF; RLF; ZNF263; ZNF443; MED17; POLR3F; SNIP1; BAZ1B; NFKBIA; ADRB2; ABL1; ZNF200; ZNF473; FOXM1; CCNA2; ZFP36L1; ZNF394; CDC5L; ZNF7; TGIF1; HOXA10; REST; MAML1; ZNF16; PPRC1; BRPF1; ESR1; PATZ1; ARID4B; KAT7; TRIM27; ZBTB1; ZFP36L2; ZNF629; RNF138; SIRT7; EYA2; MED6; SIN3B; ZNF180; NPAT; ZBTB11; ZNF212; TAF5; BHLHE40; CHD7; TGS1; ZNF430; IRF2; ZBTB18; ZNF202; NFIL3; ZKSCAN5; NRF1; ZNF227; NFYA; GMNN; PHF2; SMAD7; CRK; HSF2; NKRF; ZBTB7A; CCNE1; ZNF551; NR3C1; KLF2; GATA3; DPF2; ZNF134; ZBTB14; ABT1; AHR; JUN; SALL1; RREB1; CTBP2; TRAF6; TAF5L; TAF7; ZNF324; BCL10; ZBTB43; NR2C1; CAPN15; ZNF696; SERTAD2; ZMYND11; BCOR; ZNF512B; MED21; GMEB2; ZNF292; SETD2; CHD1; MAFB; ZNF45; ZZZ3; ARID1A; PHIP; ZBED4; ZSCAN32; CRY1; TSC22D2; CHD9; CHD8; DEAF1; HOXA7; ZNF136; HMGXB4; ING1; RBM14; NRIP1; ZNF14; ZNF557; TFAP2C; MTF2; ARID4A; NR4A2; ZNF3; ZNF107; MYBL1; BAZ2B; TAF9; MAX; CRYM; AFF1; NR3C2; SF1; KLF10; UBE2I; FOXA1; SMAD4; AGO2; TERF2; SAFB2; HLF; TP63; ZNF184; POU2AF1; ING2; BAZ1A; RCOR1; SMARCC2; MGA; ETS2; BACH1; MED1; ATF7IP; IFI16; ZSCAN9; TTF1; FOXG1; DNAJC2; EGR2; BCLAF1; TOPORS; UBP1; ZNF273; POU4F1; SIAH2; TRIB3; RELA; ZNF146; NFIC; ZFP64; CBX7; ERCC3; ZNF195; ZNF22; KMT2A; NKX3-1; ZNF267; NPAS2; HMGA2; ZBTB16; OLIG2; DNMT3B; CCDC59; ZNF248; TRIM16; TRPS1; CBX4; ELK3; ELF5; PKNOX1; RERE; SOX4; ZHX2; PSPC1; ETV5; PLAGL2; ELF3; SNAI2; CEBPZ; NUP62; CNOT6; MED13; SP3; CITED2; PNRC1; E2F6; CEBPD; IRF1; KDM5B; MAFF; ZEB1; CAMTA1; FOXD1; CITED1; RORA; POLR2A; THAP10; HOXA5; BRD2; HIVEP1; TBL1XR1; TFCP2; ZMIZ1; ING3; BRD4; REPIN1; JUND; NCOA4; EHF; ATF3; ZNF148; TLE2; HES1; SATB2; ZNF468; ZNF217; DAXX; BTG1; ZEB2; AES; MEN1; E2F3; SMARCA2; JARID2; RYBP; PQBP1; RNF6; TRIM29; HIC2; NPM1; TRIP6; SUV39H1; KLF4; ZNF232; TBX3; REL; ZFPM2; SOX11; ZNF91; PCGF2; KLF11; TOB1; OSR2; TBP; ZIC1; RFX5; NFIB; HOXB2; BASP1