Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID75725	Roscovitine	GSE92742	MCF10A	Human	6h	0.08uM	EID0435

Response Information :

Types	Number	Response transcription factors
Up-regulation	68	BCL11B; TCF15; EGR3; TSC22D1; DPF2; POU2F2; DDIT3; PA2G4; HTATIP2; EGR4; DLX2; PIAS2; SMARCE1; HDAC1; DNAJC1; NFKBIB; ELF1; TSC22D4; NCOA6; PAX5; KDM2A; FOSL1; CHD4; NR4A1; E2F2; FOXD1; TCEB2; FLNA; POU2AF1; TOB1; KAT5; ESR1; NR1H2; ZNF165; TWIST1; HOXB7; MTF2; BAZ1A; KLF5; AATF; POLR2A; MYT1L; PAWR; LEF1; PURA; ID1; SPEN; PHF20; NKX2-2; SOX17; E2F3; MXD4; MECOM; ERG; MAFB; TCF4; FOSB; PDLIM1; HMGA1; SCAND1; ID3; ZNF423; SOX9; BASP1; HHEX; TLE1; ERBB2; HOXC6
Down-regulation	115	THAP11; TCEA2; GMNN; ZNF274; ZNF586; IRF9; NCOA2; HLF; TAF7; FOXN3; ZNF264; ZNF12; ZNF304; ZNF180; ZNF536; SP100; PKNOX2; DNMT1; ZNF136; BPTF; ZBTB44; CREBL2; TRAK1; ZHX2; SIX2; PRMT2; NR1D2; ZNF551; AHR; SMARCA1; BCL11A; SSBP2; HDAC5; ATF1; ZNF175; SUPT7L; MED13; BRIP1; ZNF33B; ZNF117; THAP10; CNOT6; CERS6; SMAD4; WWP1; HMGA2; BNC2; ARID1A; PRRX1; PLAGL1; CD3D; ZNF195; ZNF91; MYBL1; TRIM24; RYBP; GATA6; ZMYND11; KAT2B; MYCL; ZNF652; CHD9; PBX3; TLE2; IFI16; RAD21; ZNF512B; SMAD6; WWTR1; TFEC; PAXBP1; MEIS2; ZNF32; TBX3; HIVEP1; PPP1R13L; TERF1; INSR; ZIC1; SOX13; NR2F1; ZNF124; ZNF148; ZNF22; SMAD7; ZSCAN18; ZBTB18; ETV5; TCF21; HOXD1; NCOA4; ZEB1; HIC2; PLAG1; ZBTB38; SALL2; CREB1; WT1; NPM1; PEG3; NRIP1; JUND; TRPS1; ZFPM2; BTG1; MXI1; SNAI2; HEY1; MYRF; KDM5D; PCGF2; HDAC6; TOX3; CITED2; ID4